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P2Y6 Receptor Activation Aggravates NLRP3-dependent Microglial Pyroptosis via Downregulation of the PI3K/AKT Pathway in a Mouse Model of Intracerebral Hemorrhage.
Li Y, Tu H, Zhang S, Ding Z, Wu G, Piao J, Lv D, Hu L, Li F, Wang Q. Li Y, et al. Among authors: piao j. Mol Neurobiol. 2023 Dec 11. doi: 10.1007/s12035-023-03834-6. Online ahead of print. Mol Neurobiol. 2023. PMID: 38079109
P2Y6R was only expressed on microglia. MRS2578, a specific inhibitor of P2Y6R, attenuated short-term neurobehavioral deficits, brain edema and hematoma volume while improving both microglial pyroptosis and WMI. ...
P2Y6R was only expressed on microglia. MRS2578, a specific inhibitor of P2Y6R, attenuated short-term neurobehavioral deficits, brain …
A review on surgical treatment options in gliomas.
Yang Z, Zhao C, Zong S, Piao J, Zhao Y, Chen X. Yang Z, et al. Among authors: piao j. Front Oncol. 2023 Mar 16;13:1088484. doi: 10.3389/fonc.2023.1088484. eCollection 2023. Front Oncol. 2023. PMID: 37007123 Free PMC article. Review.
In this study, based on the introduction of gliomas, we review the novel surgical techniques and technologies in support of the extent of resection to achieve long-term disease control and summarize the findings on how to keep the balance between cytoreduction and neurolog …
In this study, based on the introduction of gliomas, we review the novel surgical techniques and technologies in support of the extent of re …
Basic Amino Acids Modulated Neutral-pH PEDOT:PSS for Stable Blue Perovskite Light-Emitting Diodes.
Liu L, Dong R, Ge H, Piao J, Wang Y, Li S, Shen W, Cao K, Chen S. Liu L, et al. Among authors: piao j. ACS Appl Mater Interfaces. 2022 Jun 22;14(24):28133-28144. doi: 10.1021/acsami.2c06727. Epub 2022 Jun 8. ACS Appl Mater Interfaces. 2022. PMID: 35674387
As the most popular hole transport layer, poly(3,4-ethylenedioxythiophene):polystyrenesulfonate (PEDOT:PSS) bears the acidic and hygroscopic drawbacks, which deteriorates the device efficiency and long-term stability of blue PeLEDs. In this work, the basic amino acids with …
As the most popular hole transport layer, poly(3,4-ethylenedioxythiophene):polystyrenesulfonate (PEDOT:PSS) bears the acidic and hygroscopic …
[Outcome indicators in randomized controlled trials on traditional Chinese medicine intervention for tension-type headache in recent five years].
Gong X, Wei JJ, Fu GJ, Fan XM, Piao JZ, Chen WJ, Yan Y, Zhang YL, Guo CL, Liao X. Gong X, et al. Among authors: piao jz. Zhongguo Zhong Yao Za Zhi. 2021 Sep;46(18):4591-4600. doi: 10.19540/j.cnki.cjcmm.20210722.502. Zhongguo Zhong Yao Za Zhi. 2021. PMID: 34581067 Chinese.
The outcome indicators of RCTs included in this study were classified into seven domains: TCM syndrome, symptom and sign, physical and chemical detection, quality of life, long-term prognosis, economic evaluation, and safety event. The findings demonstrated that headache c …
The outcome indicators of RCTs included in this study were classified into seven domains: TCM syndrome, symptom and sign, physical and chemi …
Effects of Real-Ambient PM2.5 Exposure on Lung Damage Modulated by Nrf2-/.
Ding H, Jiang M, Li D, Zhao Y, Yu D, Zhang R, Chen W, Pi J, Chen R, Cui L, Zheng Y, Piao J. Ding H, et al. Among authors: piao j. Front Pharmacol. 2021 Apr 23;12:662664. doi: 10.3389/fphar.2021.662664. eCollection 2021. Front Pharmacol. 2021. PMID: 33967806 Free PMC article.
Previous studies have shown that long-term exposure to fine particulate matter (PM(2.5)) increases the morbidity and mortality of pulmonary diseases such as asthma, chronic obstructive pulmonary disease and pulmonary emphysema. ...
Previous studies have shown that long-term exposure to fine particulate matter (PM(2.5)) increases the morbidity and mortality of pul …
Fabrication and application of a novel electrochemical biosensor based on a mesoporous carbon sphere@UiO-66-NH2/Lac complex enzyme for tetracycline detection.
Zhong X, Wang F, Piao J, Chen Y. Zhong X, et al. Among authors: piao j. Analyst. 2021 May 4;146(9):2825-2833. doi: 10.1039/d0an02430a. Analyst. 2021. PMID: 33949365
The biosensor based on this complex enzyme exhibits a relatively low detection limit of 8.94 10-7 mol L-1 and a detection range of 1.0 10-6-6.0 10-5 mol L-1 for tetracycline detection. Furthermore, the developed biosensor possesses good long-term stability, selectivity and …
The biosensor based on this complex enzyme exhibits a relatively low detection limit of 8.94 10-7 mol L-1 and a detection range of 1.0 10-6- …
Preclinical Efficacy and Safety of a Human Embryonic Stem Cell-Derived Midbrain Dopamine Progenitor Product, MSK-DA01.
Piao J, Zabierowski S, Dubose BN, Hill EJ, Navare M, Claros N, Rosen S, Ramnarine K, Horn C, Fredrickson C, Wong K, Safford B, Kriks S, El Maarouf A, Rutishauser U, Henchcliffe C, Wang Y, Riviere I, Mann S, Bermudez V, Irion S, Studer L, Tomishima M, Tabar V. Piao J, et al. Cell Stem Cell. 2021 Feb 4;28(2):217-229.e7. doi: 10.1016/j.stem.2021.01.004. Cell Stem Cell. 2021. PMID: 33545080 Free PMC article.
We have generated midbrain dopamine neurons from human embryonic stem cells and manufactured large-scale cryopreserved dopamine progenitors for clinical use. After optimizing cell survival and phenotypes in short-term studies, the cell product, MSK-DA01, was subjected to a …
We have generated midbrain dopamine neurons from human embryonic stem cells and manufactured large-scale cryopreserved dopamine progenitors …
Trial Design Challenges and Approaches for Precision Oncology in Rare Tumors: Experiences of the Children's Oncology Group.
Renfro LA, Ji L, Piao J, Onar-Thomas A, Kairalla JA, Alonzo TA. Renfro LA, et al. Among authors: piao j. JCO Precis Oncol. 2019 Oct 24;3:PO.19.00060. doi: 10.1200/PO.19.00060. eCollection 2019. JCO Precis Oncol. 2019. PMID: 32923863 Free PMC article. Review.
Furthermore, even patients cured of pediatric cancer often experience severe adverse effects of treatment and other long-term health implications, such as cardiotoxicity or loss of fertility. ...
Furthermore, even patients cured of pediatric cancer often experience severe adverse effects of treatment and other long-term health …
Long-term clinically relevant rodent model of methotrexate-induced cognitive impairment.
Berlin C, Lange K, Lekaye HC, Hopland K, Phillips S, Piao J, Tabar V. Berlin C, et al. Among authors: piao j. Neuro Oncol. 2020 Aug 17;22(8):1126-1137. doi: 10.1093/neuonc/noaa086. Neuro Oncol. 2020. PMID: 32242229 Free PMC article.
METHODS: Here, we use a clinically relevant regimen of several cycles of methotrexate and leucovorin rescue to develop a model of chemotherapy-induced cognitive impairment, and investigate the in vivo long-term (16 mo) impact of high-dose systemic methotrexate on white mat …
METHODS: Here, we use a clinically relevant regimen of several cycles of methotrexate and leucovorin rescue to develop a model of chemothera …
Substance P accelerates wound repair by promoting neovascularization and preventing inflammation in an ischemia mouse model.
Kim S, Piao J, Hwang DY, Park JS, Son Y, Hong HS. Kim S, et al. Among authors: piao j. Life Sci. 2019 May 15;225:98-106. doi: 10.1016/j.lfs.2019.04.015. Epub 2019 Apr 5. Life Sci. 2019. PMID: 30959026
AIMS: Arterial insufficiency ulcers are frequent complications of peripheral artery disease and infection or long-term neglect of the ulcer can eventually lead to amputation of the affected body part. ...
AIMS: Arterial insufficiency ulcers are frequent complications of peripheral artery disease and infection or long-term neglect of the …
18 results