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The utility of implantable loop recorders in patient management: an age- and indication-stratified study in the outpatient-implant era.
Sanghvi MM, Jones DM, Kalindjian J, Monkhouse C, Providencia R, Schilling RJ, Ahluwalia N, Earley MJ, Finlay M. Sanghvi MM, et al. Eur Heart J Qual Care Clin Outcomes. 2022 Oct 26;8(7):770-777. doi: 10.1093/ehjqcco/qcab071. Eur Heart J Qual Care Clin Outcomes. 2022. PMID: 34601557
AIM: Implantable loop recorders (ILRs) are now routinely implanted for long-term cardiac monitoring in the clinical setting. The aim of this study was to examine the real-world performance of these devices focusing on the management changes made in response to ILR-recorded …
AIM: Implantable loop recorders (ILRs) are now routinely implanted for long-term cardiac monitoring in the clinical setting. The aim …
KICK OUT PD: Feasibility and quality of life in the pilot karate intervention to change kinematic outcomes in Parkinson's Disease.
Fleisher JE, Sennott BJ, Myrick E, Niemet CJ, Lee M, Whitelock CM, Sanghvi M, Liu Y, Ouyang B, Hall DA, Comella CL, Chodosh J. Fleisher JE, et al. Among authors: sanghvi m. PLoS One. 2020 Sep 9;15(9):e0237777. doi: 10.1371/journal.pone.0237777. eCollection 2020. PLoS One. 2020. PMID: 32903267 Free PMC article. Clinical Trial.
Controlled and longitudinal investigation is warranted to confirm our pilot findings and explore the long-term effects and sustainability of karate in PD. TRIAL REGISTRATION: Clinicaltrials.gov: NCT03555695....
Controlled and longitudinal investigation is warranted to confirm our pilot findings and explore the long-term effects and sustainabi …
The impact of menopausal hormone therapy (MHT) on cardiac structure and function: Insights from the UK Biobank imaging enhancement study.
Sanghvi MM, Aung N, Cooper JA, Paiva JM, Lee AM, Zemrak F, Fung K, Thomson RJ, Lukaschuk E, Carapella V, Kim YJ, Harvey NC, Piechnik SK, Neubauer S, Petersen SE. Sanghvi MM, et al. PLoS One. 2018 Mar 8;13(3):e0194015. doi: 10.1371/journal.pone.0194015. eCollection 2018. PLoS One. 2018. PMID: 29518141 Free PMC article.
To explore whether MHT use on each of the cardiac outcomes differed by age, multivariable regression models were constructed with a cross-product of age and MHT fitted as an interaction term. RESULTS: Of 1604 post-menopausal women, 513 (32%) had used MHT 3 years. ...
To explore whether MHT use on each of the cardiac outcomes differed by age, multivariable regression models were constructed with a cross-pr …
Resveratrol supplementation confers neuroprotection in cortical brain tissue of nonhuman primates fed a high-fat/sucrose diet.
Bernier M, Wahl D, Ali A, Allard J, Faulkner S, Wnorowski A, Sanghvi M, Moaddel R, Alfaras I, Mattison JA, Tarantini S, Tucsek Z, Ungvari Z, Csiszar A, Pearson KJ, de Cabo R. Bernier M, et al. Among authors: sanghvi m. Aging (Albany NY). 2016 May;8(5):899-916. doi: 10.18632/aging.100942. Aging (Albany NY). 2016. PMID: 27070252 Free PMC article.
Previous studies have shown positive effects of long-term resveratrol (RSV) supplementation in preventing pancreatic beta cell dysfunction, arterial stiffening and metabolic decline induced by high-fat/high-sugar (HFS) diet in nonhuman primates. ...The decreased expression …
Previous studies have shown positive effects of long-term resveratrol (RSV) supplementation in preventing pancreatic beta cell dysfun …
Alcohol-induced one-carbon metabolism impairment promotes dysfunction of DNA base excision repair in adult brain.
Fowler AK, Hewetson A, Agrawal RG, Dagda M, Dagda R, Moaddel R, Balbo S, Sanghvi M, Chen Y, Hogue RJ, Bergeson SE, Henderson GI, Kruman II. Fowler AK, et al. Among authors: sanghvi m. J Biol Chem. 2012 Dec 21;287(52):43533-42. doi: 10.1074/jbc.M112.401497. Epub 2012 Nov 1. J Biol Chem. 2012. PMID: 23118224 Free PMC article.
We propose that one-carbon metabolism (OCM) impairment associated with long term chronic ethanol intake is a key factor in ethanol-induced neurotoxicity, because OCM provides cells with DNA precursors for DNA repair and methyl groups for DNA methylation, both critical for …
We propose that one-carbon metabolism (OCM) impairment associated with long term chronic ethanol intake is a key factor in ethanol-in …