Nanoparticle targeting of neutrophil glycolysis prevents lung ischemia-reperfusion injury.
Liao F, Scozzi D, Zhou D, Maksimos M, Diedrich C, Cano M, Tague LK, Liu Z, Haspel JA, Leonard JM, Li W, Krupnick AS, Wong BW, Kreisel D, Azab AK, Gelman AE.
Liao F, et al. Among authors: zhou d.
Am J Transplant. 2024 Mar 24:S1600-6135(24)00238-7. doi: 10.1016/j.ajt.2024.03.028. Online ahead of print.
Am J Transplant. 2024.
PMID: 38522826
Neutrophils exacerbate pulmonary ischemia-reperfusion injury (IRI) resulting in poor short and long-term outcomes for lung transplant recipients. Glycolysis powers neutrophil activation, but it remains unclear if neutrophil-specific targeting of this pathway will inhibit I …
Neutrophils exacerbate pulmonary ischemia-reperfusion injury (IRI) resulting in poor short and long-term outcomes for lung transplant …