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Programming Directional Deep Brain Stimulation in Parkinson's Disease: A Randomized Prospective Trial Comparing Early versus Delayed Stimulation Steering.
Maciel R, Soh D, Munhoz RP, Poon YY, Kalia SK, Hodaie M, Lozano AM, Fasano A. Maciel R, et al. Among authors: poon yy. Stereotact Funct Neurosurg. 2021;99(6):484-490. doi: 10.1159/000517054. Epub 2021 Jun 29. Stereotact Funct Neurosurg. 2021. PMID: 34350897 Free article. Clinical Trial.
CONCLUSION: Programming with early or delayed steered stimulation is equally effective in the short term. However, delayed steering is less time consuming and is not always needed....
CONCLUSION: Programming with early or delayed steered stimulation is equally effective in the short term. However, delayed steering i …
Chronic Obstructive Pulmonary Disease as a Phenotype of Bronchiectasis for Long-Term Clinical Presentation and Treatment.
Hsu CY, Poon YY, Chen YW, Hsieh MH, Lin HC, Fang WF. Hsu CY, et al. Among authors: poon yy. Medicina (Kaunas). 2021 Jun 5;57(6):579. doi: 10.3390/medicina57060579. Medicina (Kaunas). 2021. PMID: 34198847 Free PMC article.
Conclusion: COPD aggravated bronchiectasis extension, which was correlated with chronic Pseudomonas aeruginosa colonisation. Moreover, COPD would affect the medium-term (in 3-5 years) bronchiectasis treatment. Therefore, the COPD phenotype of bronchiectasis could be a clin …
Conclusion: COPD aggravated bronchiectasis extension, which was correlated with chronic Pseudomonas aeruginosa colonisation. Moreover, COPD …
Levodopa Versus Dopamine Agonist after Subthalamic Stimulation in Parkinson's Disease.
Picillo M, Phokaewvarangkul O, Poon YY, McIntyre CC, Beylergil SB, Munhoz RP, Kalia SK, Hodaie M, Lozano AM, Fasano A. Picillo M, et al. Among authors: poon yy. Mov Disord. 2021 Mar;36(3):672-680. doi: 10.1002/mds.28382. Epub 2020 Nov 9. Mov Disord. 2021. PMID: 33165964 Free PMC article. Clinical Trial.
All patients were reevaluated in short- (3 months), mid- (6 months), and long-term (2.5 years) follow-up after surgery. The primary outcome measure was the change in the Non-Motor Symptoms Scale (NMSS) 3 months after surgery. ...RESULTS: Randomization did not significantly …
All patients were reevaluated in short- (3 months), mid- (6 months), and long-term (2.5 years) follow-up after surgery. The primary o …
Predictors of deep brain stimulation outcome in tremor patients.
Sandoe C, Krishna V, Basha D, Sammartino F, Tatsch J, Picillo M, di Biase L, Poon YY, Hamani C, Reddy D, Munhoz RP, Lozano AM, Hutchison WD, Fasano A. Sandoe C, et al. Among authors: poon yy. Brain Stimul. 2018 May-Jun;11(3):592-599. doi: 10.1016/j.brs.2017.12.014. Epub 2018 Jan 2. Brain Stimul. 2018. PMID: 29330020
RESULTS: A total of 52 patients were included in the final analysis: 31 with essential tremor, 15 with cerebellar tremor of different etiologies, and 6 with Parkinson's disease. Long-term success (mean follow-up duration 34.7 months, range 1.7-121.1 months) was reported in …
RESULTS: A total of 52 patients were included in the final analysis: 31 with essential tremor, 15 with cerebellar tremor of different etiolo …
Long-term double-blinded unilateral pedunculopontine area stimulation in Parkinson's disease.
Mestre TA, Sidiropoulos C, Hamani C, Poon YY, Lozano AM, Lang AE, Moro E. Mestre TA, et al. Among authors: poon yy. Mov Disord. 2016 Oct;31(10):1570-1574. doi: 10.1002/mds.26710. Mov Disord. 2016. PMID: 27392513 Clinical Trial.
OBJECTIVES: The objective of this study was to determine the long-term efficacy and safety of unilateral pedunculopontine area stimulation for refractory gait and balance impairment in Parkinson's disease. ...
OBJECTIVES: The objective of this study was to determine the long-term efficacy and safety of unilateral pedunculopontine area stimul …
Short- and long-term outcome of chronic pallidal neurostimulation in monogenic isolated dystonia.
Brüggemann N, Kühn A, Schneider SA, Kamm C, Wolters A, Krause P, Moro E, Steigerwald F, Wittstock M, Tronnier V, Lozano AM, Hamani C, Poon YY, Zittel S, Wächter T, Deuschl G, Krüger R, Kupsch A, Münchau A, Lohmann K, Volkmann J, Klein C. Brüggemann N, et al. Among authors: poon yy. Neurology. 2015 Mar 3;84(9):895-903. doi: 10.1212/WNL.0000000000001312. Epub 2015 Feb 4. Neurology. 2015. PMID: 25653290 Free PMC article.
Regardless of the genotype, patients with a shorter duration from onset of dystonia to surgery had better control of dystonia postoperatively. CONCLUSIONS: Long-term GPi-DBS is effective in patients with DYT6, DYT1, and non-DYT dystonia. ...CLASSIFICATION OF EVIDENCE: This …
Regardless of the genotype, patients with a shorter duration from onset of dystonia to surgery had better control of dystonia postoperativel …
Low-frequency subthalamic nucleus deep brain stimulation for axial symptoms in advanced Parkinson's disease.
Sidiropoulos C, Walsh R, Meaney C, Poon YY, Fallis M, Moro E. Sidiropoulos C, et al. Among authors: poon yy. J Neurol. 2013 Sep;260(9):2306-11. doi: 10.1007/s00415-013-6983-2. Epub 2013 Jun 9. J Neurol. 2013. PMID: 23749331 Clinical Trial.
However, it is typically less effective in improving axial symptomatology, especially in the long term. We have studied the effects of low-frequency stimulation (LFS) (80 Hz) for improving speech, gait and balance dysfunction in the largest patient population to date. ...
However, it is typically less effective in improving axial symptomatology, especially in the long term. We have studied the effects o …
Bilateral pallidal stimulation in cervical dystonia: blinded evidence of benefit beyond 5 years.
Walsh RA, Sidiropoulos C, Lozano AM, Hodaie M, Poon YY, Fallis M, Moro E. Walsh RA, et al. Among authors: poon yy. Brain. 2013 Mar;136(Pt 3):761-9. doi: 10.1093/brain/awt009. Epub 2013 Feb 18. Brain. 2013. PMID: 23423670
Although cervical dystonia is the most common idiopathic focal dystonia, evidence for long-term responsiveness to pallidal stimulation is limited. The primary objective of this study was to prospectively collect outcome data from baseline to last clinical follow-up on pati …
Although cervical dystonia is the most common idiopathic focal dystonia, evidence for long-term responsiveness to pallidal stimulatio …
Long-term effect of unilateral pallidotomy on levodopa-induced dyskinesia.
Kleiner-Fisman G, Lozano A, Moro E, Poon YY, Lang AE. Kleiner-Fisman G, et al. Among authors: poon yy. Mov Disord. 2010 Jul 30;25(10):1496-8. doi: 10.1002/mds.23155. Mov Disord. 2010. PMID: 20568091
Unilateral pallidotomy has been effectively used to treat parkinsonism and reduce levodopa induced dyskinesia (LID). We sought to determine the long-term effects of pallidotomy on LID in 10 patients who had initial benefit from pallidotomy but went on to require DBS surger …
Unilateral pallidotomy has been effectively used to treat parkinsonism and reduce levodopa induced dyskinesia (LID). We sought to determine …
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