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Comparison of clinical outcomes in hospitalized patients with COVID-19 or non-COVID-19 community-acquired pneumonia in a prospective observational cohort study.
Meyer HJ, Mödl L, Unruh O, Xiang W, Berger S, Müller-Plathe M, Rohde G, Pletz MW, Rupp J, Suttorp N, Witzenrath M, Zoller T, Mittermaier M, Steinbeis F; CAPNETZ study group. Meyer HJ, et al. Among authors: rupp j. Infection. 2024 May 18. doi: 10.1007/s15010-024-02292-z. Online ahead of print. Infection. 2024. PMID: 38761325
PURPOSE: Coronavirus disease 2019 (COVID-19) and non-COVID-19 community-acquired pneumonia (NC-CAP) often result in hospitalization with considerable risks of mortality, ICU treatment, and long-term morbidity. A comparative analysis of clinical outcomes in COVID-19 CAP (C- …
PURPOSE: Coronavirus disease 2019 (COVID-19) and non-COVID-19 community-acquired pneumonia (NC-CAP) often result in hospitalization with con …
Do asymptomatic STEC-long-term carriers need to be isolated or decolonized? New evidence from a community case study and concepts in favor of an individualized strategy.
Sayk F, Hauswaldt S, Knobloch JK, Rupp J, Nitschke M. Sayk F, et al. Among authors: rupp j. Front Public Health. 2024 Apr 17;12:1364664. doi: 10.3389/fpubh.2024.1364664. eCollection 2024. Front Public Health. 2024. PMID: 38699424 Free PMC article.
Asymptomatic long-term carriers of Shigatoxin producing Escherichia coli (STEC) are regarded as potential source of STEC-transmission. ...Moreover, placebo-controlled prospective interventions on efficacy and safety of, e.g., azithromycin for decolonization in asymptomatic …
Asymptomatic long-term carriers of Shigatoxin producing Escherichia coli (STEC) are regarded as potential source of STEC-transmission …
Increased Expression of Anaphylatoxin C5a-Receptor-1 in Neutrophils and Natural Killer Cells of Preterm Infants.
Boeckel H, Karsten CM, Göpel W, Herting E, Rupp J, Härtel C, Hartz A. Boeckel H, et al. Among authors: rupp j. Int J Mol Sci. 2023 Jun 19;24(12):10321. doi: 10.3390/ijms241210321. Int J Mol Sci. 2023. PMID: 37373467 Free PMC article.
Via flow cytometry, we analyzed the expression pattern of C5a receptors on immune cells isolated from peripheral blood of preterm infants (n = 32) compared to those of their mothers (n = 25). Term infants and healthy adults served as controls. Preterm infants had a higher …
Via flow cytometry, we analyzed the expression pattern of C5a receptors on immune cells isolated from peripheral blood of preterm infants (n …
Increasing numbers and complexity of Staphylococcus aureus bloodstream infection-14 years of prospective evaluation at a German tertiary care centre with multi-centre validation of findings.
Mathé P, Göpel S, Hornuss D, Tobys D, Käding N, Eisenbeis S, Kohlmorgen B, Trauth J, Gölz H, Walker SV, Mischnik A, Peter S, Hölzl F, Rohde AM, Behnke M, Fritzenwanker M, Häcker G, Steffens B, Vehreschild M, Kramme E, Falgenhauer J, Peyerl-Hoffmann G, Seifert H, Rupp J, Gastmeier P, Imirzalioglu C, Tacconelli E, Kern W, Rieg S; DZIF R-Net Study Group. Mathé P, et al. Among authors: rupp j. Clin Microbiol Infect. 2023 Sep;29(9):1197.e9-1197.e15. doi: 10.1016/j.cmi.2023.05.031. Epub 2023 Jun 3. Clin Microbiol Infect. 2023. PMID: 37277092
First-Day-of-Life Rectal Swabs Fail To Represent Meconial Microbiota Composition and Underestimate the Presence of Antibiotic Resistance Genes.
Graspeuntner S, Lupatsii M, Dashdorj L, Rody A, Rupp J, Bossung V, Härtel C. Graspeuntner S, et al. Among authors: rupp j. Microbiol Spectr. 2023 Jun 15;11(3):e0525422. doi: 10.1128/spectrum.05254-22. Epub 2023 Apr 25. Microbiol Spectr. 2023. PMID: 37097170 Free PMC article.
We have put together our knowledge on this critical aspect with careful consideration and identified the failure of rectal swabs to be a replacement for sampling of meconium in term-born newborns....
We have put together our knowledge on this critical aspect with careful consideration and identified the failure of rectal swabs to be a rep …
Delayed Microbial Maturation Durably Exacerbates Th17-driven Asthma in Mice.
Wilburn AN, McAlees JW, Haslam DB, Graspeuntner S, Schmudde I, Laumonnier Y, Rupp J, Chougnet CA, Deshmukh H, Zacharias WJ, König P, Lewkowich IP. Wilburn AN, et al. Among authors: rupp j. Am J Respir Cell Mol Biol. 2023 May;68(5):498-510. doi: 10.1165/rcmb.2022-0367OC. Am J Respir Cell Mol Biol. 2023. PMID: 36622830 Free PMC article.
We sought to understand how delaying microbial maturation drives worsened asthma outcomes later in life and its long-term durability. Drinking water was supplemented with antibiotics on Postnatal Days 10-20. To assess the immediate and long-term effects of delaying …
We sought to understand how delaying microbial maturation drives worsened asthma outcomes later in life and its long-term durability. …
Vancomycin-resistant Enterococcus faecium: admission prevalence, sequence types and risk factors-a cross-sectional study in seven German university hospitals from 2014 to 2018.
Rohde AM, Walker S, Behnke M, Eisenbeis S, Falgenhauer L, Falgenhauer JC, Häcker G, Hölzl F, Imirzalioglu C, Käding N, Kern WV, Kola A, Kramme E, Mischnik A, Peter S, Rieg S, Rupp J, Schneider C, Schwab F, Seifert H, Tacconelli E, Tobys D, Trauth J, Weber A, Xanthopoulou K, Zweigner J, Higgins PG, Gastmeier P; DZIF R-NET Study Group. Rohde AM, et al. Among authors: rupp j. Clin Microbiol Infect. 2023 Apr;29(4):515-522. doi: 10.1016/j.cmi.2022.11.025. Epub 2022 Dec 5. Clin Microbiol Infect. 2023. PMID: 36481293 Free article.
METHODS: From 2014 to 2018, patients were recruited within 72 hours of admission to seven participating German university hospitals, screened for VREfm and questioned for potential risk factors (prior multidrug-resistant organism detection, current/prior antibiotic consumption, p …
METHODS: From 2014 to 2018, patients were recruited within 72 hours of admission to seven participating German university hospitals, screene …
Modified Juvenile Spondyloarthritis Disease Activity Index in the Childhood Arthritis and Rheumatology Research Alliance (CARRA) Registry.
Srinivasalu H, Treemarcki EB, Rumsey DG, Weiss PF, Colbert RA; CARRA Spondyloarthritis Workgroup and the CARRA Registry Investigators. Srinivasalu H, et al. J Rheumatol. 2023 Apr;50(4):532-537. doi: 10.3899/jrheum.220509. Epub 2022 Nov 1. J Rheumatol. 2023. PMID: 36319008 Free PMC article.
All versions of JSpADA had excellent discriminative validity. CONCLUSION: We propose the term modified JSpADA for the modification of JSpADA with 6 elements (JSpADA6-no Schober, no CRP/ESR). ...
All versions of JSpADA had excellent discriminative validity. CONCLUSION: We propose the term modified JSpADA for the modification of …
Unmet needs in pneumonia research: a comprehensive approach by the CAPNETZ study group.
Pletz MW, Jensen AV, Bahrs C, Davenport C, Rupp J, Witzenrath M, Barten-Neiner G, Kolditz M, Dettmer S, Chalmers JD, Stolz D, Suttorp N, Aliberti S, Kuebler WM, Rohde G. Pletz MW, et al. Among authors: rupp j. Respir Res. 2022 Sep 10;23(1):239. doi: 10.1186/s12931-022-02117-3. Respir Res. 2022. PMID: 36088316 Free PMC article. Review.
RESULTS: Eleven topics for future CAP research were identified: detection of causative pathogens, next generation sequencing for antimicrobial treatment guidance, imaging diagnostics, biomarkers, risk stratification, antiviral and antibiotic treatment, adjunctive therapy, vaccine …
RESULTS: Eleven topics for future CAP research were identified: detection of causative pathogens, next generation sequencing for antimicrobi …
Protocol of the Luebeck longitudinal investigation of SARS-CoV-2 infection (ELISA) study - a prospective population-based cohort study.
Balck A, Föh B, Borsche M, Rahmöller J, Vollstedt EJ, Waldeck F, Käding N, Twesten C, Mischnik A, Gillessen-Kaesbach G, Ehlers M, Sina C, Taube S, Busch H, Rupp J, Katalinic A, Klein C. Balck A, et al. Among authors: rupp j. BMC Public Health. 2022 Jul 7;22(1):1305. doi: 10.1186/s12889-022-13666-z. BMC Public Health. 2022. PMID: 35799167 Free PMC article.
We will be able to monitor the pandemic continuously and discover potential sequelae of an infection long-term. Further examinations can be readily set up on an ad-hoc basis in the future. ...
We will be able to monitor the pandemic continuously and discover potential sequelae of an infection long-term. Further examinations …
40 results