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Human airway organoid engineering as a step toward lung regeneration and disease modeling.
Biomaterials. 2017 Jan;113:118-132. doi: 10.1016/j.biomaterials.2016.10.046. Epub 2016 Oct 28.
Biomaterials. 2017.
PMID: 27815996
Free PMC article.
We demonstrate that randomly-seeded mixed cell populations undergo rapid condensation and self-organization into discrete epithelial and endothelial structures that are mechanically robust and stable during long term culture. After condensation airway organoids generate in …
We demonstrate that randomly-seeded mixed cell populations undergo rapid condensation and self-organization into discrete epithelial and end …
Coming to terms with tissue engineering and regenerative medicine in the lung.
Prakash YS, Tschumperlin DJ, Stenmark KR.
Prakash YS, et al.
Am J Physiol Lung Cell Mol Physiol. 2015 Oct 1;309(7):L625-38. doi: 10.1152/ajplung.00204.2015. Epub 2015 Aug 7.
Am J Physiol Lung Cell Mol Physiol. 2015.
PMID: 26254424
Free PMC article.
Review.
However, limited donor lung availability, graft rejection, and long-term problems after transplantation are major hurdles to lung transplantation being a panacea. ...
However, limited donor lung availability, graft rejection, and long-term problems after transplantation are major hurdles to lung tra …
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