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A defective viral genome strategy elicits broad protective immunity against respiratory viruses.
Xiao Y, Lidsky PV, Shirogane Y, Aviner R, Wu CT, Li W, Zheng W, Talbot D, Catching A, Doitsh G, Su W, Gekko CE, Nayak A, Ernst JD, Brodsky L, Brodsky E, Rousseau E, Capponi S, Bianco S, Nakamura R, Jackson PK, Frydman J, Andino R. Xiao Y, et al. Among authors: rousseau e. Cell. 2021 Dec 9;184(25):6037-6051.e14. doi: 10.1016/j.cell.2021.11.023. Epub 2021 Nov 18. Cell. 2021. PMID: 34852237 Free PMC article.
Thus, eTIP1 is a safe and effective broad-spectrum antiviral generating short- and long-term protection against SARS-CoV-2 and other respiratory infections in animal models....
Thus, eTIP1 is a safe and effective broad-spectrum antiviral generating short- and long-term protection against SARS-CoV-2 and other …
Activation of TRPV4 channels leads to a consistent tocolytic effect on human myometrial tissues.
Villegas D, Giard O, Brochu-Gaudreau K, Rousseau É. Villegas D, et al. Among authors: rousseau e. Eur J Obstet Gynecol Reprod Biol X. 2021 Mar 2;10:100124. doi: 10.1016/j.eurox.2021.100124. eCollection 2021 Apr. Eur J Obstet Gynecol Reprod Biol X. 2021. PMID: 33733088 Free PMC article.
STUDY DESIGN: Uterine biopsies were obtained from consenting women undergoing elective caesarean delivery at term without labor (N = 22). Isometric tension measurements were performed on uterine smooth muscle strips (n = 132). ...
STUDY DESIGN: Uterine biopsies were obtained from consenting women undergoing elective caesarean delivery at term without labor (N = …
Safety and immunogenicity of the live attenuated intranasal pertussis vaccine BPZE1: a phase 1b, double-blind, randomised, placebo-controlled dose-escalation study.
Jahnmatz M, Richert L, Al-Tawil N, Storsaeter J, Colin C, Bauduin C, Thalen M, Solovay K, Rubin K, Mielcarek N, Thorstensson R, Locht C; BPZE1 study team. Jahnmatz M, et al. Lancet Infect Dis. 2020 Nov;20(11):1290-1301. doi: 10.1016/S1473-3099(20)30274-7. Epub 2020 Jul 17. Lancet Infect Dis. 2020. PMID: 32687804 Clinical Trial.
BACKGROUND: Long-term protection and herd immunity induced by existing pertussis vaccines are imperfect, and a need therefore exists to develop new pertussis vaccines. ...
BACKGROUND: Long-term protection and herd immunity induced by existing pertussis vaccines are imperfect, and a need therefore exists …
The quantum-optics Hamiltonian in the Multipolar gauge.
Rousseau E, Felbacq D. Rousseau E, et al. Sci Rep. 2017 Sep 11;7(1):11115. doi: 10.1038/s41598-017-11076-5. Sci Rep. 2017. PMID: 28894205 Free PMC article.
We find that the gauge is not fixed in the Power-Zienau-Woolley hamiltonian. The interaction term is written in one gauge whereas the rest of the hamiltonian is written in another gauge. ...
We find that the gauge is not fixed in the Power-Zienau-Woolley hamiltonian. The interaction term is written in one gauge whereas the …
Phorbol 12,13-dibutyrate-induced protein kinase C activation triggers sustained contracture in human myometrium in vitro.
Massenavette L, Paul W, Corriveau S, Pasquier JC, Rousseau É. Massenavette L, et al. Among authors: rousseau e. Am J Obstet Gynecol. 2017 Sep;217(3):358.e1-358.e9. doi: 10.1016/j.ajog.2017.04.041. Epub 2017 May 4. Am J Obstet Gynecol. 2017. PMID: 28479286
STUDY DESIGN: Uterine biopsies were obtained from consenting women undergoing elective caesarian delivery at term without labor (N = 19). Isometric tension measurements were performed on uterine strips (n = 114). ...
STUDY DESIGN: Uterine biopsies were obtained from consenting women undergoing elective caesarian delivery at term without labor (N = …
Pro-Resolving Effects of Resolvin D2 in LTD4 and TNF-α Pre-Treated Human Bronchi.
Khaddaj-Mallat R, Sirois C, Sirois M, Rizcallah E, Marouan S, Morin C, Rousseau É. Khaddaj-Mallat R, et al. Among authors: rousseau e. PLoS One. 2016 Dec 9;11(12):e0167058. doi: 10.1371/journal.pone.0167058. eCollection 2016. PLoS One. 2016. PMID: 27935998 Free PMC article.
Our hypothesis is that resolution of inflammation may represent a long-term solution in preventing human bronchial dysfunctions. The aim of the present study was to assess the anti-inflammatory effects of RvD2, a member of the D-series resolving family, with concomitant ef …
Our hypothesis is that resolution of inflammation may represent a long-term solution in preventing human bronchial dysfunctions. The …
Resolvin E1 normalizes contractility, Ca2+ sensitivity and smooth muscle cell migration rate in TNF-α- and IL-6-pretreated human pulmonary arteries.
Hiram R, Rizcallah E, Marouan S, Sirois C, Sirois M, Morin C, Fortin S, Rousseau E. Hiram R, et al. Among authors: rousseau e. Am J Physiol Lung Cell Mol Physiol. 2015 Oct 15;309(8):L776-88. doi: 10.1152/ajplung.00177.2015. Epub 2015 Aug 28. Am J Physiol Lung Cell Mol Physiol. 2015. PMID: 26320154 Free article.
Our hypothesis is that artery-relaxing drugs are not the long-term solution, but rather the inhibition of tissue inflammation, which underlies human pulmonary artery (HPA) dysfunctions that lead to abnormal vasoconstriction. ...
Our hypothesis is that artery-relaxing drugs are not the long-term solution, but rather the inhibition of tissue inflammation, which …
Usefulness of Time-Point Serum Cortisol and ACTH Measurements for the Adjustment of Glucocorticoid Replacement in Adrenal Insufficiency.
Rousseau E, Joubert M, Trzepla G, Parienti JJ, Freret T, Vanthygem MC, Desailloud R, Lefebvre H, Coquerel A, Reznik Y; PHAD Study Group. Rousseau E, et al. PLoS One. 2015 Aug 28;10(8):e0135975. doi: 10.1371/journal.pone.0135975. eCollection 2015. PLoS One. 2015. PMID: 26317782 Free PMC article. Clinical Trial.
BACKGROUND: Adjustment of daily hydrocortisone dose on clinical criteria lacks sensitivity for fine tuning. Long term hydrocortisone (HC) over-replacement may lead to increased morbidity and mortality in patients with adrenal insufficiency (AI). ...
BACKGROUND: Adjustment of daily hydrocortisone dose on clinical criteria lacks sensitivity for fine tuning. Long term hydrocortisone …
Leukotriene receptor antagonist as a novel tocolytic in an in vitro model of human uterine contractility.
Corriveau S, Rousseau É, Blouin S, Pasquier JC. Corriveau S, et al. Among authors: rousseau e. Eur J Obstet Gynecol Reprod Biol. 2014 Jun;177:77-83. doi: 10.1016/j.ejogrb.2014.02.042. Epub 2014 Mar 12. Eur J Obstet Gynecol Reprod Biol. 2014. PMID: 24735655
STUDY DESIGN: Uterine biopsies were obtained from consenting women undergoing elective cesarean sections at term (n=20). Myometrial microsomal fractions were analyzed by immunoblotting to quantify relative cysteinyl leukotrienes receptor 1 (CysLTR1) levels. ...
STUDY DESIGN: Uterine biopsies were obtained from consenting women undergoing elective cesarean sections at term (n=20). Myometrial m …
16 results