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MSC Promotes the Secretion of Exosomal lncRNA KLF3-AS1 to Regulate Sphk1 Through YY1-Musashi-1 Axis and Improve Cerebral Ischemia-Reperfusion Injury.
Cao Y, Wang D, Zhou D. Cao Y, et al. Among authors: zhou d. Mol Neurobiol. 2024 May 13. doi: 10.1007/s12035-024-04150-3. Online ahead of print. Mol Neurobiol. 2024. PMID: 38735900
Stroke remains the 3rd leading cause of long-term disability globally. Over the past decade, mesenchymal stem cell (MSC) transplantation has been proven as an effective therapy for ischemic stroke. ...
Stroke remains the 3rd leading cause of long-term disability globally. Over the past decade, mesenchymal stem cell (MSC) transplantat …
Ultrasmall Fe3O4 nanoparticles self-assembly induced dual-mode T1/T2-weighted magnetic resonance imaging and enhanced tumor synergetic theranostics.
Xie Q, Wang X, Zhang G, Zhou D, Zhao Y, Liu H, Duan J, Yu D, Sang Y. Xie Q, et al. Among authors: zhou d. Sci Rep. 2024 May 9;14(1):10646. doi: 10.1038/s41598-024-59525-2. Sci Rep. 2024. PMID: 38724530 Free PMC article.
The self-assembled ultrasmall Fe(3)O(4) nanoclusters synthesized by facilely modifying ultrasmall Fe(3)O(4) nanoparticles with 2,3-dimercaptosuccinic acid (DMSA) molecule possess long-term stability and mass production ability. The proposed ultrasmall Fe(3)O(4) nanocluster …
The self-assembled ultrasmall Fe(3)O(4) nanoclusters synthesized by facilely modifying ultrasmall Fe(3)O(4) nanoparticles with 2,3-dimercapt …
Improving crop health by synthetic microbial communities: Progress and prospects.
Weng LY, Luan DD, Zhou DP, Guo QG, Wang GZ, Zhang JL. Weng LY, et al. Among authors: zhou dp. Ying Yong Sheng Tai Xue Bao. 2024 Mar 18;35(3):847-857. doi: 10.13287/j.1001-9332.202403.028. Ying Yong Sheng Tai Xue Bao. 2024. PMID: 38646773 Review. English.
At present, agrochemicals such as fertilizers and pesticides are mainly used in agricultural production to promote crop health. However, long-term excessive utilization of agrochemicals will damage the ecological environment of farmlands and increase the safety risk of agr …
At present, agrochemicals such as fertilizers and pesticides are mainly used in agricultural production to promote crop health. However, lon …
Short-term efficacy and safety of neoadjuvant pyrotinib plus taxanes for early HER2-positive breast cancer: a single-arm exploratory phase II trial.
Ye G, Chen P, Liu X, He T, Pivot X, Pan R, Zhou D, Zhu L, Zhang K, Li W, Yang S, Lin J, Cai G, Huang H. Ye G, et al. Among authors: zhou d. Gland Surg. 2024 Mar 27;13(3):374-382. doi: 10.21037/gs-24-38. Epub 2024 Mar 22. Gland Surg. 2024. PMID: 38601287 Free PMC article.
CONCLUSIONS: In female patients with HER2-positive non-metastatic BC, neoadjuvant pyrotinib monotherapy plus taxanes appears to show promising clinical benefit and controllable AEs [Chinese Clinical Trial Registry (ChiCTR2100050870)]. The long-term efficacy and safety of t …
CONCLUSIONS: In female patients with HER2-positive non-metastatic BC, neoadjuvant pyrotinib monotherapy plus taxanes appears to show promisi …
An ultra-small organic dye nanocluster for enhancing NIR-II imaging-guided surgery outcomes.
Wang Y, Zhou D, Ma H, Liu D, Liang Y, Zhu S. Wang Y, et al. Among authors: zhou d. Eur J Nucl Med Mol Imaging. 2024 Apr 6. doi: 10.1007/s00259-024-06702-0. Online ahead of print. Eur J Nucl Med Mol Imaging. 2024. PMID: 38581443
However, the inherent self-assembly of organic dyes has led to high accumulation in main organs, resulting in significant background signals and potential long-term toxicity. METHODS: We rationalize the donor structure of donor-acceptor-donor-based dyes to control the self …
However, the inherent self-assembly of organic dyes has led to high accumulation in main organs, resulting in significant background signals …
Bimetallic nanoparticles as cascade sensitizing amplifiers for low-dose and robust cancer radio-immunotherapy.
Wang Y, Wang L, Li T, Ouyang M, Xiong H, Zhou D. Wang Y, et al. Among authors: zhou d. Acta Pharm Sin B. 2024 Apr;14(4):1787-1800. doi: 10.1016/j.apsb.2023.11.028. Epub 2023 Nov 30. Acta Pharm Sin B. 2024. PMID: 38572091 Free PMC article.
As a result, OXA/Fe NPs-based low-dose RT triggered a robust immune response and inhibited the distant and metastatic tumors effectively by a strong abscopal effect. Moreover, a long-term immunological memory effect to protect mice from tumor rechallenging is observed. ...
As a result, OXA/Fe NPs-based low-dose RT triggered a robust immune response and inhibited the distant and metastatic tumors effectively by …
Efficacy and Safety of Long-Term Dual Antiplatelet Therapy: A Systematic Review and Meta-Analysis.
Zhang X, Zhou D, Song S, Huang X, Ding Y, Meng R. Zhang X, et al. Among authors: zhou d. Clin Appl Thromb Hemost. 2024 Jan-Dec;30:10760296241244772. doi: 10.1177/10760296241244772. Clin Appl Thromb Hemost. 2024. PMID: 38571479 Free PMC article.
Previous meta-analyses reported conflicting results about the effects of long-term and short-term as well as non-DAPT use in various clinical settings. ...RESULTS: A total of 34 randomized studies involving 141 455 patients were finally included. In comparison with …
Previous meta-analyses reported conflicting results about the effects of long-term and short-term as well as non-DAPT use in v …
Nanoparticle targeting of neutrophil glycolysis prevents lung ischemia-reperfusion injury.
Liao F, Scozzi D, Zhou D, Maksimos M, Diedrich C, Cano M, Tague LK, Liu Z, Haspel JA, Leonard JM, Li W, Krupnick AS, Wong BW, Kreisel D, Azab AK, Gelman AE. Liao F, et al. Among authors: zhou d. Am J Transplant. 2024 Mar 24:S1600-6135(24)00238-7. doi: 10.1016/j.ajt.2024.03.028. Online ahead of print. Am J Transplant. 2024. PMID: 38522826
Neutrophils exacerbate pulmonary ischemia-reperfusion injury (IRI) resulting in poor short and long-term outcomes for lung transplant recipients. Glycolysis powers neutrophil activation, but it remains unclear if neutrophil-specific targeting of this pathway will inhibit I …
Neutrophils exacerbate pulmonary ischemia-reperfusion injury (IRI) resulting in poor short and long-term outcomes for lung transplant …
Current clinical findings of acute neurological syndromes after SARS-CoV-2 infection.
Wang M, Wang J, Ren Y, Lu L, Xiong W, Li L, Xu S, Tang M, Yuan Y, Xie Y, Li W, Chen L, Zhou D, Ying B, Li J. Wang M, et al. Among authors: zhou d. MedComm (2020). 2024 Mar 9;5(3):e508. doi: 10.1002/mco2.508. eCollection 2024 Mar. MedComm (2020). 2024. PMID: 38463395 Free PMC article.
The findings underscore the urgency of continuous investigation Neuro-COVID to unravel the complexities of this relationship, and pivotal in addressing the long-term consequences of COVID-19 on neurological health....
The findings underscore the urgency of continuous investigation Neuro-COVID to unravel the complexities of this relationship, and pivotal in …
Neuroinflammatory response on a newly combinatorial cell-cell interaction chip.
Zhao Y, Lv X, Chen Y, Zhang C, Zhou D, Deng Y. Zhao Y, et al. Among authors: zhou d. Biomater Sci. 2024 Apr 16;12(8):2096-2107. doi: 10.1039/d4bm00125g. Biomater Sci. 2024. PMID: 38441146
Moreover, an innovative hydrophilic treatment process on the glass surface facilitated long-term co-culture of cells. The developed neuroinflammation model on the chip revealed that SH-SY5Y cytotoxicity was predominantly influenced by co-cultured THP-1 cells. ...
Moreover, an innovative hydrophilic treatment process on the glass surface facilitated long-term co-culture of cells. The developed n …
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