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1989 1
1994 2
1995 1
1998 1
2004 1
2006 1
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2008 1
2010 1
2012 1
2013 3
2014 2
2015 4
2016 2
2017 3
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2020 3
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2023 8
2024 3

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46 results

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Page 1
Omitting Radiotherapy after Breast-Conserving Surgery in Luminal A Breast Cancer.
Whelan TJ, Smith S, Parpia S, Fyles AW, Bane A, Liu FF, Rakovitch E, Chang L, Stevens C, Bowen J, Provencher S, Théberge V, Mulligan AM, Kos Z, Akra MA, Voduc KD, Hijal T, Dayes IS, Pond G, Wright JR, Nielsen TO, Levine MN; LUMINA Study Investigators. Whelan TJ, et al. N Engl J Med. 2023 Aug 17;389(7):612-619. doi: 10.1056/NEJMoa2302344. N Engl J Med. 2023. PMID: 37585627
However, radiotherapy is inconvenient, costly, and associated with both short-term and long-term side effects. Clinicopathologic factors alone are of limited use in the identification of women at low risk for local recurrence in whom radiotherapy can be omitted. ...
However, radiotherapy is inconvenient, costly, and associated with both short-term and long-term side effects. Clinicopatholog …
Edoxaban versus warfarin in patients with atrial fibrillation.
Giugliano RP, Ruff CT, Braunwald E, Murphy SA, Wiviott SD, Halperin JL, Waldo AL, Ezekowitz MD, Weitz JI, Špinar J, Ruzyllo W, Ruda M, Koretsune Y, Betcher J, Shi M, Grip LT, Patel SP, Patel I, Hanyok JJ, Mercuri M, Antman EM; ENGAGE AF-TIMI 48 Investigators. Giugliano RP, et al. N Engl J Med. 2013 Nov 28;369(22):2093-104. doi: 10.1056/NEJMoa1310907. Epub 2013 Nov 19. N Engl J Med. 2013. PMID: 24251359 Free article. Clinical Trial.
BACKGROUND: Edoxaban is a direct oral factor Xa inhibitor with proven antithrombotic effects. The long-term efficacy and safety of edoxaban as compared with warfarin in patients with atrial fibrillation is not known. ...
BACKGROUND: Edoxaban is a direct oral factor Xa inhibitor with proven antithrombotic effects. The long-term efficacy and safety of ed …
Association Between Acute Myocardial Infarction and Cognition.
Johansen MC, Ye W, Gross A, Gottesman RF, Han D, Whitney R, Briceño EM, Giordani BJ, Shore S, Elkind MSV, Manly JJ, Sacco RL, Fohner A, Griswold M, Psaty BM, Sidney S, Sussman J, Yaffe K, Moran AE, Heckbert S, Hughes TM, Galecki A, Levine DA. Johansen MC, et al. Among authors: sussman j. JAMA Neurol. 2023 Jul 1;80(7):723-731. doi: 10.1001/jamaneurol.2023.1331. JAMA Neurol. 2023. PMID: 37252710
The interaction analysis suggested that race and sex modified the degree of change in the decline in global cognition after MI (race post-MI slope interaction term, P = .02; sex post-MI slope interaction term, P = .04), with a smaller change in the decline over the …
The interaction analysis suggested that race and sex modified the degree of change in the decline in global cognition after MI (race post-MI …
Dulaglutide and renal outcomes in type 2 diabetes: an exploratory analysis of the REWIND randomised, placebo-controlled trial.
Gerstein HC, Colhoun HM, Dagenais GR, Diaz R, Lakshmanan M, Pais P, Probstfield J, Botros FT, Riddle MC, Rydén L, Xavier D, Atisso CM, Dyal L, Hall S, Rao-Melacini P, Wong G, Avezum A, Basile J, Chung N, Conget I, Cushman WC, Franek E, Hancu N, Hanefeld M, Holt S, Jansky P, Keltai M, Lanas F, Leiter LA, Lopez-Jaramillo P, Cardona Munoz EG, Pirags V, Pogosova N, Raubenheimer PJ, Shaw JE, Sheu WH, Temelkova-Kurktschiev T; REWIND Investigators. Gerstein HC, et al. Lancet. 2019 Jul 13;394(10193):131-138. doi: 10.1016/S0140-6736(19)31150-X. Epub 2019 Jun 9. Lancet. 2019. PMID: 31189509 Clinical Trial.
BACKGROUND: Two glucagon-like peptide-1 (GLP-1) receptor agonists reduced renal outcomes in people with type 2 diabetes at risk for cardiovascular disease. We assessed the long-term effect of the GLP-1 receptor agonist dulaglutide on renal outcomes in an exploratory analys …
BACKGROUND: Two glucagon-like peptide-1 (GLP-1) receptor agonists reduced renal outcomes in people with type 2 diabetes at risk for cardiova …
Evidence for in vitro extensive proliferation of adult hepatocytes and biliary epithelial cells.
Katsuda T, Sussman J, Li J, Merrell AJ, Vostrejs W, Secreto A, Matsuzaki J, Ochiya T, Stanger BZ. Katsuda T, et al. Among authors: sussman j. Stem Cell Reports. 2023 Jul 11;18(7):1436-1450. doi: 10.1016/j.stemcr.2023.05.016. Epub 2023 Jun 22. Stem Cell Reports. 2023. PMID: 37352852 Free PMC article.
Unexpectedly, we also found that the CLiP method allows biliary epithelial cells to acquire extensive proliferative capacity. Interestingly, after long-term culture, hepatocyte-derived cells (hepCLiPs) and biliary epithelial cell-derived cells (bilCLiPs) become similar in …
Unexpectedly, we also found that the CLiP method allows biliary epithelial cells to acquire extensive proliferative capacity. Interestingly, …
Long-term outcomes and effects of hypofractionated radiotherapy in microinvasive breast cancer: Analysis from a randomized trial.
Goldberg M, Parpia S, Rakovitch E, Chang L, Bowen J, Lukka H, Perera F, Fyles A, Wright J, Sussman J, Whelan T. Goldberg M, et al. Among authors: sussman j. Breast. 2023 Apr;68:189-193. doi: 10.1016/j.breast.2023.02.005. Epub 2023 Feb 10. Breast. 2023. PMID: 36827900 Free PMC article. Clinical Trial.
PURPOSE: The natural history of microinvasive (T1mi) breast cancer is uncertain. The objective was to evaluate long-term local and distant recurrence rates following breast conserving surgery (BCS) in a prospective cohort of patients with T1mi compared to T1a-2 disease who …
PURPOSE: The natural history of microinvasive (T1mi) breast cancer is uncertain. The objective was to evaluate long-term local and di …
Self-Reported Everyday Functioning After COVID-19 Infection.
Iwashyna TJ, Smith VA, Seelye S, Bohnert ASB, Boyko EJ, Hynes DM, Ioannou GN, Maciejewski ML, O'Hare AM, Viglianti EM, Berkowitz TS, Pura J, Womer J, Kamphuis LA, Monahan ML, Bowling CB; VA HSR&D COVID-19 Observational Research Collaboratory (CORC). Iwashyna TJ, et al. JAMA Netw Open. 2024 Mar 4;7(3):e240869. doi: 10.1001/jamanetworkopen.2024.0869. JAMA Netw Open. 2024. PMID: 38427352 Free PMC article.
IMPORTANCE: Changes in everyday functioning are crucial to assessing the long-term impact of COVID-19 infection. OBJECTIVE: To examine the impact of COVID-19 infection on everyday functioning 18 months after infection among veterans with and without histories of COVID-19 i …
IMPORTANCE: Changes in everyday functioning are crucial to assessing the long-term impact of COVID-19 infection. OBJECTIVE: To examin …
Long-term effect of thymectomy plus prednisone versus prednisone alone in patients with non-thymomatous myasthenia gravis: 2-year extension of the MGTX randomised trial.
Wolfe GI, Kaminski HJ, Aban IB, Minisman G, Kuo HC, Marx A, Ströbel P, Mazia C, Oger J, Cea JG, Heckmann JM, Evoli A, Nix W, Ciafaloni E, Antonini G, Witoonpanich R, King JO, Beydoun SR, Chalk CH, Barboi AC, Amato AA, Shaibani AI, Katirji B, Lecky BRF, Buckley C, Vincent A, Dias-Tosta E, Yoshikawa H, Waddington-Cruz M, Pulley MT, Rivner MH, Kostera-Pruszczyk A, Pascuzzi RM, Jackson CE, Verschuuren JJGM, Massey JM, Kissel JT, Werneck LC, Benatar M, Barohn RJ, Tandan R, Mozaffar T, Silvestri NJ, Conwit R, Sonett JR, Jaretzki A 3rd, Newsom-Davis J, Cutter GR; MGTX Study Group. Wolfe GI, et al. Lancet Neurol. 2019 Mar;18(3):259-268. doi: 10.1016/S1474-4422(18)30392-2. Epub 2019 Jan 25. Lancet Neurol. 2019. PMID: 30692052 Free PMC article. Clinical Trial.
BACKGROUND: The Thymectomy Trial in Non-Thymomatous Myasthenia Gravis Patients Receiving Prednisone (MGTX) showed that thymectomy combined with prednisone was superior to prednisone alone in improving clinical status as measured by the Quantitative Myasthenia Gravis (QMG) score i …
BACKGROUND: The Thymectomy Trial in Non-Thymomatous Myasthenia Gravis Patients Receiving Prednisone (MGTX) showed that thymectomy combined w …
What's in a name? Why these proteins are intrinsically disordered: Why these proteins are intrinsically disordered.
Dunker AK, Babu MM, Barbar E, Blackledge M, Bondos SE, Dosztányi Z, Dyson HJ, Forman-Kay J, Fuxreiter M, Gsponer J, Han KH, Jones DT, Longhi S, Metallo SJ, Nishikawa K, Nussinov R, Obradovic Z, Pappu RV, Rost B, Selenko P, Subramaniam V, Sussman JL, Tompa P, Uversky VN. Dunker AK, et al. Among authors: sussman jl. Intrinsically Disord Proteins. 2013 Apr 1;1(1):e24157. doi: 10.4161/idp.24157. eCollection 2013 Jan-Dec. Intrinsically Disord Proteins. 2013. PMID: 28516007 Free PMC article. Review.
We start from the beginning, namely from the explanation of what the expression "intrinsically disordered protein" actually means and why this particular term has been chosen as the common denominator for this class of proteins characterized by broad structural, dynamic an …
We start from the beginning, namely from the explanation of what the expression "intrinsically disordered protein" actually means and why th …
Activation of T lymphocytes for the adoptive immunotherapy of cancer.
Sussman JJ, Shu S, Sondak VK, Chang AE. Sussman JJ, et al. Ann Surg Oncol. 1994 Jul;1(4):296-306. doi: 10.1007/BF02303568. Ann Surg Oncol. 1994. PMID: 7850528 Free article. Review.
Based on animal models, the transfer of immune lymphoid cells can eradicate widely disseminated tumors and establish long-term systemic immunity. Critical for successful adoptive immunotherapy is the ability to isolate large numbers of immune cells. ...
Based on animal models, the transfer of immune lymphoid cells can eradicate widely disseminated tumors and establish long-term system …
46 results