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Page 1
Anticoagulant-associated gastrointestinal bleeding: Framework for decisions about whether, when and how to resume anticoagulants.
Xu Y, Siegal DM. Xu Y, et al. Among authors: siegal dm. J Thromb Haemost. 2021 Oct;19(10):2383-2393. doi: 10.1111/jth.15466. Epub 2021 Jul 29. J Thromb Haemost. 2021. PMID: 34273241 Free article. Review.
Patients with major GI bleeding experience morbidity and a substantial risk of short-term all-cause mortality up to 10%. While OACs are frequently discontinued during acute bleeding, there is substantial uncertainty about whether, when, and how OACs should be resumed after …
Patients with major GI bleeding experience morbidity and a substantial risk of short-term all-cause mortality up to 10%. While OACs a …
Role of statins in the prevention of post-thrombotic syndrome after a deep vein thrombosis event: a systematic review and meta-analysis.
Caiano LM, Drury T, Zahrai A, Wang TF, Siegal DM, Rodger MA, Fournier K, Delluc A. Caiano LM, et al. Among authors: siegal dm. J Thromb Haemost. 2023 Apr;21(4):944-952. doi: 10.1016/j.jtha.2022.12.008. Epub 2022 Dec 22. J Thromb Haemost. 2023. PMID: 36696186
BACKGROUND: Post-thrombotic syndrome (PTS) is the most frequent long-term complication of deep vein thrombosis. Apart from anticoagulation, there are no medications, procedures, devices, or lifestyle changes that effectively prevent PTS. ...
BACKGROUND: Post-thrombotic syndrome (PTS) is the most frequent long-term complication of deep vein thrombosis. Apart from anticoagul …
Direct oral anticoagulants versus vitamin K antagonists in the first 3 months after bioprosthetic valve replacement: a systematic review and meta-analysis.
Eikelboom R, Whitlock RP, Muzaffar R, Lopes RD, Siegal D, Schulman S, Belley-Côté EP. Eikelboom R, et al. Among authors: siegal d. Eur J Cardiothorac Surg. 2023 Apr 3;63(4):ezad110. doi: 10.1093/ejcts/ezad110. Eur J Cardiothorac Surg. 2023. PMID: 36971601
Future studies should focus on surgical valves and should include long-term follow-up to assess any potential impact of randomized therapy on valve durability....
Future studies should focus on surgical valves and should include long-term follow-up to assess any potential impact of randomized th …
Periprocedural heparin bridging in patients receiving vitamin K antagonists: systematic review and meta-analysis of bleeding and thromboembolic rates.
Siegal D, Yudin J, Kaatz S, Douketis JD, Lim W, Spyropoulos AC. Siegal D, et al. Circulation. 2012 Sep 25;126(13):1630-9. doi: 10.1161/CIRCULATIONAHA.112.105221. Epub 2012 Aug 21. Circulation. 2012. PMID: 22912386 Review.
BACKGROUND: Periprocedural bridging with unfractionated heparin or low-molecular-weight heparin aims to reduce the risk of thromboembolic events in patients receiving long-term vitamin K antagonists. Optimal periprocedural anticoagulation has not been established. ...
BACKGROUND: Periprocedural bridging with unfractionated heparin or low-molecular-weight heparin aims to reduce the risk of thromboembolic ev …
What we have learned about direct oral anticoagulant reversal.
Siegal DM. Siegal DM. Hematology Am Soc Hematol Educ Program. 2019 Dec 6;2019(1):198-203. doi: 10.1182/hematology.2019000072. Hematology Am Soc Hematol Educ Program. 2019. PMID: 31808835 Free PMC article.
Importantly, patients with DOAC-related major bleeding have substantial short-term risks of thrombosis and mortality, emphasizing the need for individualized patient assessment and protocolized bleed management strategies that include assessment of candidacy for safe resum …
Importantly, patients with DOAC-related major bleeding have substantial short-term risks of thrombosis and mortality, emphasizing the …
Management of bleeding risk in patients who receive anticoagulant therapy for venous thromboembolism: Communication from the ISTH SSC Subcommittee on Predictive and Diagnostic Variables in Thrombotic Disease.
den Exter PL, Woller SC, Robert-Ebadi H, Masias C, Morange PE, Castelli D, Hansen JB, Geersing GJ, Siegal DM, de Wit K, Klok FA. den Exter PL, et al. Among authors: siegal dm. J Thromb Haemost. 2022 Aug;20(8):1910-1919. doi: 10.1111/jth.15776. Epub 2022 Jun 23. J Thromb Haemost. 2022. PMID: 35735219 Free PMC article.
Identification of patients at high risk of bleeding, and mitigating this risk, is an essential component of the immediate and long-term therapeutic management of VTE. The bleeding risk can be estimated by either implicit judgment, weighing individual predictors (clinical v …
Identification of patients at high risk of bleeding, and mitigating this risk, is an essential component of the immediate and long-term …
Association Between Years of Competition and Shoulder Function in Collegiate Swimmers.
Dischler JD, Baumer TG, Finkelstein E, Siegal DS, Bey MJ. Dischler JD, et al. Among authors: siegal ds. Sports Health. 2018 Mar/Apr;10(2):113-118. doi: 10.1177/1941738117726771. Epub 2017 Aug 22. Sports Health. 2018. PMID: 28829699 Free PMC article.
Shoulder strength was not associated with years of participation ( P > 0.39). CONCLUSION: Long-term competitive swim training is associated with declining measures of supraspinatus muscle/tendon properties and self-reported measures of pain and function. ...
Shoulder strength was not associated with years of participation ( P > 0.39). CONCLUSION: Long-term competitive swim training is a …
Perioperative covert stroke in patients undergoing non-cardiac surgery (NeuroVISION): a prospective cohort study.
NeuroVISION Investigators. NeuroVISION Investigators. Lancet. 2019 Sep 21;394(10203):1022-1029. doi: 10.1016/S0140-6736(19)31795-7. Epub 2019 Aug 15. Lancet. 2019. PMID: 31422895
FUNDING: Canadian Institutes of Health Research; The Ontario Strategy for Patient Oriented Research support unit; The Ontario Ministry of Health and Long-Term Care; Health and Medical Research Fund, Government of the Hong Kong Special Administrative Region, China; and The …
FUNDING: Canadian Institutes of Health Research; The Ontario Strategy for Patient Oriented Research support unit; The Ontario Ministry of He …