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Effects of Exercise Training Response on Quality of Life and Cardiovascular Risk Factor Profiles in People With Coronary Artery Disease: Insights From the HIIT or MISS UK Trial.
Ingle L, Powell R, Begg B, Birkett ST, Nichols S, Ennis S, Banerjee P, Shave R, McGregor G. Ingle L, et al. Among authors: shave r. Arch Phys Med Rehabil. 2024 Mar 16:S0003-9993(24)00883-9. doi: 10.1016/j.apmr.2024.03.002. Online ahead of print. Arch Phys Med Rehabil. 2024. PMID: 38493909
In people with CAD attending CR, the HIIT or MISS UK trial reported that short-term, low-volume, high-intensity interval training (HIIT) was more effective than moderate-intensity steady state (MISS) exercise training for improving peak oxygen uptake (Vo(2)peak). ...
In people with CAD attending CR, the HIIT or MISS UK trial reported that short-term, low-volume, high-intensity interval training (HI …
High-intensity interval training in cardiac rehabilitation: a multi-centre randomized controlled trial.
McGregor G, Powell R, Begg B, Birkett ST, Nichols S, Ennis S, McGuire S, Prosser J, Fiassam O, Hee SW, Hamborg T, Banerjee P, Hartfiel N, Charles JM, Edwards RT, Drane A, Ali D, Osman F, He H, Lachlan T, Haykowsky MJ, Ingle L, Shave R. McGregor G, et al. Among authors: shave r. Eur J Prev Cardiol. 2023 Jul 12;30(9):745-755. doi: 10.1093/eurjpc/zwad039. Eur J Prev Cardiol. 2023. PMID: 36753063 Clinical Trial.
Low-volume HIIT is a safe, well-tolerated, and clinically effective intervention that produces short-term improvement in cardiorespiratory fitness. It should be considered by all CR programmes as an adjunct or alternative to MISS. ...
Low-volume HIIT is a safe, well-tolerated, and clinically effective intervention that produces short-term improvement in cardiorespir …
Protective effects of acute exercise prior to doxorubicin on cardiac function of breast cancer patients: A proof-of-concept RCT.
Kirkham AA, Shave RE, Bland KA, Bovard JM, Eves ND, Gelmon KA, McKenzie DC, Virani SA, Stöhr EJ, Warburton DER, Campbell KL. Kirkham AA, et al. Among authors: shave re. Int J Cardiol. 2017 Oct 15;245:263-270. doi: 10.1016/j.ijcard.2017.07.037. Epub 2017 Jul 14. Int J Cardiol. 2017. PMID: 28735755 Clinical Trial.
CONCLUSION: The first doxorubicin treatment is associated with acutely increased NT-proBNP, echocardiographic parameters of myocardial relaxation, left ventricular volume overload, and changes in longitudinal strain and twist opposite in direction to documented longer-term …
CONCLUSION: The first doxorubicin treatment is associated with acutely increased NT-proBNP, echocardiographic parameters of myocardial relax …
Cardiac dysfunction in cancer survivors unmasked during exercise.
Kearney MC, Gallop-Evans E, Cockcroft JR, Stöhr EJ, Lee E, Backx K, Haykowsky M, Yousef Z, Shave R. Kearney MC, et al. Among authors: shave r. Eur J Clin Invest. 2017 Mar;47(3):213-220. doi: 10.1111/eci.12720. Epub 2017 Jan 30. Eur J Clin Invest. 2017. PMID: 28036108
The purpose of the present cross-sectional study was to determine whether the combination of these techniques could be used to improve the characterisation of subclinical CV dysfunction in long-term cancer survivors previously treated with anthracyclines. MATERIALS AND MET …
The purpose of the present cross-sectional study was to determine whether the combination of these techniques could be used to improve the c …
Short-term adaptation and chronic cardiac remodelling to high altitude in lowlander natives and Himalayan Sherpa.
Stembridge M, Ainslie PN, Shave R. Stembridge M, et al. Among authors: shave r. Exp Physiol. 2015 Nov;100(11):1242-6. doi: 10.1113/expphysiol.2014.082503. Epub 2014 Nov 20. Exp Physiol. 2015. PMID: 26575341 Free article. Review.
At high altitude, the cardiovascular system must adapt in order to meet the metabolic demand for oxygen. This review summarizes recent findings relating to short-term and life-long cardiac adaptation to high altitude in the context of exercise capacity. ...Both short-te …
At high altitude, the cardiovascular system must adapt in order to meet the metabolic demand for oxygen. This review summarizes recent findi …
Ventricular structure, function, and mechanics at high altitude: chronic remodeling in Sherpa vs. short-term lowlander adaptation.
Stembridge M, Ainslie PN, Hughes MG, Stöhr EJ, Cotter JD, Nio AQ, Shave R. Stembridge M, et al. Among authors: shave r. J Appl Physiol (1985). 2014 Aug 1;117(3):334-43. doi: 10.1152/japplphysiol.00233.2014. Epub 2014 May 29. J Appl Physiol (1985). 2014. PMID: 24876358 Free PMC article.
Short-term, high-altitude (HA) exposure raises pulmonary artery systolic pressure (PASP) and decreases left-ventricular (LV) volumes. However, relatively little is known of the long-term cardiac consequences of prolonged exposure in Sherpa, a highly adapted HA popul …
Short-term, high-altitude (HA) exposure raises pulmonary artery systolic pressure (PASP) and decreases left-ventricular (LV) volumes. …
Exercise and the heart: can you have too much of a good thing?
George K, Shave R, Warburton D, Scharhag J, Whyte G. George K, et al. Among authors: shave r. Med Sci Sports Exerc. 2008 Aug;40(8):1390-2. doi: 10.1249/MSS.0b013e318172ceec. Med Sci Sports Exerc. 2008. PMID: 18614955
Further, the mechanisms underpinning these events are not clear. Finally, a clear message related to the short- and the long-term impact on cardiovascular health and/or sports performance is lacking. ...
Further, the mechanisms underpinning these events are not clear. Finally, a clear message related to the short- and the long-term imp …
Post-mortem evidence of idiopathic left ventricular hypertrophy and idiopathic interstitial myocardial fibrosis: is exercise the cause?
Whyte G, Sheppard M, George K, Shave R, Wilson M, Prasad S, O'Hanlon R, Sharma S. Whyte G, et al. Among authors: shave r. Br J Sports Med. 2008 Apr;42(4):304-5. doi: 10.1136/bjsm.2007.038158. Epub 2007 Aug 24. Br J Sports Med. 2008. PMID: 17720799
A growing body of evidence reporting altered cardiac function and myocardial damage after arduous exercise, together with the increased prevalence of arrhythmias observed in highly trained athletes, suggests that repetitive bouts of prolonged, arduous exercise may be deleterious …
A growing body of evidence reporting altered cardiac function and myocardial damage after arduous exercise, together with the increased prev …
Impact of repeated prolonged exercise bouts on cardiac function and biomarkers.
Middleton N, Shave R, George K, Whyte G, Simpson R, Florida-James G, Gaze D. Middleton N, et al. Among authors: shave r. Med Sci Sports Exerc. 2007 Jan;39(1):83-90. doi: 10.1249/01.mss.0000239395.93578.60. Med Sci Sports Exerc. 2007. PMID: 17218888
CONCLUSION: Repeated bouts of prolonged exercise induce short-term reductions in diastolic filling and a cumulative decrease in systolic function, yet these alterations seem to have minimal clinical or functional impact. ...
CONCLUSION: Repeated bouts of prolonged exercise induce short-term reductions in diastolic filling and a cumulative decrease in systo …
Left ventricular function immediately following prolonged exercise: A meta-analysis.
Middleton N, Shave R, George K, Whyte G, Hart E, Atkinson G. Middleton N, et al. Among authors: shave r. Med Sci Sports Exerc. 2006 Apr;38(4):681-7. doi: 10.1249/01.mss.0000210203.10200.12. Med Sci Sports Exerc. 2006. PMID: 16679983
The purpose of this meta-analysis was to quantify all data fulfilling the specified inclusion criteria, examining the short-term effect of prolonged endurance exercise on left ventricular function. ...
The purpose of this meta-analysis was to quantify all data fulfilling the specified inclusion criteria, examining the short-term effe …