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Ceftriaxone to prevent early ventilator-associated pneumonia in patients with acute brain injury: a multicentre, randomised, double-blind, placebo-controlled, assessor-masked superiority trial.
Dahyot-Fizelier C, Lasocki S, Kerforne T, Perrigault PF, Geeraerts T, Asehnoune K, Cinotti R, Launey Y, Cottenceau V, Laffon M, Gaillard T, Boisson M, Aleyrat C, Frasca D, Mimoz O; PROPHY-VAP Study Group and the ATLANREA Study Group. Dahyot-Fizelier C, et al. Lancet Respir Med. 2024 May;12(5):375-385. doi: 10.1016/S2213-2600(23)00471-X. Epub 2024 Jan 20. Lancet Respir Med. 2024. PMID: 38262428 Clinical Trial.
BACKGROUND: Patients with acute brain injury are at high risk of ventilator-associated pneumonia (VAP). The benefit of short-term antibiotic prophylaxis remains debated. We aimed to establish the effect of an early, single dose of the antibiotic ceftriaxone on the incidenc …
BACKGROUND: Patients with acute brain injury are at high risk of ventilator-associated pneumonia (VAP). The benefit of short-term ant …
Long-Term Outcome of Severe Metabolic Acidemia in ICU Patients, a BICAR-ICU Trial Post Hoc Analysis.
Bendiab E, Garnier F, Soler M, Fosset M, Jaber S, Molinari N, Jung B; BICAR-ICU Investigators. Bendiab E, et al. Crit Care Med. 2023 Jan 1;51(1):e1-e12. doi: 10.1097/CCM.0000000000005706. Epub 2022 Nov 8. Crit Care Med. 2023. PMID: 36351174 Clinical Trial.
OBJECTIVES: Long-term prognosis of ICU survivors is a major issue. Severe acidemia upon ICU admission is associated with very high short-term mortality. Since the long-term prognosis of these patients is unknown, we aimed to determine the long-term hea …
OBJECTIVES: Long-term prognosis of ICU survivors is a major issue. Severe acidemia upon ICU admission is associated with very high sh …
Anxiety and depression symptoms in relatives of moderate-to-severe traumatic brain injury survivors - A multicentre cohort.
Cinotti R, Chopin A, Moyer JD, Huet O, Lasocki S, Cohen B, Dahyot-Fizelier C, Chalard K, Seguin P, Martin FP, Lerebourg C, Guitteny M, Chenet A, Perrouin-Verbe B, Asehnoune K, Feuillet F, Sébille V, Roquilly A; Atlanréa Group and the Société Française d’Anesthésie-Réanimation–SFAR Research Network. Cinotti R, et al. Among authors: seguin p. Anaesth Crit Care Pain Med. 2023 Oct;42(5):101232. doi: 10.1016/j.accpm.2023.101232. Epub 2023 Apr 11. Anaesth Crit Care Pain Med. 2023. PMID: 37054915 Clinical Trial.
Anxiety and depression were inversely correlated with the patient's mental health status at 6 months. CONCLUSIONS: Long-term follow-up must provide psychological care to relatives after TBI....
Anxiety and depression were inversely correlated with the patient's mental health status at 6 months. CONCLUSIONS: Long-term follow-u …
Liver Dysfunction Is Associated with Long-Term Mortality in Septic Shock.
Nesseler N, Launey Y, Aninat C, White J, Corlu A, Pieper K, Mallédant Y, Seguin P. Nesseler N, et al. Among authors: seguin p. Am J Respir Crit Care Med. 2016 Feb 1;193(3):335-7. doi: 10.1164/rccm.201508-1660LE. Am J Respir Crit Care Med. 2016. PMID: 26829424 No abstract available.
[Impact of age on mortality in patients with acute traumatic spinal cord injury requiring intensive care].
Seguin P, Godard A, Le Maguet P, Launey Y, Laviolle B, Mallédant Y. Seguin P, et al. Ann Fr Anesth Reanim. 2012 Mar;31(3):196-202. doi: 10.1016/j.annfar.2011.10.019. Epub 2011 Dec 26. Ann Fr Anesth Reanim. 2012. PMID: 22204755 French.
Intensive care unit (ICU) discharge and long-term neurological recovery, and long-term functional independence measure (FIM) were assessed. ...Among survivors, incompletes forms (Frankel B, C, D, E) were significantly more frequent in older patients at ICU discharge …
Intensive care unit (ICU) discharge and long-term neurological recovery, and long-term functional independence measure (FIM) w …
Long-term mortality and quality of life after septic shock: a follow-up observational study.
Nesseler N, Defontaine A, Launey Y, Morcet J, Mallédant Y, Seguin P. Nesseler N, et al. Among authors: seguin p. Intensive Care Med. 2013 May;39(5):881-8. doi: 10.1007/s00134-013-2815-1. Epub 2013 Jan 29. Intensive Care Med. 2013. PMID: 23358541
PURPOSE: In septic shock, short-term outcomes are frequently reported, while long-term outcomes are not. ...
PURPOSE: In septic shock, short-term outcomes are frequently reported, while long-term outcomes are not. ...
Risk factors for prolonged duration of mechanical ventilation in acute traumatic tetraplegic patients--a retrospective cohort study.
Roquilly A, Seguin P, Mimoz O, Feuillet F, Rosenczweig E, Chevalier F, Loutrel O, Malledant Y, Sebille V, Asehnoune K; ATLANREA Study Group. Roquilly A, et al. Among authors: seguin p. J Crit Care. 2014 Apr;29(2):313.e7-13. doi: 10.1016/j.jcrc.2013.11.021. Epub 2013 Dec 2. J Crit Care. 2014. PMID: 24412010
In a population of tetraplegic patients, we investigated the factors involved in the duration of mechanical ventilation (MV) and whether the duration of MV was associated with the long-term neurologic status. MATERIAL AND METHODS: In a retrospective study in 3 intensive ca …
In a population of tetraplegic patients, we investigated the factors involved in the duration of mechanical ventilation (MV) and whether the …
Corticotherapy for traumatic brain-injured patients--the Corti-TC trial: study protocol for a randomized controlled trial.
Asehnoune K, Roquilly A, Sebille V; Corti-TC trial group. Asehnoune K, et al. Trials. 2011 Oct 14;12:228. doi: 10.1186/1745-6215-12-228. Trials. 2011. PMID: 21999663 Free PMC article. Clinical Trial.
DISCUSSION: The CORTI-TC trial is the first randomized controlled trial powered to investigate whether hydrocortisone with fludrocortisone in TBI patients with CI prevent HAP and improve long term recovery. TRIAL REGISTRATION: NCT01093261....
DISCUSSION: The CORTI-TC trial is the first randomized controlled trial powered to investigate whether hydrocortisone with fludrocortisone i …
COBI (COntinuous hyperosmolar therapy for traumatic Brain-Injured patients) trial protocol: a multicentre randomised open-label trial with blinded adjudication of primary outcome.
Roquilly A, Lasocki S, Moyer JD, Huet O, Perrigault PF, Dahyot-Fizelier C, Seguin P, Sharshar T, Geeraerts T, Remerand F, Feuillet F, Asehnoune K; COBI group. Roquilly A, et al. Among authors: seguin p. BMJ Open. 2017 Sep 24;7(9):e018035. doi: 10.1136/bmjopen-2017-018035. BMJ Open. 2017. PMID: 28947465 Free PMC article. Clinical Trial.
Whether an early administration of continuous hyperosmolar therapy improves long-term outcomes of patients with TBI is uncertain. The aim of the COBI study (number clinicaltrial.gov 03143751, pre-results stage) is to assess the efficiency and the safety of continuous hyper …
Whether an early administration of continuous hyperosmolar therapy improves long-term outcomes of patients with TBI is uncertain. The …
16 results