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Metabolic effects of an essential amino acid supplement in adolescents with PCOS and obesity.
Fordham TM, Morelli NS, Garcia-Reyes Y, Ware MA, Rahat H, Sundararajan D, Fuller KNZ, Severn C, Pyle L, Malloy CR, Jin ES, Parks EJ, Wolfe RR, Cree MG. Fordham TM, et al. Among authors: wolfe rr. Obesity (Silver Spring). 2024 Apr;32(4):678-690. doi: 10.1002/oby.23988. Epub 2024 Mar 4. Obesity (Silver Spring). 2024. PMID: 38439205 Clinical Trial.
Surprisingly, during the EAA phase, participants reported consuming fewer carbohydrates (p = 0.038) and total sugars (p = 0.046). CONCLUSIONS: Similar to studies in older adults, short-term EAA supplementation in adolescents resulted in significantly lower liver fat, AST, …
Surprisingly, during the EAA phase, participants reported consuming fewer carbohydrates (p = 0.038) and total sugars (p = 0.046). CONCLUSION …
The anabolic role of the Warburg, Cori-cycle and Crabtree effects in health and disease.
Soeters PB, Shenkin A, Sobotka L, Soeters MR, de Leeuw PW, Wolfe RR. Soeters PB, et al. Among authors: wolfe rr. Clin Nutr. 2021 May;40(5):2988-2998. doi: 10.1016/j.clnu.2021.02.012. Epub 2021 Feb 17. Clin Nutr. 2021. PMID: 33674148 Free article. Review.
In evolution, genes survived that could code for metabolic pathways, promoting long term survival during famines or fasting when suffering from trauma, disease or during physiological growth. ...
In evolution, genes survived that could code for metabolic pathways, promoting long term survival during famines or fasting when suff …
Essential amino acid-enriched whey enhances post-exercise whole-body protein balance during energy deficit more than iso-nitrogenous whey or a mixed-macronutrient meal: a randomized, crossover study.
Gwin JA, Church DD, Hatch-McChesney A, Allen JT, Wilson MA, Varanoske AN, Carrigan CT, Murphy NE, Margolis LM, Carbone JW, Wolfe RR, Ferrando AA, Pasiakos SM. Gwin JA, et al. Among authors: wolfe rr. J Int Soc Sports Nutr. 2021 Jan 7;18(1):4. doi: 10.1186/s12970-020-00401-5. J Int Soc Sports Nutr. 2021. PMID: 33413462 Free PMC article. Clinical Trial.
We measured protein kinetics after consuming iso-nitrogenous amounts of free-form essential amino acid-enriched whey (EAA + W; 34.7 g protein, 24 g EAA sourced from whey and free-form EAA), whey (WHEY; 34.7 g protein, 18.7 g EAA), or a mixed-macronutrient meal (MEAL; 34.7 g prote …
We measured protein kinetics after consuming iso-nitrogenous amounts of free-form essential amino acid-enriched whey (EAA + W; 34.7 g protei …
Serum biomarkers that predict lean mass loss over bed rest in older adults: An exploratory study.
Gawel SH, Davis GJ, Luo M, Deutz NEP, Wolfe RR, Pereira SL. Gawel SH, et al. Among authors: wolfe rr. Clin Chim Acta. 2020 Oct;509:72-78. doi: 10.1016/j.cca.2020.06.003. Epub 2020 Jun 4. Clin Chim Acta. 2020. PMID: 32505773 Free article.
BACKGROUND: Lean mass (LM) loss during extended bed rest contributes to long term functional decline in older adults. Identifying blood biomarkers that predict a hospitalized individual's risk of losing LM could allow for timely intervention. ...
BACKGROUND: Lean mass (LM) loss during extended bed rest contributes to long term functional decline in older adults. Identifying blo …
A randomized study of dietary composition during weight-loss maintenance: Rationale, study design, intervention, and assessment.
Ebbeling CB, Klein GL, Luoto PK, Wong JMW, Bielak L, Eddy RG, Steltz SK, Devlin C, Sandman M, Hron B, Shimy K, Heymsfield SB, Wolfe RR, Wong WW, Feldman HA, Ludwig DS. Ebbeling CB, et al. Among authors: wolfe rr. Contemp Clin Trials. 2018 Feb;65:76-86. doi: 10.1016/j.cct.2017.12.004. Epub 2017 Dec 9. Contemp Clin Trials. 2018. PMID: 29233719 Free PMC article.
BACKGROUND: While many people with overweight or obesity can lose weight temporarily, most have difficulty maintaining weight loss over the long term. Studies of dietary composition typically focus on weight loss, rather than weight-loss maintenance, and rely on nutrition …
BACKGROUND: While many people with overweight or obesity can lose weight temporarily, most have difficulty maintaining weight loss over the …
Short term elevation in dietary protein intake does not worsen insulin resistance or lipids in older adults with metabolic syndrome: a randomized-controlled trial.
Kim IY, Schutzler SE, Azhar G, Wolfe RR, Ferrando AA, Coker RH. Kim IY, et al. Among authors: wolfe rr. BMC Nutr. 2017;3:33. doi: 10.1186/s40795-017-0152-4. Epub 2017 Apr 17. BMC Nutr. 2017. PMID: 28713581 Free PMC article.
The purpose of the study was to determine the influence of a short-term elevation in dietary protein on hepatic and peripheral insulin sensitivity in twelve older subjects (51-70 yrs) with metabolic syndrome. ...Moreover, fasting lipid was not affected by RPI or EPI. CONCL …
The purpose of the study was to determine the influence of a short-term elevation in dietary protein on hepatic and peripheral insuli …
Safety and performance benefits of arginine supplements for military personnel: a systematic review.
Brooks JR, Oketch-Rabah H, Low Dog T, Gorecki DK, Barrett ML, Cantilena L, Chung M, Costello RB, Dwyer J, Hardy ML, Jordan SA, Maughan RJ, Marles RJ, Osterberg RE, Rodda BE, Wolfe RR, Zuniga JM, Valerio LG Jr, Jones D, Deuster P, Giancaspro GI, Sarma ND. Brooks JR, et al. Among authors: wolfe rr. Nutr Rev. 2016 Nov;74(11):708-721. doi: 10.1093/nutrit/nuw040. Nutr Rev. 2016. PMID: 27753625 Review.
RESULTS: Most studies had few participants and suggested risk of bias that could negatively affect the results. l-Arginine supplementation provided little enhancement of athletic performance or improvements in recovery. Short-term supplementation with arginine may result i …
RESULTS: Most studies had few participants and suggested risk of bias that could negatively affect the results. l-Arginine supplementation p …
Postprandial muscle protein synthesis is higher after a high whey protein, leucine-enriched supplement than after a dairy-like product in healthy older people: a randomized controlled trial.
Luiking YC, Deutz NE, Memelink RG, Verlaan S, Wolfe RR. Luiking YC, et al. Among authors: wolfe rr. Nutr J. 2014 Jan 22;13:9. doi: 10.1186/1475-2891-13-9. Nutr J. 2014. PMID: 24450500 Free PMC article. Clinical Trial.
CONCLUSIONS: Ingestion of a high whey protein, leucine-enriched supplement resulted in a larger overall postprandial muscle protein synthesis rate in healthy older subjects compared with a conventional dairy product. This acute effect is promising for long-term effects on …
CONCLUSIONS: Ingestion of a high whey protein, leucine-enriched supplement resulted in a larger overall postprandial muscle protein synthesi …
Long-term oxandrolone treatment increases muscle protein net deposition via improving amino acid utilization in pediatric patients 6 months after burn injury.
Tuvdendorj D, Chinkes DL, Zhang XJ, Suman OE, Aarsland A, Ferrando A, Kulp GA, Jeschke MG, Wolfe RR, Herndon DN. Tuvdendorj D, et al. Among authors: wolfe rr. Surgery. 2011 May;149(5):645-53. doi: 10.1016/j.surg.2010.12.006. Epub 2011 Feb 18. Surgery. 2011. PMID: 21333314 Free PMC article. Clinical Trial.
Protein breakdown at the whole-body level was not different between the groups. CONCLUSION: Long-term oxandrolone treatment increased net deposition of leg muscle protein during AA infusion by attenuating protein breakdown, but did not affect whole-body protein breakdown.. …
Protein breakdown at the whole-body level was not different between the groups. CONCLUSION: Long-term oxandrolone treatment increased …
42 results