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Long-term (180-Day) Outcomes in Critically Ill Patients With COVID-19 in the REMAP-CAP Randomized Clinical Trial.
Writing Committee for the REMAP-CAP Investigators; Higgins AM, Berry LR, Lorenzi E, Murthy S, McQuilten Z, Mouncey PR, Al-Beidh F, Annane D, Arabi YM, Beane A, van Bentum-Puijk W, Bhimani Z, Bonten MJM, Bradbury CA, Brunkhorst FM, Burrell A, Buzgau A, Buxton M, Charles WN, Cove M, Detry MA, Estcourt LJ, Fagbodun EO, Fitzgerald M, Girard TD, Goligher EC, Goossens H, Haniffa R, Hills T, Horvat CM, Huang DT, Ichihara N, Lamontagne F, Marshall JC, McAuley DF, McGlothlin A, McGuinness SP, McVerry BJ, Neal MD, Nichol AD, Parke RL, Parker JC, Parry-Billings K, Peters SEC, Reyes LF, Rowan KM, Saito H, Santos MS, Saunders CT, Serpa-Neto A, Seymour CW, Shankar-Hari M, Stronach LM, Turgeon AF, Turner AM, van de Veerdonk FL, Zarychanski R, Green C, Lewis RJ, Angus DC, McArthur CJ, Berry S, Derde LPG, Gordon AC, Webb SA, Lawler PR. Writing Committee for the REMAP-CAP Investigators, et al. Among authors: webb sa. JAMA. 2023 Jan 3;329(1):39-51. doi: 10.1001/jama.2022.23257. JAMA. 2023. PMID: 36525245 Free PMC article.
IMPORTANCE: The longer-term effects of therapies for the treatment of critically ill patients with COVID-19 are unknown. OBJECTIVE: To determine the effect of multiple interventions for critically ill adults with COVID-19 on longer-term outcomes. DESIGN, SETTING, AN …
IMPORTANCE: The longer-term effects of therapies for the treatment of critically ill patients with COVID-19 are unknown. OBJECTIVE: T …
Embedding clinical trials within routine health-care delivery: Challenges and opportunities.
Howard-Jones AR, Webb SA. Howard-Jones AR, et al. Among authors: webb sa. J Paediatr Child Health. 2021 Apr;57(4):474-476. doi: 10.1111/jpc.15354. Epub 2021 Mar 3. J Paediatr Child Health. 2021. PMID: 33656215 Free PMC article.
Thoughtful integration of trials into routine bedside care will enable pragmatic research outcomes, tangible returns on financial investments and improved decision-making for patients in the medium- to long-term....
Thoughtful integration of trials into routine bedside care will enable pragmatic research outcomes, tangible returns on financial investment …
Quality of Life and 1-Year Survival in Patients With Early Septic Shock: Long-Term Follow-Up of the Australasian Resuscitation in Sepsis Evaluation Trial.
Higgins AM, Peake SL, Bellomo R, Cooper DJ, Delaney A, Harris AH, Howe BD, Nichol AD, Webb SA, Williams PJ; Australasian Resuscitation in Sepsis Evaluation (ARISE) Investigators and the ANZICS Clinical Trials Group. Higgins AM, et al. Among authors: webb sa. Crit Care Med. 2019 Jun;47(6):765-773. doi: 10.1097/CCM.0000000000003762. Crit Care Med. 2019. PMID: 30985391 Clinical Trial.
OBJECTIVES: To examine long-term survival and quality of life of patients with early septic shock. ...INTERVENTIONS: Early goal-directed therapy versus usual care. MEASUREMENTS AND MAIN RESULTS: Long-term survival was measured up to 12 months postrandomization. Heal …
OBJECTIVES: To examine long-term survival and quality of life of patients with early septic shock. ...INTERVENTIONS: Early goal-direc …
Large expert-curated database for benchmarking document similarity detection in biomedical literature search.
Brown P; RELISH Consortium; Zhou Y. Brown P, et al. Database (Oxford). 2019 Jan 1;2019:baz085. doi: 10.1093/database/baz085. Database (Oxford). 2019. PMID: 33326193 Free PMC article.
We further show that the three representative baseline methods used to generate recommended articles for evaluation (Okapi Best Matching 25, Term Frequency-Inverse Document Frequency and PubMed Related Articles) had similar overall performances. ...
We further show that the three representative baseline methods used to generate recommended articles for evaluation (Okapi Best Matching 25, …
Effect of Early Sustained Prophylactic Hypothermia on Neurologic Outcomes Among Patients With Severe Traumatic Brain Injury: The POLAR Randomized Clinical Trial.
Cooper DJ, Nichol AD, Bailey M, Bernard S, Cameron PA, Pili-Floury S, Forbes A, Gantner D, Higgins AM, Huet O, Kasza J, Murray L, Newby L, Presneill JJ, Rashford S, Rosenfeld JV, Stephenson M, Vallance S, Varma D, Webb SAR, Trapani T, McArthur C; POLAR Trial Investigators and the ANZICS Clinical Trials Group. Cooper DJ, et al. Among authors: webb sar. JAMA. 2018 Dec 4;320(21):2211-2220. doi: 10.1001/jama.2018.17075. JAMA. 2018. PMID: 30357266 Free PMC article. Clinical Trial.
IMPORTANCE: After severe traumatic brain injury, induction of prophylactic hypothermia has been suggested to be neuroprotective and improve long-term neurologic outcomes. OBJECTIVE: To determine the effectiveness of early prophylactic hypothermia compared with normothermic …
IMPORTANCE: After severe traumatic brain injury, induction of prophylactic hypothermia has been suggested to be neuroprotective and improve …
Changes in case-mix and outcomes of critically ill patients in an Australian tertiary intensive care unit.
Williams TA, Ho KM, Dobb GJ, Finn JC, Knuiman MW, Webb SA. Williams TA, et al. Among authors: webb sa. Anaesth Intensive Care. 2010 Jul;38(4):703-9. doi: 10.1177/0310057X1003800414. Anaesth Intensive Care. 2010. PMID: 20715735
This study aimed to assess the changes in characteristics of critically ill patients and their effect on long-term outcome. This cohort study utilised linked data between the intensive care unit database and state-wide morbidity and mortality databases. ...In conclusion, a …
This study aimed to assess the changes in characteristics of critically ill patients and their effect on long-term outcome. This coho …
Effect of length of stay in intensive care unit on hospital and long-term mortality of critically ill adult patients.
Williams TA, Ho KM, Dobb GJ, Finn JC, Knuiman M, Webb SA; Royal Perth Hospital ICU Data Linkage Group. Williams TA, et al. Among authors: webb sa. Br J Anaesth. 2010 Apr;104(4):459-64. doi: 10.1093/bja/aeq025. Epub 2010 Feb 25. Br J Anaesth. 2010. PMID: 20185517 Free article.
Increasing LOS in ICU was not associated with an increased risk of in-hospital mortality after adjusting for other covariates, but was associated with an increased risk of long-term mortality after hospital discharge. The variability on the long-term mortality effec …
Increasing LOS in ICU was not associated with an increased risk of in-hospital mortality after adjusting for other covariates, but was assoc …
Landmark survival as an end-point for trials in critically ill patients--comparison of alternative durations of follow-up: an exploratory analysis.
Taori G, Ho KM, George C, Bellomo R, Webb SA, Hart GK, Bailey MJ. Taori G, et al. Among authors: webb sa. Crit Care. 2009;13(4):R128. doi: 10.1186/cc7988. Epub 2009 Aug 4. Crit Care. 2009. PMID: 19653888 Free PMC article.
A validation cohort involving 4609 patients admitted during same time period with identical diagnoses from 55 ICUs across Australia (CORE cohort) was used to compare the patient characteristics and in-hospital survival to look at the Australia-wide applicability of the long te …
A validation cohort involving 4609 patients admitted during same time period with identical diagnoses from 55 ICUs across Australia (CORE co …
Very old patients admitted to intensive care in Australia and New Zealand: a multi-centre cohort analysis.
Bagshaw SM, Webb SA, Delaney A, George C, Pilcher D, Hart GK, Bellomo R. Bagshaw SM, et al. Among authors: webb sa. Crit Care. 2009;13(2):R45. doi: 10.1186/cc7768. Epub 2009 Apr 1. Crit Care. 2009. PMID: 19335921 Free PMC article.
Those aged >or= 80 years were more likely to be discharged to rehabilitation/long-term care (12.3% vs. 4.9%, OR = 2.7, 95% CI = 2.6 to 2.9). The admission rates of very old patients increased by 5.6% per year. ...
Those aged >or= 80 years were more likely to be discharged to rehabilitation/long-term care (12.3% vs. 4.9%, OR = 2.7, 95% CI = 2. …
Estimating long-term survival of critically ill patients: the PREDICT model.
Ho KM, Knuiman M, Finn J, Webb SA. Ho KM, et al. Among authors: webb sa. PLoS One. 2008 Sep 17;3(9):e3226. doi: 10.1371/journal.pone.0003226. PLoS One. 2008. PMID: 18797505 Free PMC article.
BACKGROUND: Long-term survival outcome of critically ill patients is important in assessing effectiveness of new treatments and making treatment decisions. ...SIGNIFICANCE: Age, gender, co-morbidities, severity of acute illness, and the intensity and duration of intensive …
BACKGROUND: Long-term survival outcome of critically ill patients is important in assessing effectiveness of new treatments and makin …
16 results