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Page 1
Anticonvulsant Primary and Secondary Prophylaxis for Acute Ischemic Stroke Patients: A Decision Analysis.
Jones FJS, Sanches PR, Smith JR, Zafar SF, Hernandez-Diaz S, Blacker D, Hsu J, Schwamm LH, Westover MB, Moura LMVR. Jones FJS, et al. Stroke. 2021 Aug;52(9):2782-2791. doi: 10.1161/STROKEAHA.120.033299. Epub 2021 Jun 15. Stroke. 2021. PMID: 34126758 Free PMC article.
METHODS: We created a decision tree to evaluate 3 strategies: (1) long-term primary prophylaxis; (2) short-term secondary prophylaxis after an early seizure with lifetime prophylaxis if persistent or late seizures (LSs) developed; and (3) long-term secondary …
METHODS: We created a decision tree to evaluate 3 strategies: (1) long-term primary prophylaxis; (2) short-term secondary prop …
Sex-specific differences in white matter microvascular integrity after ischaemic stroke.
Etherton MR, Wu O, Cougo P, Lorenzano S, Li H, Cloonan L, Bouts MJRJ, Lauer A, Arai K, Lo EH, Feske SK, Furie KL, Rost NS. Etherton MR, et al. Stroke Vasc Neurol. 2019 Sep 3;4(4):198-205. doi: 10.1136/svn-2019-000268. eCollection 2019 Dec. Stroke Vasc Neurol. 2019. PMID: 32030203 Free PMC article.
White matter microvascular integrity represents one risk factor for poor long-term functional outcomes after ischaemic stroke. The aim of the study is to characterise sex-specific differences in microvascular integrity in individuals with acute ischaemic stroke. ...
White matter microvascular integrity represents one risk factor for poor long-term functional outcomes after ischaemic stroke. The ai …
Diffuse microvascular dysfunction and loss of white matter integrity predict poor outcomes in patients with acute ischemic stroke.
Rost NS, Cougo P, Lorenzano S, Li H, Cloonan L, Bouts MJ, Lauer A, Etherton MR, Karadeli HH, Musolino PL, Copen WA, Arai K, Lo EH, Feske SK, Furie KL, Wu O. Rost NS, et al. J Cereb Blood Flow Metab. 2018 Jan;38(1):75-86. doi: 10.1177/0271678X17706449. Epub 2017 May 8. J Cereb Blood Flow Metab. 2018. PMID: 28481164 Free PMC article.
We sought to investigate the relationship between blood-brain barrier (BBB) permeability and microstructural white matter integrity, and their potential impact on long-term functional outcomes in patients with acute ischemic stroke (AIS). ...
We sought to investigate the relationship between blood-brain barrier (BBB) permeability and microstructural white matter integrity, and the …
Infarct topography and functional outcomes.
Etherton MR, Rost NS, Wu O. Etherton MR, et al. J Cereb Blood Flow Metab. 2018 Sep;38(9):1517-1532. doi: 10.1177/0271678X17700666. Epub 2017 Mar 27. J Cereb Blood Flow Metab. 2018. PMID: 28345373 Free PMC article. Review.
Acute ischemic stroke represents a major cause of long-term adult disability. Accurate prognostication of post-stroke functional outcomes is invaluable in guiding patient care, targeting early rehabilitation efforts, selecting patients for clinical research, and conveying …
Acute ischemic stroke represents a major cause of long-term adult disability. Accurate prognostication of post-stroke functional outc …
Delayed seizures after intracerebral haemorrhage.
Biffi A, Rattani A, Anderson CD, Ayres AM, Gurol EM, Greenberg SM, Rosand J, Viswanathan A. Biffi A, et al. Brain. 2016 Oct;139(Pt 10):2694-2705. doi: 10.1093/brain/aww199. Epub 2016 Aug 6. Brain. 2016. PMID: 27497491 Free PMC article.
Late seizures after intracerebral haemorrhage occur after the initial acute haemorrhagic insult subsides, and represent one of its most feared long-term sequelae. Both susceptibility to late seizures and their functional impact remain poorly characterized. ...Admission Gla …
Late seizures after intracerebral haemorrhage occur after the initial acute haemorrhagic insult subsides, and represent one of its most fear …
Risk Factors Associated With Early vs Delayed Dementia After Intracerebral Hemorrhage.
Biffi A, Bailey D, Anderson CD, Ayres AM, Gurol EM, Greenberg SM, Rosand J, Viswanathan A. Biffi A, et al. JAMA Neurol. 2016 Aug 1;73(8):969-76. doi: 10.1001/jamaneurol.2016.0955. JAMA Neurol. 2016. PMID: 27295605 Free PMC article.
IMPORTANCE: Patients who have experienced intracerebral hemorrhage (ICH) appear to develop cognitive impairment at high rates, both early after ICH and over the long term. OBJECTIVE: To identify and compare risk factors for early and delayed dementia after ICH. ...
IMPORTANCE: Patients who have experienced intracerebral hemorrhage (ICH) appear to develop cognitive impairment at high rates, both early af …
Comparing prognostic strength of acute corticospinal tract injury measured by a new diffusion tensor imaging based template approach versus common approaches.
Hirai KK, Groisser BN, Copen WA, Singhal AB, Schaechter JD. Hirai KK, et al. J Neurosci Methods. 2016 Jan 15;257:204-13. doi: 10.1016/j.jneumeth.2015.09.005. Epub 2015 Sep 16. J Neurosci Methods. 2016. PMID: 26386285 Free PMC article.
BACKGROUND: Long-term motor outcome of acute stroke patients with severe motor impairment is difficult to predict. ...
BACKGROUND: Long-term motor outcome of acute stroke patients with severe motor impairment is difficult to predict. ...
Role of Acute Lesion Topography in Initial Ischemic Stroke Severity and Long-Term Functional Outcomes.
Wu O, Cloonan L, Mocking SJ, Bouts MJ, Copen WA, Cougo-Pinto PT, Fitzpatrick K, Kanakis A, Schaefer PW, Rosand J, Furie KL, Rost NS. Wu O, et al. Stroke. 2015 Sep;46(9):2438-44. doi: 10.1161/STROKEAHA.115.009643. Epub 2015 Jul 21. Stroke. 2015. PMID: 26199314 Free PMC article.
We hypothesized that the topography of acute stroke lesions on diffusion-weighted magnetic resonance imaging may provide further information with regard to presenting stroke severity and long-term functional outcomes. METHODS: Data from a prospective stroke repository were …
We hypothesized that the topography of acute stroke lesions on diffusion-weighted magnetic resonance imaging may provide further information …
Ischemic brain injury in cerebral amyloid angiopathy.
Reijmer YD, van Veluw SJ, Greenberg SM. Reijmer YD, et al. J Cereb Blood Flow Metab. 2016 Jan;36(1):40-54. doi: 10.1038/jcbfm.2015.88. J Cereb Blood Flow Metab. 2016. PMID: 25944592 Free PMC article. Review.
A better understanding of the underlying mechanisms of ischemic brain injury in CAA will be a key step toward new interventions to improve long-term cognitive outcomes for patients with CAA....
A better understanding of the underlying mechanisms of ischemic brain injury in CAA will be a key step toward new interventions to improve l …
Sustained functional improvement by hepatocyte growth factor-like small molecule BB3 after focal cerebral ischemia in rats and mice.
Chaparro RE, Izutsu M, Sasaki T, Sheng H, Zheng Y, Sadeghian H, Qin T, von Bornstadt D, Herisson F, Duan B, Li JS, Jiang K, Pearlstein M, Pearlstein RD, Smith DE, Goldberg ID, Ayata C, Warner DS. Chaparro RE, et al. J Cereb Blood Flow Metab. 2015 Jun;35(6):1044-53. doi: 10.1038/jcbfm.2015.23. Epub 2015 Feb 25. J Cereb Blood Flow Metab. 2015. PMID: 25712497 Free PMC article.
In rats, BB3, begun 6 hours after temporary middle cerebral artery occlusion (tMCAO) reperfusion, or permanent middle cerebral artery occlusion (pMCAO) onset, and continued for 14 days consistently improved long-term neurologic function independent of sex, age, or laborato …
In rats, BB3, begun 6 hours after temporary middle cerebral artery occlusion (tMCAO) reperfusion, or permanent middle cerebral artery occlus …
15 results