HSPB2 facilitates neural regeneration through autophagy for sensorimotor recovery after traumatic brain injury.
Huang Y, Meng S, Wu B, Shi H, Wang Y, Xiang J, Li J, Shi Z, Wu G, Lyu Y, Jia X, Hu J, Xu ZX, Gao Y.
Huang Y, et al. Among authors: xu zx.
JCI Insight. 2023 Aug 22;8(16):e168919. doi: 10.1172/jci.insight.168919.
JCI Insight. 2023.
PMID: 37606039
Free PMC article.
Upon creating a tamoxifen-induced neuron-specific HSPB2 overexpression transgenic mouse model, we found that elevated HSPB2 levels promoted long-term sensorimotor recovery and alleviated tissue loss after TBI. ...Treatment with the autophagy inhibitor chloroquine during th …
Upon creating a tamoxifen-induced neuron-specific HSPB2 overexpression transgenic mouse model, we found that elevated HSPB2 levels promoted …