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Impact of additional genetic abnormalities at diagnosis of chronic myeloid leukemia for first-line imatinib-treated patients receiving proactive treatment intervention.
Shanmuganathan N, Wadham C, Shahrin N, Feng J, Thomson D, Wang P, Saunders V, Kok CH, King RM, Kenyon RR, Lin M, Pagani IS, Ross DM, Yong ASM, Grigg AP, Mills AK, Schwarer AP, Braley J, Altamura H, Yeung DT, Scott HS, Schreiber AW, Hughes TP, Branford S. Shanmuganathan N, et al. Among authors: scott hs. Haematologica. 2023 Sep 1;108(9):2380-2395. doi: 10.3324/haematol.2022.282184. Haematologica. 2023. PMID: 36951160 Free PMC article.
Multivariable analysis demonstrated that the combined genetic abnormalities plus the EUTOS long-term survival clinical risk score were independent predictors of lower molecular response rates and higher treatment failure. ...
Multivariable analysis demonstrated that the combined genetic abnormalities plus the EUTOS long-term survival clinical risk score wer …
Cancer and Central Nervous System Tumor Surveillance in Pediatric Neurofibromatosis 1.
Evans DGR, Salvador H, Chang VY, Erez A, Voss SD, Schneider KW, Scott HS, Plon SE, Tabori U. Evans DGR, et al. Among authors: scott hs. Clin Cancer Res. 2017 Jun 15;23(12):e46-e53. doi: 10.1158/1078-0432.CCR-17-0589. Clin Cancer Res. 2017. PMID: 28620004 Review.
A single whole-body MRI should be considered at transition to adulthood to assist in determining approaches to long-term follow-up. Clin Cancer Res; 23(12); e46-e53. 2017 AACRSee all articles in the online-only CCR Pediatric Oncology Series....
A single whole-body MRI should be considered at transition to adulthood to assist in determining approaches to long-term follow-up. C …
Recommendations for Surveillance for Children with Leukemia-Predisposing Conditions.
Porter CC, Druley TE, Erez A, Kuiper RP, Onel K, Schiffman JD, Wolfe Schneider K, Scollon SR, Scott HS, Strong LC, Walsh MF, Nichols KE. Porter CC, et al. Among authors: scott hs. Clin Cancer Res. 2017 Jun 1;23(11):e14-e22. doi: 10.1158/1078-0432.CCR-17-0428. Clin Cancer Res. 2017. PMID: 28572263 Review.
The development of registries and clinical trials is urgently needed to enhance understanding of the natural history of the leukemia-predisposing conditions, such that these surveillance recommendations can be optimized to further enhance long-term outcomes. Clin Cancer Re …
The development of registries and clinical trials is urgently needed to enhance understanding of the natural history of the leukemia-predisp …
Spatiotemporal regulation of multiple overlapping sense and novel natural antisense transcripts at the Nrgn and Camk2n1 gene loci during mouse cerebral corticogenesis.
Ling KH, Hewitt CA, Beissbarth T, Hyde L, Cheah PS, Smyth GK, Tan SS, Hahn CN, Thomas T, Thomas PQ, Scott HS. Ling KH, et al. Among authors: scott hs. Cereb Cortex. 2011 Mar;21(3):683-97. doi: 10.1093/cercor/bhq141. Epub 2010 Aug 6. Cereb Cortex. 2011. PMID: 20693275
Nrgn and Camk2n1 are highly expressed in the brain and play an important role in synaptic long-term potentiation via regulation of Ca(2+)/calmodulin-dependent protein kinase II. ...
Nrgn and Camk2n1 are highly expressed in the brain and play an important role in synaptic long-term potentiation via regulation of Ca …
Short-term inhibition of p53 combined with keratinocyte growth factor improves thymic epithelial cell recovery and enhances T-cell reconstitution after murine bone marrow transplantation.
Kelly RM, Goren EM, Taylor PA, Mueller SN, Stefanski HE, Osborn MJ, Scott HS, Komarova EA, Gudkov AV, Holländer GA, Blazar BR. Kelly RM, et al. Among authors: scott hs. Blood. 2010 Feb 4;115(5):1088-97. doi: 10.1182/blood-2009-05-223198. Epub 2009 Dec 4. Blood. 2010. PMID: 19965631 Free PMC article.
Long-term correction of albumin levels in the Nagase analbuminemic rat: repopulation of the liver by transplanted normal hepatocytes under a regeneration response.
Moscioni AD, Rozga J, Chen S, Naim A, Scott HS, Demetriou AA. Moscioni AD, et al. Among authors: scott hs. Cell Transplant. 1996 Jul-Aug;5(4):499-503. doi: 10.1177/096368979600500409. Cell Transplant. 1996. PMID: 8800518
Numerous studies have reported successful transplantation of hepatocytes with demonstration of function. However, none have shown long-term correction of a liver-related metabolic defect. Male Nagase analbuminemic rats, immunosuppressed with cyclosporin-A, were transplante …
Numerous studies have reported successful transplantation of hepatocytes with demonstration of function. However, none have shown long-te …