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Premature aging and reduced cancer incidence associated with near-complete body-wide Myc inactivation.
Wang H, Lu J, Stevens T, Roberts A, Mandel J, Avula R, Ma B, Wu Y, Wang J, Land CV, Finkel T, Vockley JE, Airik M, Airik R, Muzumdar R, Gong Z, Torbenson MS, Prochownik EV. Wang H, et al. Among authors: torbenson ms. Cell Rep. 2023 Aug 29;42(8):112830. doi: 10.1016/j.celrep.2023.112830. Epub 2023 Jul 22. Cell Rep. 2023. PMID: 37481724 Free PMC article.
Although Myc(+/-) mice are healthier and longer-lived than control mice, the long-term ramifications of more complete Myc loss remain unknown. We now describe the chronic consequences of body-wide Myc inactivation initiated postnatally. ...
Although Myc(+/-) mice are healthier and longer-lived than control mice, the long-term ramifications of more complete Myc loss remain …
Liver fibrosis quantification.
Venkatesh SK, Torbenson MS. Venkatesh SK, et al. Among authors: torbenson ms. Abdom Radiol (NY). 2022 Mar;47(3):1032-1052. doi: 10.1007/s00261-021-03396-y. Epub 2022 Jan 12. Abdom Radiol (NY). 2022. PMID: 35022806 Free PMC article. Review.
LF is the endpoint of chronic liver disease (CLD) regardless of etiology and the single most important determinant of long-term liver-related clinical outcomes. Quantification of LF is important for staging, to evaluate response to treatment and to predict outcomes. ...
LF is the endpoint of chronic liver disease (CLD) regardless of etiology and the single most important determinant of long-term liver …
Exercise Prevents Diet-Induced Cellular Senescence in Adipose Tissue.
Schafer MJ, White TA, Evans G, Tonne JM, Verzosa GC, Stout MB, Mazula DL, Palmer AK, Baker DJ, Jensen MD, Torbenson MS, Miller JD, Ikeda Y, Tchkonia T, van Deursen JM, Kirkland JL, LeBrasseur NK. Schafer MJ, et al. Among authors: torbenson ms. Diabetes. 2016 Jun;65(6):1606-15. doi: 10.2337/db15-0291. Epub 2016 Mar 16. Diabetes. 2016. PMID: 26983960 Free PMC article.
We show that exercise prevents the accumulation of senescent cells and the expression of the SASP while nullifying the damaging effects of the FFD on parameters of health. We also demonstrate that exercise initiated after long-term FFD feeding reduces senescent phenotype m …
We show that exercise prevents the accumulation of senescent cells and the expression of the SASP while nullifying the damaging effects of t …
Treatment of chronic hepatitis C: a systematic review.
Chander G, Sulkowski MS, Jenckes MW, Torbenson MS, Herlong HF, Bass EB, Gebo KA. Chander G, et al. Among authors: torbenson ms. Hepatology. 2002 Nov;36(5 Suppl 1):S135-44. doi: 10.1053/jhep.2002.37146. Hepatology. 2002. PMID: 12407587 Review.
This systematic review addressed 3 issues regarding current treatments for chronic hepatitis C: (1) efficacy and safety in treatment-naive patients; (2) efficacy and safety in selected subgroups of patients; and (3) effects on long-term clinical outcomes. Electronic databa …
This systematic review addressed 3 issues regarding current treatments for chronic hepatitis C: (1) efficacy and safety in treatment-naive p …