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Page 1
Long-Term Outcome of Severe Metabolic Acidemia in ICU Patients, a BICAR-ICU Trial Post Hoc Analysis.
Bendiab E, Garnier F, Soler M, Fosset M, Jaber S, Molinari N, Jung B; BICAR-ICU Investigators. Bendiab E, et al. Crit Care Med. 2023 Jan 1;51(1):e1-e12. doi: 10.1097/CCM.0000000000005706. Epub 2022 Nov 8. Crit Care Med. 2023. PMID: 36351174 Clinical Trial.
OBJECTIVES: Long-term prognosis of ICU survivors is a major issue. Severe acidemia upon ICU admission is associated with very high short-term mortality. Since the long-term prognosis of these patients is unknown, we aimed to determine the long-term hea …
OBJECTIVES: Long-term prognosis of ICU survivors is a major issue. Severe acidemia upon ICU admission is associated with very high sh …
The Critically Ill Kidney Transplant Recipient: A Narrative Review.
Canet E, Zafrani L, Azoulay É. Canet E, et al. Among authors: zafrani l. Chest. 2016 Jun;149(6):1546-55. doi: 10.1016/j.chest.2016.01.002. Epub 2016 Jan 18. Chest. 2016. PMID: 26836919 Review.
Hospital mortality can reach 30% and correlates with acute illness severity and reason for ICU admission. Transplant characteristics are not predictors of short-term survival. Graft survival depends on pre-ICU graft function, disease severity, and renal toxicity of ICU inv …
Hospital mortality can reach 30% and correlates with acute illness severity and reason for ICU admission. Transplant characteristics are not …
How Protective are Antibodies to SARS-CoV-2, the Main Weapon of the B-Cell Response?
Pons S, Uhel F, Frapy E, Sérémé Y, Zafrani L, Aschard H, Skurnik D. Pons S, et al. Among authors: zafrani l. Stem Cell Rev Rep. 2023 Apr;19(3):585-600. doi: 10.1007/s12015-022-10477-y. Epub 2022 Nov 24. Stem Cell Rev Rep. 2023. PMID: 36422774 Free PMC article. Review.
Given the persistence of SARS-CoV-2 and its ability to develop new variants, the implementation of an effective and long-term herd immunity appears to be crucial to overcome the pandemic. ...
Given the persistence of SARS-CoV-2 and its ability to develop new variants, the implementation of an effective and long-term herd im …
Gastrointestinal bleeding in critically ill immunocompromised patients.
Catano J, Sacleux SC, Gornet JM, Camus M, Bigé N, Saliba F, Azoulay E, Dumas G, Zafrani L. Catano J, et al. Among authors: zafrani l. Ann Intensive Care. 2021 Aug 21;11(1):130. doi: 10.1186/s13613-021-00913-6. Ann Intensive Care. 2021. PMID: 34420114 Free PMC article.
By multivariate analysis, mortality was associated with hemorrhagic shock (OR 2.91, IC95% 1.33-6.38, p = 0 .01), upper GIB (OR 4.33, CI95% 1.50-12.47, p = 0.01), and long-term corticosteroid therapy before admission (OR 2.98, CI95% 1.32-6.71, p = 0.01). ...CONCLUSION: Mort …
By multivariate analysis, mortality was associated with hemorrhagic shock (OR 2.91, IC95% 1.33-6.38, p = 0 .01), upper GIB (OR 4.33, CI95% 1 …
Strongyloides stercoralis hyperinfection syndrome: a case series and a review of the literature.
Geri G, Rabbat A, Mayaux J, Zafrani L, Chalumeau-Lemoine L, Guidet B, Azoulay E, Pène F. Geri G, et al. Among authors: zafrani l. Infection. 2015 Dec;43(6):691-8. doi: 10.1007/s15010-015-0799-1. Epub 2015 May 26. Infection. 2015. PMID: 26008854 Review.
Underlying immunosuppression was present in 127 patients, mostly long-term corticosteroid treatment in 111 (83.5 %) patients. Fever (80.8 %), respiratory (88.6 %), and gastrointestinal (71.2 %) symptoms were common clinical manifestations. ...
Underlying immunosuppression was present in 127 patients, mostly long-term corticosteroid treatment in 111 (83.5 %) patients. Fever ( …
Post-traumatic stress disorder and quality of life alterations in survivors of immune-mediated thrombotic thrombocytopenic purpura and atypical hemolytic and uremic syndrome.
Azoulay E, Souppart V, Kentish-Barnes N, Benhamou Y, Joly BS, Zafrani L, Joseph A, Canet E, Presne C, Grall M, Zerbib Y, Provot F, Fadlallah J, Mariotte E, Urbina T, Veyradier A, Coppo P. Azoulay E, et al. Among authors: zafrani l. J Crit Care. 2023 Aug;76:154283. doi: 10.1016/j.jcrc.2023.154283. Epub 2023 Mar 15. J Crit Care. 2023. PMID: 36931181
Thrombotic thrombocytopenic purpura (iTTP) and atypical hemolytic-uremic syndrome (aHUS), once in remission, may cause long-term symptoms, among which mental-health impairments may be difficult to detect. ...
Thrombotic thrombocytopenic purpura (iTTP) and atypical hemolytic-uremic syndrome (aHUS), once in remission, may cause long-term symp …
Post-remission outcomes in AML patients with high hyperleukocytosis and inaugural life-threatening complications.
Fodil S, Chevret S, Rouzaud C, Valade S, Rabian F, Mariotte E, Raffoux E, Itzykson R, Boissel N, Sébert M, Adès L, Zafrani L, Azoulay E, Lengliné E. Fodil S, et al. Among authors: zafrani l. PLoS One. 2022 Jul 7;17(7):e0270744. doi: 10.1371/journal.pone.0270744. eCollection 2022. PLoS One. 2022. PMID: 35797337 Free PMC article.
Retrospective studies showed that several symptomatic measures might decrease early death rate but long-term data are scarce. We aimed to analyze whether the therapeutic measures carried out urgently at diagnosis may influence the outcome among HL AML patients having achie …
Retrospective studies showed that several symptomatic measures might decrease early death rate but long-term data are scarce. We aime …
Pattern of Brain Injury in Patients With Thrombotic Thrombocytopenic Purpura in the Precaplacizumab Era.
Mirouse A, Legriel S, Dumas G, Labro G, Veyradier A, Zafrani L, Valade S, Hourmant Y, Boutboul D, Darmon M, Coppo P, Mariotte E, Azoulay E. Mirouse A, et al. Among authors: zafrani l. Crit Care Med. 2021 Oct 1;49(10):e931-e940. doi: 10.1097/CCM.0000000000005164. Crit Care Med. 2021. PMID: 34166282
OBJECTIVES: To describe short- and long-term neurologic prognosis of patients with thrombotic thrombocytopenic purpura and to identify clusters associated with evolution. ...
OBJECTIVES: To describe short- and long-term neurologic prognosis of patients with thrombotic thrombocytopenic purpura and to identif …
Clinical Warburg effect in lymphoma patients admitted to intensive care unit.
Chaba A, Fodil S, Lemiale V, Mariotte E, Valade S, Azoulay E, Zafrani L. Chaba A, et al. Among authors: zafrani l. Ann Intensive Care. 2023 Oct 5;13(1):97. doi: 10.1186/s13613-023-01192-z. Ann Intensive Care. 2023. PMID: 37796407 Free PMC article.
BACKGROUND: The Warburg effect, characterized by elevated lactate levels without tissue hypoxia or shock, has been described in patients with aggressive lymphoproliferative malignancies. However, the clinical characteristics and long-term outcomes in this population remain …
BACKGROUND: The Warburg effect, characterized by elevated lactate levels without tissue hypoxia or shock, has been described in patients wit …
Long-term Quality of Life in Adult Patients Surviving Purpura Fulminans: An Exposed-Unexposed Multicenter Cohort Study.
Contou D, Canoui-Poitrine F, Coudroy R, Préau S, Cour M, Barbier F, Terzi N, Schnell G, Galbois A, Zafrani L, Zuber B, Ehrmann S, Gelisse E, Colling D, Schmidt M, Jaber S, Conia A, Sonneville R, Colin G, Guérin L, Roux D, Jochmans S, Kentish-Barnes N, Audureau E, Layese R, Alves A, Ouedraogo R, Brun-Buisson C, Mekontso Dessap A, de Prost N; Hopeful Study Group. Contou D, et al. Among authors: zafrani l. Clin Infect Dis. 2019 Jul 2;69(2):332-340. doi: 10.1093/cid/ciy901. Clin Infect Dis. 2019. PMID: 30335142 Free article.
BACKGROUND: Long-term health-related quality of life (HR-QOL) of patients surviving the acute phase of purpura fulminans (PF) has not been evaluated. ...Among the 37 exposed patients, those who required limb amputation (n = 12/37 [32%]) exhibited lower PCS (34 [IQR, 24-38] …
BACKGROUND: Long-term health-related quality of life (HR-QOL) of patients surviving the acute phase of purpura fulminans (PF) has not …
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