Skeletal muscle unloading results in increased mitophagy and decreased mitochondrial biogenesis regulation.
Leermakers PA, Kneppers AEM, Schols AMWJ, Kelders MCJM, de Theije CC, Verdijk LB, van Loon LJC, Langen RCJ, Gosker HR.
Leermakers PA, et al. Among authors: verdijk lb.
Muscle Nerve. 2019 Dec;60(6):769-778. doi: 10.1002/mus.26702. Epub 2019 Oct 23.
Muscle Nerve. 2019.
PMID: 31495926
Free PMC article.
METHODS: We analyzed a comprehensive set of molecular markers involved in mitochondrial-autophagy, -biogenesis, -dynamics, and -content, in the gastrocnemius muscle of C57BL/6J mice subjected to 0- and 3-days hind limb suspension, and in biopsies from human vastus lateralis muscl …
METHODS: We analyzed a comprehensive set of molecular markers involved in mitochondrial-autophagy, -biogenesis, -dynamics, and -content, in …