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Page 1
Long-term (180-Day) Outcomes in Critically Ill Patients With COVID-19 in the REMAP-CAP Randomized Clinical Trial.
Writing Committee for the REMAP-CAP Investigators; Higgins AM, Berry LR, Lorenzi E, Murthy S, McQuilten Z, Mouncey PR, Al-Beidh F, Annane D, Arabi YM, Beane A, van Bentum-Puijk W, Bhimani Z, Bonten MJM, Bradbury CA, Brunkhorst FM, Burrell A, Buzgau A, Buxton M, Charles WN, Cove M, Detry MA, Estcourt LJ, Fagbodun EO, Fitzgerald M, Girard TD, Goligher EC, Goossens H, Haniffa R, Hills T, Horvat CM, Huang DT, Ichihara N, Lamontagne F, Marshall JC, McAuley DF, McGlothlin A, McGuinness SP, McVerry BJ, Neal MD, Nichol AD, Parke RL, Parker JC, Parry-Billings K, Peters SEC, Reyes LF, Rowan KM, Saito H, Santos MS, Saunders CT, Serpa-Neto A, Seymour CW, Shankar-Hari M, Stronach LM, Turgeon AF, Turner AM, van de Veerdonk FL, Zarychanski R, Green C, Lewis RJ, Angus DC, McArthur CJ, Berry S, Derde LPG, Gordon AC, Webb SA, Lawler PR. Writing Committee for the REMAP-CAP Investigators, et al. JAMA. 2023 Jan 3;329(1):39-51. doi: 10.1001/jama.2022.23257. JAMA. 2023. PMID: 36525245 Free PMC article.
IMPORTANCE: The longer-term effects of therapies for the treatment of critically ill patients with COVID-19 are unknown. OBJECTIVE: To determine the effect of multiple interventions for critically ill adults with COVID-19 on longer-term outcomes. DESIGN, SETTING, AN …
IMPORTANCE: The longer-term effects of therapies for the treatment of critically ill patients with COVID-19 are unknown. OBJECTIVE: T …
S. aureus endocarditis: Clinical aspects and experimental approaches.
Hoerr V, Franz M, Pletz MW, Diab M, Niemann S, Faber C, Doenst T, Schulze PC, Deinhardt-Emmer S, Löffler B. Hoerr V, et al. Among authors: pletz mw. Int J Med Microbiol. 2018 Aug;308(6):640-652. doi: 10.1016/j.ijmm.2018.02.004. Epub 2018 Feb 21. Int J Med Microbiol. 2018. PMID: 29526448 Review.
Rising patient age, increasing drug resistance, intensive treatment conditions such as renal hemodialysis, immunosuppression and long term indwelling central venous catheters but also the application of modern cardiac device implants and valve prosthesis have led to emergi …
Rising patient age, increasing drug resistance, intensive treatment conditions such as renal hemodialysis, immunosuppression and long ter …
Unmet needs in pneumonia research: a comprehensive approach by the CAPNETZ study group.
Pletz MW, Jensen AV, Bahrs C, Davenport C, Rupp J, Witzenrath M, Barten-Neiner G, Kolditz M, Dettmer S, Chalmers JD, Stolz D, Suttorp N, Aliberti S, Kuebler WM, Rohde G. Pletz MW, et al. Respir Res. 2022 Sep 10;23(1):239. doi: 10.1186/s12931-022-02117-3. Respir Res. 2022. PMID: 36088316 Free PMC article. Review.
RESULTS: Eleven topics for future CAP research were identified: detection of causative pathogens, next generation sequencing for antimicrobial treatment guidance, imaging diagnostics, biomarkers, risk stratification, antiviral and antibiotic treatment, adjunctive therapy, vaccine …
RESULTS: Eleven topics for future CAP research were identified: detection of causative pathogens, next generation sequencing for antimicrobi …
Long COVID: a narrative review of the clinical aftermaths of COVID-19 with a focus on the putative pathophysiology and aspects of physical activity.
Haunhorst S, Bloch W, Wagner H, Ellert C, Krüger K, Vilser DC, Finke K, Reuken P, Pletz MW, Stallmach A, Puta C. Haunhorst S, et al. Among authors: pletz mw. Oxf Open Immunol. 2022 Sep 16;3(1):iqac006. doi: 10.1093/oxfimm/iqac006. eCollection 2022. Oxf Open Immunol. 2022. PMID: 36846561 Free PMC article. Review.
The post-acute sequelae of COVID-19 (PASC), also referred to as long COVID, describe the persistence of symptoms and/or long-term complications beyond 4 weeks from the onset of the acute symptoms and are estimated to affect at least 20% of the individuals infected with SAR …
The post-acute sequelae of COVID-19 (PASC), also referred to as long COVID, describe the persistence of symptoms and/or long-term com …
[Biomarkers in community acquired pneumonia - what did we learn from the CAPNETZ study?].
Krüger S, Pletz MW, Rohde G. Krüger S, et al. Among authors: pletz mw. Pneumologie. 2011 Feb;65(2):110-3. doi: 10.1055/s-0030-1255935. Epub 2010 Nov 29. Pneumologie. 2011. PMID: 21117019 Free article. Review. German.
New cardiovascular biomarkers are good predictors for short- and long-term mortality in CAP, superior to the inflammatory markers procalcitonin, CRP and leukocytes and at least comparable to the clinical CRB-65 score. ...New cardiovascular biomarkers are suitable for the e …
New cardiovascular biomarkers are good predictors for short- and long-term mortality in CAP, superior to the inflammatory markers pro …
High prevalence of long-term olfactory dysfunction confirmed by olfactory testing after a community COVID-19 outbreak.
Gudziol H, Kirschstein T, Pletz MW, Weis S, Guntinas-Lichius O, Bitter T; CoNAN study group. Gudziol H, et al. Among authors: pletz mw. HNO. 2022 Mar;70(3):224-231. doi: 10.1007/s00106-021-01129-7. Epub 2021 Dec 23. HNO. 2022. PMID: 34940903 Free PMC article.
PURPOSE: The prevalence of long-term olfactory and gustatory dysfunction in participants suffering from sudden chemosensory loss due to coronavirus disease 2019 (COVID-19) is unknown. ...Normogeusia and hypogeusia were objectified in 39 and four participants, respectively. …
PURPOSE: The prevalence of long-term olfactory and gustatory dysfunction in participants suffering from sudden chemosensory loss due …
Complicated Long Term Vaccine Induced Thrombotic Immune Thrombocytopenia-A Case Report.
Günther A, Brämer D, Pletz MW, Kamradt T, Baumgart S, Mayer TE, Baier M, Autsch A, Mawrin C, Schönborn L, Greinacher A, Thiele T. Günther A, et al. Among authors: pletz mw. Vaccines (Basel). 2021 Nov 17;9(11):1344. doi: 10.3390/vaccines9111344. Vaccines (Basel). 2021. PMID: 34835275 Free PMC article.
Today it is unclear, how long symptomatic VITT can persist. Here, we report the complicated long-term course of a VITT patient with extremely high titers of pathogenic anti-platelet factor 4 (PF4)-IgG antibodies. ...Plasma exchange, immunoadsorption, and /or immunosuppress …
Today it is unclear, how long symptomatic VITT can persist. Here, we report the complicated long-term course of a VITT patient with e …
Linezolid - the first oxazolidinone in the treatment of nosocomial MRSA pneumonia.
Burkhardt O, Pletz MW, Mertgen CP, Welte T. Burkhardt O, et al. Among authors: pletz mw. Recent Pat Antiinfect Drug Discov. 2007 Jun;2(2):123-30. doi: 10.2174/157489107780832659. Recent Pat Antiinfect Drug Discov. 2007. PMID: 18221168 Review.
Reduced susceptibility to linezolid is caused by point mutations in the 23S ribosomal RNA genes, which may be selected for by long-term therapy. The future development of linezolid resistance is hard to predict since the drug has been in use only for a limited period of ti …
Reduced susceptibility to linezolid is caused by point mutations in the 23S ribosomal RNA genes, which may be selected for by long-term …
Persistent humoral and CD4(+) T(H) cell immunity after mild SARS-COV-2 infection-The CoNAN long-term study.
Schnizer C, Andreas N, Vivas W, Kamradt T, Baier M, Kiehntopf M, Glöckner S, Scherag A, Löffler B, Kolanos S, Guerra J, Pletz MW, Weis S. Schnizer C, et al. Among authors: pletz mw. Front Immunol. 2023 Jan 13;13:1095129. doi: 10.3389/fimmu.2022.1095129. eCollection 2022. Front Immunol. 2023. PMID: 36713390 Free PMC article.
Understanding persistent cellular and humoral immune responses to SARS-CoV-2 will be of major importance to terminate the ongoing pandemic. Here, we assessed long-term immunity in individuals with mild COVID-19 up to 1 year after a localized SARS-CoV-2 outbreak. ...
Understanding persistent cellular and humoral immune responses to SARS-CoV-2 will be of major importance to terminate the ongoing pandemic. …
Group Vaccination Five Days before a COVID-19 Outbreak in a Long-Term Care Facility.
Pletz MW, Trommer S, Kolanos S, Rose N, Kinne V, Spott R, Baier M, Lange I. Pletz MW, et al. Vaccines (Basel). 2021 Dec 8;9(12):1450. doi: 10.3390/vaccines9121450. Vaccines (Basel). 2021. PMID: 34960196 Free PMC article.
Rapid vaccination may be of benefit in long-term care facilities (LTCF) that are affected by an ongoing COVID-19 outbreak. ...
Rapid vaccination may be of benefit in long-term care facilities (LTCF) that are affected by an ongoing COVID-19 outbreak. ...
39 results