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Vicia faba Peptide Network Supplementation Does Not Differ From Milk Protein in Modulating Changes in Muscle Size During Short-Term Immobilization and Subsequent Remobilization, but Increases Muscle Protein Synthesis Rates During Remobilization in Healthy Young Men.
Weijzen MEG, Holwerda AM, Jetten GHJ, Houben LHP, Kerr A, Davis H, Keogh B, Khaldi N, Verdijk LB, van Loon LJC. Weijzen MEG, et al. Among authors: verdijk lb. J Nutr. 2023 Jun;153(6):1718-1729. doi: 10.1016/j.tjnut.2023.01.014. Epub 2023 Jan 11. J Nutr. 2023. PMID: 37277162 Clinical Trial.
CONCLUSION: NPN_1 supplementation does not differ from milk protein in modulating the loss of muscle size during short-term immobilization and the regain during remobilization in young men. ...
CONCLUSION: NPN_1 supplementation does not differ from milk protein in modulating the loss of muscle size during short-term immobiliz …
Nutritional supplementation to enhance the efficacy of exercise training in older adults: what is the evidence from the latest randomized controlled trials?
Verdijk LB. Verdijk LB. Curr Opin Clin Nutr Metab Care. 2021 Nov 1;24(6):504-510. doi: 10.1097/MCO.0000000000000792. Curr Opin Clin Nutr Metab Care. 2021. PMID: 34596062 Review.
PURPOSE OF REVIEW: This review summarizes recent studies that assessed whether nutritional supplementation enhances the efficacy of exercise training in older adults, focusing on the benefits for physical/functional performance of protein, vitamin D, or multi-ingredient supplemen …
PURPOSE OF REVIEW: This review summarizes recent studies that assessed whether nutritional supplementation enhances the efficacy of exercise …
A Nitrate-Rich Vegetable Intervention Elevates Plasma Nitrate and Nitrite Concentrations and Reduces Blood Pressure in Healthy Young Adults.
van der Avoort CMT, Jonvik KL, Nyakayiru J, van Loon LJC, Hopman MTE, Verdijk LB. van der Avoort CMT, et al. Among authors: verdijk lb. J Acad Nutr Diet. 2020 Aug;120(8):1305-1317. doi: 10.1016/j.jand.2020.02.014. Epub 2020 May 5. J Acad Nutr Diet. 2020. PMID: 32386891 Clinical Trial.
Fasting mean systolic and diastolic blood pressure did not change, but mean systolic and diastolic blood pressure assessed 2.5 hours after lunch were significantly reduced throughout both intervention periods (P<0.05), with no differences between beetroot juice and nitrate-ric …
Fasting mean systolic and diastolic blood pressure did not change, but mean systolic and diastolic blood pressure assessed 2.5 hours after l …
Postexercise cooling impairs muscle protein synthesis rates in recreational athletes.
Fuchs CJ, Kouw IWK, Churchward-Venne TA, Smeets JSJ, Senden JM, Lichtenbelt WDVM, Verdijk LB, van Loon LJC. Fuchs CJ, et al. Among authors: verdijk lb. J Physiol. 2020 Feb;598(4):755-772. doi: 10.1113/JP278996. Epub 2019 Dec 29. J Physiol. 2020. PMID: 31788800 Free PMC article.
In addition, deuterated water ((2) H(2) O) was applied with the collection of saliva, blood and muscle biopsies over 2 weeks to assess the effects of postexercise cooling with protein intake on myofibrillar protein synthesis rates during more prolonged resistance-type exercise tr …
In addition, deuterated water ((2) H(2) O) was applied with the collection of saliva, blood and muscle biopsies over 2 weeks to assess the e …
Skeletal muscle unloading results in increased mitophagy and decreased mitochondrial biogenesis regulation.
Leermakers PA, Kneppers AEM, Schols AMWJ, Kelders MCJM, de Theije CC, Verdijk LB, van Loon LJC, Langen RCJ, Gosker HR. Leermakers PA, et al. Among authors: verdijk lb. Muscle Nerve. 2019 Dec;60(6):769-778. doi: 10.1002/mus.26702. Epub 2019 Oct 23. Muscle Nerve. 2019. PMID: 31495926 Free PMC article.
METHODS: We analyzed a comprehensive set of molecular markers involved in mitochondrial-autophagy, -biogenesis, -dynamics, and -content, in the gastrocnemius muscle of C57BL/6J mice subjected to 0- and 3-days hind limb suspension, and in biopsies from human vastus lateralis muscl …
METHODS: We analyzed a comprehensive set of molecular markers involved in mitochondrial-autophagy, -biogenesis, -dynamics, and -content, in …
Protein Intake Falls below 0.6 g•kg-1•d-1 in Healthy, Older Patients Admitted for Elective Hip or Knee Arthroplasty.
Weijzen MEG, Kouw IWK, Verschuren AAJ, Muyters R, Geurts JA, Emans PJ, Geerlings P, Verdijk LB, van Loon LJC. Weijzen MEG, et al. Among authors: verdijk lb. J Nutr Health Aging. 2019;23(3):299-305. doi: 10.1007/s12603-019-1157-2. J Nutr Health Aging. 2019. PMID: 30820520 Free PMC article.
CONCLUSIONS: Though self-selected hospital meals provide patients with ~0.8 gkg-1d-1 protein during short-term hospitalization, actual protein consumption falls well below 0.6 gkg-1d-1 with a large proportion (~32%) of the provided food being discarded. ...
CONCLUSIONS: Though self-selected hospital meals provide patients with ~0.8 gkg-1d-1 protein during short-term hospitalization, actua …
Dietary feeding pattern does not modulate the loss of muscle mass or the decline in metabolic health during short-term bed rest.
Dirks ML, Smeets JSJ, Holwerda AM, Kouw IWK, Marzuca-Nassr GN, Gijsen AP, Holloway GP, Verdijk LB, van Loon LJC. Dirks ML, et al. Among authors: verdijk lb. Am J Physiol Endocrinol Metab. 2019 Mar 1;316(3):E536-E545. doi: 10.1152/ajpendo.00378.2018. Epub 2019 Jan 15. Am J Physiol Endocrinol Metab. 2019. PMID: 30645176 Free article.
Creatine Loading Does Not Preserve Muscle Mass or Strength During Leg Immobilization in Healthy, Young Males: A Randomized Controlled Trial.
Backx EMP, Hangelbroek R, Snijders T, Verscheijden ML, Verdijk LB, de Groot LCPGM, van Loon LJC. Backx EMP, et al. Among authors: verdijk lb. Sports Med. 2017 Aug;47(8):1661-1671. doi: 10.1007/s40279-016-0670-2. Sports Med. 2017. PMID: 28054322 Free PMC article. Clinical Trial.
OBJECTIVE: Our objective was to investigate whether creatine loading can attenuate the loss of muscle mass and strength during short-term leg immobilization. METHODS: Healthy young men (n = 30; aged 23 1 years; body mass index [BMI] 23.3 0.5 kg/m(-2)) were randomly assigne …
OBJECTIVE: Our objective was to investigate whether creatine loading can attenuate the loss of muscle mass and strength during short-term
Short-term muscle disuse lowers myofibrillar protein synthesis rates and induces anabolic resistance to protein ingestion.
Wall BT, Dirks ML, Snijders T, van Dijk JW, Fritsch M, Verdijk LB, van Loon LJ. Wall BT, et al. Among authors: verdijk lb. Am J Physiol Endocrinol Metab. 2016 Jan 15;310(2):E137-47. doi: 10.1152/ajpendo.00227.2015. Epub 2015 Nov 17. Am J Physiol Endocrinol Metab. 2016. PMID: 26578714 Free article.
It has been hypothesized that short successive periods of muscle disuse throughout the lifespan play an important role in the development of sarcopenia. The physiological mechanisms underlying short-term muscle disuse atrophy remain to be elucidated. We assessed the impact …
It has been hypothesized that short successive periods of muscle disuse throughout the lifespan play an important role in the development of …
Skeletal muscle disuse atrophy is not attenuated by dietary protein supplementation in healthy older men.
Dirks ML, Wall BT, Nilwik R, Weerts DH, Verdijk LB, van Loon LJ. Dirks ML, et al. Among authors: verdijk lb. J Nutr. 2014 Aug;144(8):1196-203. doi: 10.3945/jn.114.194217. Epub 2014 Jun 11. J Nutr. 2014. PMID: 24919692 Free article. Clinical Trial.
In conclusion, dietary protein supplementation (20 g twice daily) does not attenuate muscle loss during short-term muscle disuse in healthy older men. This trial was registered at clinicaltrials.gov as NCT01588808....
In conclusion, dietary protein supplementation (20 g twice daily) does not attenuate muscle loss during short-term muscle disuse in h …
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