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Early Growth Response Protein 1 Exacerbates Murine Inflammatory Bowel Disease by Transcriptional Activation of Matrix Metalloproteinase 12.
Chen SY, Fang CY, Su BH, Chen HM, Huang SC, Wu PT, Shiau AL, Wu CL. Chen SY, et al. Among authors: wu cl. Biomedicines. 2024 Apr 2;12(4):780. doi: 10.3390/biomedicines12040780. Biomedicines. 2024. PMID: 38672136 Free PMC article.
Inflammatory bowel disease (IBD) is an inflammatory condition affecting the colon and small intestine, with Crohn's disease and ulcerative colitis being the major types. Individuals with long-term IBD are at an increased risk of developing colorectal cancer. ...
Inflammatory bowel disease (IBD) is an inflammatory condition affecting the colon and small intestine, with Crohn's disease and ulcerative c …
HPN328, a Trispecific T Cell-activating Protein Construct Targeting DLL3-Expressing Solid Tumors.
Molloy ME, Aaron WH, Barath M, Bush MC, Callihan EC, Carlin K, Cremin M, Evans T, Gamez Guerrero M, Hemmati G, Hundal AS, Lao L, Laurie P, Lemon BD, Lin SJ, O'Rear J, Patnaik P, Sotelo Rocha S, Santiago L, Strobel KL, Valenzuela LB, Wu CH, Yu S, Yu TZ, Anand BS, Law CL, Sun LL, Wesche H, Austin RJ. Molloy ME, et al. Among authors: wu ch. Mol Cancer Ther. 2024 Apr 27. doi: 10.1158/1535-7163.MCT-23-0524. Online ahead of print. Mol Cancer Ther. 2024. PMID: 38670552
In an immunocompetent mouse model expressing a human CD3epsilon epitope, mice previously treated with HPN328 withstood tumor rechallenge, demonstrating long-term anti-tumor immunity. When repeat doses were administered to cynomolgus monkeys, HPN328 was well tolerated up to …
In an immunocompetent mouse model expressing a human CD3epsilon epitope, mice previously treated with HPN328 withstood tumor rechallenge, de …
Assessing the impacts of crop production on climate change: An in-depth analysis of long-term determinants and policy implications.
Osei-Kusi F, Wu CS, Akiti SO. Osei-Kusi F, et al. Among authors: wu cs. Environ Monit Assess. 2024 Apr 26;196(5):479. doi: 10.1007/s10661-024-12609-y. Environ Monit Assess. 2024. PMID: 38664253
This research investigates the long-term determinants of carbon emissions in three diverse regions-Europe and Central Asia (ECA), Sub-Saharan Africa (SSA), and the Middle East and North Africa (MENA)-spanning 1990 to 2020. ...
This research investigates the long-term determinants of carbon emissions in three diverse regions-Europe and Central Asia (ECA), Sub …
Long-term bladder outcomes using a prescriber pattern scoring system for posterior urethral valves.
Haney NM, Sholklapper T, Crigger C, Griggs-Demmin A, Mudalegundi S, DiCarlo HN, Gearhart JP, Smith EA, Wu CQ. Haney NM, et al. Among authors: wu cq. J Pediatr Urol. 2024 Apr 4:S1477-5131(24)00180-3. doi: 10.1016/j.jpurol.2024.03.026. Online ahead of print. J Pediatr Urol. 2024. PMID: 38653666
BACKGROUND: Urinary drainage for posterior urethral valves can be achieved with valve ablation (VA) or diversion by vesicostomy (VES) or cutaneous ureterostomy (CU). The effect of these interventions on long-term bladder function remains debated, and voiding symptomatology …
BACKGROUND: Urinary drainage for posterior urethral valves can be achieved with valve ablation (VA) or diversion by vesicostomy (VES) or cut …
Metagenome-assembled genomes from enrichment cultures grown on xenobiotic solvents.
Jia C, Wu C, Li Y, Wang S, Liu J, Liu J, Su H, Tian X, Li J. Jia C, et al. Among authors: wu c. Microbiol Resour Announc. 2024 Apr 23:e0010724. doi: 10.1128/mra.00107-24. Online ahead of print. Microbiol Resour Announc. 2024. PMID: 38651915
Microbes play a significant role in the cleanup of xenobiotic contaminants. Based on metagenomes derived from long-term enrichment cultures grown on xenobiotic solvents, we report 166 metagenome-assembled genomes, of which 137 are predicted to be more than 90% complete. .. …
Microbes play a significant role in the cleanup of xenobiotic contaminants. Based on metagenomes derived from long-term enrichment cu …
Nitrogen fertilization modulates rice phyllosphere functional genes and pathogens through fungal communities.
Wu WF, Li XY, Chen SC, Jin BJ, Wu CY, Li G, Sun CL, Zhu YG, Lin XY. Wu WF, et al. Among authors: wu cy. Sci Total Environ. 2024 Apr 19;929:172622. doi: 10.1016/j.scitotenv.2024.172622. Online ahead of print. Sci Total Environ. 2024. PMID: 38642761
However, studies regarding how the composition and functions of the phyllosphere microbiome respond to agricultural practices, like nitrogen fertilization, are limited. This study investigated the effects of long-term nitrogen fertilization with different levels (CK, N90, …
However, studies regarding how the composition and functions of the phyllosphere microbiome respond to agricultural practices, like nitrogen …
Global incidence, prevalence, years lived with disability (YLDs), disability-adjusted life-years (DALYs), and healthy life expectancy (HALE) for 371 diseases and injuries in 204 countries and territories and 811 subnational locations, 1990-2021: a systematic analysis for the Global Burden of Disease Study 2021.
GBD 2021 Diseases and Injuries Collaborators. GBD 2021 Diseases and Injuries Collaborators. Lancet. 2024 Apr 15:S0140-6736(24)00757-8. doi: 10.1016/S0140-6736(24)00757-8. Online ahead of print. Lancet. 2024. PMID: 38642570
Age-standardised DALY rates due to injuries decreased globally by 24.0% (20.7-27.2) between 2010 and 2021, although improvements were not uniform across locations, ages, and sexes. Globally, HALE at birth improved slightly, from 61.3 years (58.6-63.6) in 2010 to 62.2 years …
Age-standardised DALY rates due to injuries decreased globally by 24.0% (20.7-27.2) between 2010 and 2021, although improvements were not un …
Exploring the impact of dexmedetomidine on short-term outcomes in critically ill sepsis-associated encephalopathy patients.
Tang J, Zhong ZG, Wu CD. Tang J, et al. Among authors: wu cd. Eur Rev Med Pharmacol Sci. 2024 Apr;28(7):2724-2736. doi: 10.26355/eurrev_202404_35901. Eur Rev Med Pharmacol Sci. 2024. PMID: 38639512
OBJECTIVE: Dexmedetomidine has demonstrated potential in preclinical medical research as a protective agent against inflammatory injuries and a provider of neuroprotective benefits. However, its effect on the short-term prognosis of patients with sepsis-associated encephal …
OBJECTIVE: Dexmedetomidine has demonstrated potential in preclinical medical research as a protective agent against inflammatory injuries an …
Projected Time for the Elimination of Cervical Cancer Under Various Intervention Scenarios: Age-Period-Cohort Macrosimulation Study.
Chen YC, Chen YY, Su SY, Jhuang JR, Chiang CJ, Yang YW, Lin LJ, Wu CC, Lee WC. Chen YC, et al. Among authors: wu cc. JMIR Public Health Surveill. 2024 Apr 18;10:e46360. doi: 10.2196/46360. JMIR Public Health Surveill. 2024. PMID: 38635315 Free article.
BACKGROUND: The World Health Organization aims for the global elimination of cervical cancer, necessitating modeling studies to forecast long-term outcomes. OBJECTIVE: This paper introduces a macrosimulation framework using age-period-cohort modeling and population attribu …
BACKGROUND: The World Health Organization aims for the global elimination of cervical cancer, necessitating modeling studies to forecast lon …
2,252 results