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ACOX1 deficiency-induced lipid metabolic disorder facilitates chronic interstitial fibrosis development in renal allografts.
Zhang YH, Bin Liu, Meng Q, Zhang D, Yang H, Li G, Wang Y, Liu M, Liu N, Yu J, Liu S, Zhou H, Xu ZX, Wang Y. Zhang YH, et al. Among authors: xu zx. Pharmacol Res. 2024 Mar;201:107105. doi: 10.1016/j.phrs.2024.107105. Epub 2024 Feb 16. Pharmacol Res. 2024. PMID: 38367917 Free article.
Chronic interstitial fibrosis presents a significant challenge to the long-term survival of transplanted kidneys. Our research has shown that reduced expression of acyl-coenzyme A oxidase 1 (ACOX1), which is the rate-limiting enzyme in the peroxisomal fatty acid beta-oxida …
Chronic interstitial fibrosis presents a significant challenge to the long-term survival of transplanted kidneys. Our research has sh …
A real-world disproportionality analysis of mesalazine data mining of the public version of FDA adverse event reporting system.
Liu M, Gu L, Zhang Y, Zhou H, Wang Y, Xu ZX. Liu M, et al. Among authors: xu zx. Front Pharmacol. 2024 Jan 31;15:1290975. doi: 10.3389/fphar.2024.1290975. eCollection 2024. Front Pharmacol. 2024. PMID: 38357304 Free PMC article.
Background: Mesalazine, a preparation of 5-aminosalicylic acid, is a medication widely used in clinical practice as a first-line therapy in the treatment of mild and moderate inflammatory bowel disease. However, the long-term safety of mesalazine in large sample population …
Background: Mesalazine, a preparation of 5-aminosalicylic acid, is a medication widely used in clinical practice as a first-line therapy in …
Development and management of gastrointestinal symptoms in long-term COVID-19.
He KY, Lei XY, Zhang L, Wu DH, Li JQ, Lu LY, Laila UE, Cui CY, Xu ZX, Jian YP. He KY, et al. Among authors: xu zx. Front Microbiol. 2023 Dec 14;14:1278479. doi: 10.3389/fmicb.2023.1278479. eCollection 2023. Front Microbiol. 2023. PMID: 38156008 Free PMC article. Review.
In the current review, we summarized recent reports regarding the long-term effects of COVID-19 (long COVID) on the gastrointestine. OBJECTIVE: To provide a narrative review of abundant clinical evidence regarding the development and management of long-term GI sympt …
In the current review, we summarized recent reports regarding the long-term effects of COVID-19 (long COVID) on the gastrointestine. …
Targeted changes in blood lipids improves fibrosis in renal allografts.
Zhang YH, Liu B, Meng Q, Zhang D, Yang H, Li G, Wang Y, Zhou H, Xu ZX, Wang Y. Zhang YH, et al. Among authors: xu zx. Lipids Health Dis. 2023 Dec 4;22(1):215. doi: 10.1186/s12944-023-01978-x. Lipids Health Dis. 2023. PMID: 38049842 Free PMC article.
BACKGROUND: Chronic interstitial fibrosis is the primary barrier against the long-term survival of transplanted kidneys. Extending the lifespan of allografts is vital for ensuring the long-term health of patients undergoing kidney transplants. ...
BACKGROUND: Chronic interstitial fibrosis is the primary barrier against the long-term survival of transplanted kidneys. Extending th …
HSPB2 facilitates neural regeneration through autophagy for sensorimotor recovery after traumatic brain injury.
Huang Y, Meng S, Wu B, Shi H, Wang Y, Xiang J, Li J, Shi Z, Wu G, Lyu Y, Jia X, Hu J, Xu ZX, Gao Y. Huang Y, et al. Among authors: xu zx. JCI Insight. 2023 Aug 22;8(16):e168919. doi: 10.1172/jci.insight.168919. JCI Insight. 2023. PMID: 37606039 Free PMC article.
Upon creating a tamoxifen-induced neuron-specific HSPB2 overexpression transgenic mouse model, we found that elevated HSPB2 levels promoted long-term sensorimotor recovery and alleviated tissue loss after TBI. ...Treatment with the autophagy inhibitor chloroquine during th …
Upon creating a tamoxifen-induced neuron-specific HSPB2 overexpression transgenic mouse model, we found that elevated HSPB2 levels promoted …
[Determination of seven paraben preservatives in aquatic seasoning using solid-phase extraction coupled with high performance liquid chromatography].
Ning XP, Yao Q, Xu ZX, Yin Y, Liu H, Zhang XY, Ding T, Zhang Y, Hou Y, Wang MR, Wu LN, Tang QT. Ning XP, et al. Among authors: xu zx. Se Pu. 2023 Jun 8;41(6):513-519. doi: 10.3724/SP.J.1123.2022.10004. Se Pu. 2023. PMID: 37259876 Free PMC article. Chinese.
Seven parabens are widely used in soy sauce, vinegar, jam, oyster sauce, stuffing, and other foods. The long-term intake of large amounts of parabens and similar substances may be harmful to the human body. ...
Seven parabens are widely used in soy sauce, vinegar, jam, oyster sauce, stuffing, and other foods. The long-term intake of large amo …
Nexuses Between the Chemical Design and Performance of Small Molecule Dopant-Free Hole Transporting Materials in Perovskite Solar Cells.
Khan D, Liu X, Qu G, Nath AR, Xie P, Xu ZX. Khan D, et al. Among authors: xu zx. Small. 2023 Mar;19(11):e2205926. doi: 10.1002/smll.202205926. Epub 2022 Dec 5. Small. 2023. PMID: 36470653 Review.
Perovskite solar cells (PSCs) have grabbed much attention of researchers owing to their quick rise in power conversion efficiency (PCE). However, long-term stability remains a hurdle in commercialization, partly due to the inclusion of necessary hygroscopic dopants in hole …
Perovskite solar cells (PSCs) have grabbed much attention of researchers owing to their quick rise in power conversion efficiency (PCE). How …
Synergy Effect of a π-Conjugated Ionic Compound: Dual Interfacial Energy Level Regulation and Passivation to Promote Voc and Stability of Planar Perovskite Solar Cells.
Liu X, Min J, Chen Q, Liu T, Qu G, Xie P, Xiao H, Liou JJ, Park T, Xu ZX. Liu X, et al. Among authors: xu zx. Angew Chem Int Ed Engl. 2022 Mar 7;61(11):e202117303. doi: 10.1002/anie.202117303. Epub 2022 Jan 31. Angew Chem Int Ed Engl. 2022. PMID: 35060264
Notably, the synergy effect elevated the intrinsic endothermic decomposition temperature of the perovskite. The modified devices showed excellent long-term thermal (85 C) and operational stability at the maximum power point for 1000 h at 45 C under continuous one-sun illum …
Notably, the synergy effect elevated the intrinsic endothermic decomposition temperature of the perovskite. The modified devices showed exce …
Molecular Design Strategy in Developing Titanyl Phthalocyanines as Dopant-Free Hole-Transporting Materials for Perovskite Solar Cells: Peripheral or Nonperipheral Substituents?
Hu Q, Rezaee E, Li M, Chen Q, Cao Y, Mayukh M, McGrath DV, Xu ZX. Hu Q, et al. Among authors: xu zx. ACS Appl Mater Interfaces. 2019 Oct 9;11(40):36535-36543. doi: 10.1021/acsami.9b09490. Epub 2019 Sep 25. ACS Appl Mater Interfaces. 2019. PMID: 31536319
Experimental and computational analysis suggests more compact molecular packing for NP-SC(6)-TiOPc than P-SC(6)-TiOPc in the solid state due to stronger pi-pi interactions, leading to thin films with better quality and higher performance in hole extraction and transportation. PSC …
Experimental and computational analysis suggests more compact molecular packing for NP-SC(6)-TiOPc than P-SC(6)-TiOPc in the solid state due …
Caspase-2 promotes AMPA receptor internalization and cognitive flexibility via mTORC2-AKT-GSK3β signaling.
Xu ZX, Tan JW, Xu H, Hill CJ, Ostrovskaya O, Martemyanov KA, Xu B. Xu ZX, et al. Nat Commun. 2019 Aug 9;10(1):3622. doi: 10.1038/s41467-019-11575-1. Nat Commun. 2019. PMID: 31399584 Free PMC article.
We found that caspase-2 deficiency led to deficits in dendritic spine pruning, internalization of AMPA receptors and long-term depression. Our results indicate that caspase-2 degrades Rictor, a key mTOR complex 2 (mTORC2) component, to inhibit Akt activation, which leads t …
We found that caspase-2 deficiency led to deficits in dendritic spine pruning, internalization of AMPA receptors and long-term depres …
15 results