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Impact of the COVID-19 pandemic on daily life, mood, and behavior of adults with Down syndrome.
Hartley SL, Fleming V, Piro-Gambetti B, Cohen A, Ances BM, Yassa MA, Brickman AM, Handen BL, Head E, Mapstone M, Christian BT, Lott IT, Doran E, Zaman S, Krinsky-McHale S, Schmitt FA, Hom C, Schupf N; ABC-DS Group. Hartley SL, et al. Among authors: schupf n. Disabil Health J. 2022 Jul;15(3):101278. doi: 10.1016/j.dhjo.2022.101278. Epub 2022 Feb 17. Disabil Health J. 2022. PMID: 35256308 Free PMC article.
CONCLUSIONS: The COVID-19 pandemic has had widespread effects on the daily life and mood and behavior of adults with Down syndrome. In the short term, caregivers and providers should be prepared to help adults with Down syndrome with changes in daily routines, residence, e …
CONCLUSIONS: The COVID-19 pandemic has had widespread effects on the daily life and mood and behavior of adults with Down syndrome. In the s …
Association of Dietary Prebiotic Consumption with Reduced Risk of Alzheimer's Disease in a Multiethnic Population.
Nishikawa M, Brickman AM, Manly JJ, Schupf N, Mayeux RP, Gu Y. Nishikawa M, et al. Among authors: schupf n. Curr Alzheimer Res. 2021;18(12):984-992. doi: 10.2174/1567205019666211222115142. Curr Alzheimer Res. 2021. PMID: 34951365 Free PMC article.
Effect modification by race/ethnicity, APOE genotype, and gender was tested by including an interaction term into the Cox models, as well as by stratified analyses. RESULTS: Among 1,837 participants (1,263 women [69%]; mean [SD] age = 76 [6.3] years), there were 391 incide …
Effect modification by race/ethnicity, APOE genotype, and gender was tested by including an interaction term into the Cox models, as …
Association Between APOE Alleles and Change of Neuropsychological Tests in the Long Life Family Study.
Du M, Andersen SL, Schupf N, Feitosa MF, Barker MS, Perls TT, Sebastiani P. Du M, et al. Among authors: schupf n. J Alzheimers Dis. 2021;79(1):117-125. doi: 10.3233/JAD-201113. J Alzheimers Dis. 2021. PMID: 33216038 Free PMC article.
Six longitudinally collected neuropsychological test scores were modelled as a function of age at enrollment, follow-up time, gender, education, field center, birth cohort indicator (1935, or >1935), and the number of copies of e2 or e4 alleles. ...
Six longitudinally collected neuropsychological test scores were modelled as a function of age at enrollment, follow-up time, gender, educat …
Long-term exposure to air pollution and trajectories of cognitive decline among older adults.
Kulick ER, Wellenius GA, Boehme AK, Joyce NR, Schupf N, Kaufman JD, Mayeux R, Sacco RL, Manly JJ, Elkind MSV. Kulick ER, et al. Among authors: schupf n. Neurology. 2020 Apr 28;94(17):e1782-e1792. doi: 10.1212/WNL.0000000000009314. Epub 2020 Apr 8. Neurology. 2020. PMID: 32269113 Free PMC article.
OBJECTIVE: To evaluate the association between long-term exposure to ambient air pollution and cognitive decline in older adults residing in an urban area. ...
OBJECTIVE: To evaluate the association between long-term exposure to ambient air pollution and cognitive decline in older adults resi …
Long-term exposure to ambient air pollution, APOE-epsilon4 status, and cognitive decline in a cohort of older adults in northern Manhattan.
Kulick ER, Elkind MSV, Boehme AK, Joyce NR, Schupf N, Kaufman JD, Mayeux R, Manly JJ, Wellenius GA. Kulick ER, et al. Among authors: schupf n. Environ Int. 2020 Mar;136:105440. doi: 10.1016/j.envint.2019.105440. Epub 2020 Jan 8. Environ Int. 2020. PMID: 31926436 Free PMC article.
BACKGROUND: There is mounting evidence that long-term exposure to air pollution is related to accelerated cognitive decline in aging populations. ...OBJECTIVES: We assessed whether the association between long-term exposure to ambient air pollution and cognitive dec …
BACKGROUND: There is mounting evidence that long-term exposure to air pollution is related to accelerated cognitive decline in aging …
Association of Subclinical Hearing Loss With Cognitive Performance.
Golub JS, Brickman AM, Ciarleglio AJ, Schupf N, Luchsinger JA. Golub JS, et al. Among authors: schupf n. JAMA Otolaryngol Head Neck Surg. 2020 Jan 1;146(1):57-67. doi: 10.1001/jamaoto.2019.3375. JAMA Otolaryngol Head Neck Surg. 2020. PMID: 31725853 Free PMC article.
For example, there was a 2.28-point (95% CI, 1.56-3.00) combined cohort DSST score decrease per 10-dB decrease among individuals with normal hearing vs a 0.97-point (95% CI, 0.20-1.75) decrease among those with HL, with a significant interaction term between continuous and …
For example, there was a 2.28-point (95% CI, 1.56-3.00) combined cohort DSST score decrease per 10-dB decrease among individuals with normal …
Long-Term Test-Retest Reliability of the UPSIT in Cognitively Intact Older Adults.
Devanand DP, Liu X, Cohen H, Budrow J, Schupf N, Manly J, Lee S. Devanand DP, et al. Among authors: schupf n. Chem Senses. 2019 Jul 17;44(6):365-369. doi: 10.1093/chemse/bjz025. Chem Senses. 2019. PMID: 31111142 Free PMC article.
The objective of this study was to determine the long-term test-retest reliability of the University of Pennsylvania Smell Identification Test (UPSIT), and its individual items, in cognitively intact older adults. ...Consistency of item responses ranged from 50% to 90% acr …
The objective of this study was to determine the long-term test-retest reliability of the University of Pennsylvania Smell Identifica …
An improved method for detecting telomere size differences in T-lymphocyte interphases from older people with Down syndrome with and without mild cognitive impairment.
Jenkins EC, Ye L, Marchi E, Krinsky-McHale SJ, Zigman WB, Schupf N, Silverman WP. Jenkins EC, et al. Among authors: schupf n. Biol Methods Protoc. 2017 May 4;2(1):bpx005. doi: 10.1093/biomethods/bpx005. eCollection 2017 Jan. Biol Methods Protoc. 2017. PMID: 32161788 Free PMC article.
Telomere size (quantified by fluorescence intensity and physical lengths) in short-term T-lymphocyte cultures from adults with Down syndrome (DS) with and without mild cognitive impairment (MCI-DS) or dementia was compared. ...
Telomere size (quantified by fluorescence intensity and physical lengths) in short-term T-lymphocyte cultures from adults with Down s …
Mild cognitive impairment identified in older individuals with Down syndrome by reduced telomere signal numbers and shorter telomeres measured in microns.
Jenkins EC, Ye L, Velinov M, Krinsky-McHale SJ, Zigman WB, Schupf N, Silverman WP. Jenkins EC, et al. Among authors: schupf n. Am J Med Genet B Neuropsychiatr Genet. 2012 Jul;159B(5):598-604. doi: 10.1002/ajmg.b.32066. Epub 2012 May 16. Am J Med Genet B Neuropsychiatr Genet. 2012. PMID: 22592955 Free PMC article.
Previously, we established that short-term T lymphocyte cultures from people with Down syndrome (DS) and dementia (Alzheimer's disease) had shorter telomeres than did those from age- and sex-matched people with DS only, quantified as significantly reduced numbers of signal …
Previously, we established that short-term T lymphocyte cultures from people with Down syndrome (DS) and dementia (Alzheimer's diseas …
Long-term blood pressure fluctuation and cerebrovascular disease in an elderly cohort.
Brickman AM, Reitz C, Luchsinger JA, Manly JJ, Schupf N, Muraskin J, DeCarli C, Brown TR, Mayeux R. Brickman AM, et al. Among authors: schupf n. Arch Neurol. 2010 May;67(5):564-9. doi: 10.1001/archneurol.2010.70. Arch Neurol. 2010. PMID: 20457955 Free PMC article.
Elevated blood pressure (BP) and fluctuation in BP may lead to cerebrovascular disease through ischemic changes and compromised cerebral autoregulation. OBJECTIVE: To determine the association of BP and long-term fluctuation in BP with cerebrovascular disease. DESIGN: A co …
Elevated blood pressure (BP) and fluctuation in BP may lead to cerebrovascular disease through ischemic changes and compromised cerebral aut …
11 results