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Long-term starvation and ageing induce AGE-1/PI 3-kinase-dependent translocation of DAF-16/FOXO to the cytoplasm.
BMC Biol. 2006 Feb 3;4:1. doi: 10.1186/1741-7007-4-1.
BMC Biol. 2006.
PMID: 16457721
Free PMC article.
RESULTS: We find that in L1s both starvation and daf-16 are necessary to confer resistance to oxidative stress in the form of hydrogen peroxide. Accordingly, DAF-16 is localised to cell nuclei after short-term starvation. However, after long-term starvation, DAF-16 …
RESULTS: We find that in L1s both starvation and daf-16 are necessary to confer resistance to oxidative stress in the form of hydrogen perox …
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