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Derivation and validation of a clinical decision rule to risk-stratify COVID-19 patients discharged from the emergency department: The CCEDRRN COVID discharge score.
Brooks SC, Rosychuk RJ, Perry JJ, Morrison LJ, Wiemer H, Fok P, Rowe BH, Daoust R, Vatanpour S, Turner J, Landes M, Ohle R, Hayward J, Scheuermeyer F, Welsford M, Hohl C; Canadian COVID‐19 Rapid Response Network (CCEDRRN) for the Network of Canadian Emergency Researchers (NCER) and the Canadian Critical Care Trials Group (CCCTG). Brooks SC, et al. Among authors: perry jj. J Am Coll Emerg Physicians Open. 2022 Dec 22;3(6):e12868. doi: 10.1002/emp2.12868. eCollection 2022 Dec. J Am Coll Emerg Physicians Open. 2022. PMID: 36579029 Free PMC article.
We used logistic regression to develop the score in a derivation cohort and examined its performance in predicting short-term adverse outcomes in a validation cohort. RESULTS: Of 15,305 eligible patient visits, 535 (3.6%) experienced the outcome. ...CONCLUSION: The CCEDRRN …
We used logistic regression to develop the score in a derivation cohort and examined its performance in predicting short-term adverse …
Side-Population Trophoblasts Exhibit the Differentiation Potential of a Trophoblast Stem Cell Population, Persist to Term, and are Reduced in Fetal Growth Restriction.
Gamage TK, Perry JJ, Fan V, Groom K, Chamley LW, James JL. Gamage TK, et al. Among authors: perry jj. Stem Cell Rev Rep. 2020 Aug;16(4):764-775. doi: 10.1007/s12015-020-09991-8. Stem Cell Rev Rep. 2020. PMID: 32548656
Using the same technique, side-population trophoblasts could be isolated from term placentae for the first time, demonstrating that while they were present at consistent levels throughout gestation (~3.5%), side-population trophoblasts were significantly depleted in growth …
Using the same technique, side-population trophoblasts could be isolated from term placentae for the first time, demonstrating that w …
Frailty and associated outcomes and resource utilization following in-hospital cardiac arrest.
Fernando SM, McIsaac DI, Rochwerg B, Cook DJ, Bagshaw SM, Muscedere J, Munshi L, Nolan JP, Perry JJ, Downar J, Dave C, Reardon PM, Tanuseputro P, Kyeremanteng K. Fernando SM, et al. Among authors: perry jj. Resuscitation. 2020 Jan 1;146:138-144. doi: 10.1016/j.resuscitation.2019.11.011. Epub 2019 Nov 27. Resuscitation. 2020. PMID: 31785373
Secondary outcomes include return of spontaneous circulation (ROSC), discharge to long-term care, and hospital costs. We used multivariable logistic regression to adjust for known confounders. ...CONCLUSIONS: Frail individuals who experience an IHCA are more likely to die …
Secondary outcomes include return of spontaneous circulation (ROSC), discharge to long-term care, and hospital costs. We used multiva …
Frailty and Associated Outcomes and Resource Utilization Among Older ICU Patients With Suspected Infection.
Fernando SM, McIsaac DI, Perry JJ, Rochwerg B, Bagshaw SM, Thavorn K, Seely AJE, Forster AJ, Fiest KM, Dave C, Tran A, Reardon PM, Tanuseputro P, Kyeremanteng K. Fernando SM, et al. Among authors: perry jj. Crit Care Med. 2019 Aug;47(8):e669-e676. doi: 10.1097/CCM.0000000000003831. Crit Care Med. 2019. PMID: 31135504
Frailty was also associated with higher likelihood of discharge to long-term care (adjusted odds ratio, 2.06 [95% CI, 1.50-2.64]) and higher likelihood of readmission within 30 days (adjusted odds ratio, 1.83 [95% CI, 1.38-2.34]). ...CONCLUSIONS: The presence of frailty am …
Frailty was also associated with higher likelihood of discharge to long-term care (adjusted odds ratio, 2.06 [95% CI, 1.50-2.64]) and …
Clinical validation of a risk scale for serious outcomes among patients with chronic obstructive pulmonary disease managed in the emergency department.
Stiell IG, Perry JJ, Clement CM, Brison RJ, Rowe BH, Aaron SD, McRae AD, Borgundvaag B, Calder LA, Forster AJ, Brinkhurst J, Wells GA. Stiell IG, et al. Among authors: perry jj. CMAJ. 2018 Dec 3;190(48):E1406-E1413. doi: 10.1503/cmaj.180232. CMAJ. 2018. PMID: 30510045 Free PMC article.
RESULTS: We enrolled 1415 patients with a mean age of 70.6 (SD 10.6) years and 50.2% were female. Short-term serious outcomes occurred in 135 (9.5%) cases. Incidence of short-term serious outcomes ranged from 4.6% for a total score of 0 to 100% for a score of 10. Co …
RESULTS: We enrolled 1415 patients with a mean age of 70.6 (SD 10.6) years and 50.2% were female. Short-term serious outcomes occurre …
Prognostic Accuracy of the HEART Score for Prediction of Major Adverse Cardiac Events in Patients Presenting With Chest Pain: A Systematic Review and Meta-analysis.
Fernando SM, Tran A, Cheng W, Rochwerg B, Taljaard M, Thiruganasambandamoorthy V, Kyeremanteng K, Perry JJ. Fernando SM, et al. Among authors: perry jj. Acad Emerg Med. 2019 Feb;26(2):140-151. doi: 10.1111/acem.13649. Epub 2018 Nov 29. Acad Emerg Med. 2019. PMID: 30375097 Free article.
METHODS: We searched MEDLINE, PubMed, EMBASE, Scopus, Web of Science, and the Cochrane Database of Systematic Reviews from inception through May 2018 and included studies using the HEART score for the prediction of short-term MACE in adult patients presenting to the ED wit …
METHODS: We searched MEDLINE, PubMed, EMBASE, Scopus, Web of Science, and the Cochrane Database of Systematic Reviews from inception through …
Sepsis-3 Septic Shock Criteria and Associated Mortality Among Infected Hospitalized Patients Assessed by a Rapid Response Team.
Fernando SM, Reardon PM, Rochwerg B, Shapiro NI, Yealy DM, Seely AJE, Perry JJ, Barnaby DP, Murphy K, Tanuseputro P, Kyeremanteng K. Fernando SM, et al. Among authors: perry jj. Chest. 2018 Aug;154(2):309-316. doi: 10.1016/j.chest.2018.05.004. Epub 2018 May 17. Chest. 2018. PMID: 29778659

Patients meeting the Sepsis-3 septic shock criteria had higher in-hospital mortality (40.9% vs 33.5%; P < .0001), ICU admission (99.5% vs 89.2%; P < .001), and discharge rates to long-term care (66.3% vs 53.7%; P < .0001) than patients meeting the SIRS-based septi

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Patients meeting the Sepsis-3 septic shock criteria had higher in-hospital mortality (40.9% vs 33.5%; P < .0001), ICU admission (99.5% vs

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Prognostic Accuracy of the Quick Sequential Organ Failure Assessment for Mortality in Patients With Suspected Infection: A Systematic Review and Meta-analysis.
Fernando SM, Tran A, Taljaard M, Cheng W, Rochwerg B, Seely AJE, Perry JJ. Fernando SM, et al. Among authors: perry jj. Ann Intern Med. 2018 Feb 20;168(4):266-275. doi: 10.7326/M17-2820. Epub 2018 Feb 6. Ann Intern Med. 2018. PMID: 29404582
CONCLUSION: qSOFA had poor sensitivity and moderate specificity for short-term mortality. The SIRS criteria had sensitivity superior to that of qSOFA, supporting their use for screening of patients and as a prompt for treatment initiation. ...
CONCLUSION: qSOFA had poor sensitivity and moderate specificity for short-term mortality. The SIRS criteria had sensitivity superior …
Characteristics and outcomes for acute heart failure in elderly patients presenting to the ED.
Claret PG, Stiell IG, Yan JW, Clement CM, Rowe BH, Calder LA, Perry JJ. Claret PG, et al. Among authors: perry jj. Am J Emerg Med. 2016 Nov;34(11):2159-2166. doi: 10.1016/j.ajem.2016.08.015. Epub 2016 Aug 12. Am J Emerg Med. 2016. PMID: 27590209
In this 80-year group, history of heart failure, current medication with antiarrhythmic, acute infarction on the arrival electrocardiography, chest x-ray with pleural effusion, and urea greater than 12 mmol/L were independently associated with short-term serious adverse ev …
In this 80-year group, history of heart failure, current medication with antiarrhythmic, acute infarction on the arrival electrocardiography …
Emergency Physician Patterns Related to Anticoagulation of Patients with Recent-Onset Atrial Fibrillation and Flutter.
Misra P, Lang E, Clement CM, Brison RJ, Rowe BH, Borgundvaag B, Langhan T, Magee K, Stenstrom R, Perry JJ, Birnie D, Wells GA, Xue X, Innes G, Stiell IG. Misra P, et al. Among authors: perry jj. J Atr Fibrillation. 2013 Apr 6;5(6):645. doi: 10.4022/jafib.645. eCollection 2013 Apr-May. J Atr Fibrillation. 2013. PMID: 28496821 Free PMC article.
Guidelines strongly recommend long-term anticoagulation with warfarin for patients with newly recognized AF who have high embolic risk by virtue of a CHADS(2) (Congestive Heart Failure, Hypertension, Age >65, Diabetes, History of Stroke) score 2. ...
Guidelines strongly recommend long-term anticoagulation with warfarin for patients with newly recognized AF who have high embolic ris …
15 results