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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2002 1
2006 10
2007 9
2008 16
2009 22
2010 10
2011 8
2012 1
2013 3
2014 12
2015 11
2016 9
2017 10
2018 14
2019 11
2020 12
2021 10
2022 4
2023 11
2024 4

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159 results

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Page 1
Multi-omics characterization of partial chemical reprogramming reveals evidence of cell rejuvenation.
Mitchell W, Goeminne LJE, Tyshkovskiy A, Zhang S, Chen JY, Paulo JA, Pierce KA, Choy AH, Clish CB, Gygi SP, Gladyshev VN. Mitchell W, et al. Elife. 2024 Mar 22;12:RP90579. doi: 10.7554/eLife.90579. Elife. 2024. PMID: 38517750 Free PMC article.
Partial reprogramming by cyclic short-term expression of Yamanaka factors holds promise for shifting cells to younger states and consequently delaying the onset of many diseases of aging. ...
Partial reprogramming by cyclic short-term expression of Yamanaka factors holds promise for shifting cells to younger states and cons …
Metabolite signatures associated with microRNA miR-143-3p serve as drivers of poor lung function trajectories in childhood asthma.
Mendez KM, Begum S, Tiwari A, Sharma R, Chen Q, Kelly RS, Prince N, Huang M, Kachroo P, Chu SH, Chen Y, Lee-Sarwar K, Broadhurst DI, Reinke SN, Gerszten R, Clish C, Avila L, Celedón JC, Wheelock CE, Weiss ST, McGeachie M, Lasky-Su JA. Mendez KM, et al. EBioMedicine. 2024 Apr;102:105025. doi: 10.1016/j.ebiom.2024.105025. Epub 2024 Mar 7. EBioMedicine. 2024. PMID: 38458111 Free PMC article.
BACKGROUND: Lung function trajectories (LFTs) have been shown to be an important measure of long-term health in asthma. While there is a growing body of metabolomic studies on asthma status and other phenotypes, there are no prospective studies of the relationship between …
BACKGROUND: Lung function trajectories (LFTs) have been shown to be an important measure of long-term health in asthma. While there i …
Implications of metabolism on multi-systems healthy aging across the lifespan.
Yao S, Colangelo LA, Perry AS, Marron MM, Yaffe K, Sedaghat S, Lima JAC, Tian Q, Clish CB, Newman AB, Shah RV, Murthy VL. Yao S, et al. Aging Cell. 2024 Apr;23(4):e14090. doi: 10.1111/acel.14090. Epub 2024 Jan 29. Aging Cell. 2024. PMID: 38287525 Free PMC article.
Metabolic scores for participants four decades younger in CARDIA were related to incident cardiovascular, metabolic, and neurocognitive performance, as well as long-term cardiovascular disease and mortality over three decades. Conserved metabolic states are strongly relate …
Metabolic scores for participants four decades younger in CARDIA were related to incident cardiovascular, metabolic, and neurocognitive perf …
Second international consensus report on gaps and opportunities for the clinical translation of precision diabetes medicine.
Tobias DK, Merino J, Ahmad A, Aiken C, Benham JL, Bodhini D, Clark AL, Colclough K, Corcoy R, Cromer SJ, Duan D, Felton JL, Francis EC, Gillard P, Gingras V, Gaillard R, Haider E, Hughes A, Ikle JM, Jacobsen LM, Kahkoska AR, Kettunen JLT, Kreienkamp RJ, Lim LL, Männistö JME, Massey R, Mclennan NM, Miller RG, Morieri ML, Most J, Naylor RN, Ozkan B, Patel KA, Pilla SJ, Prystupa K, Raghavan S, Rooney MR, Schön M, Semnani-Azad Z, Sevilla-Gonzalez M, Svalastoga P, Takele WW, Tam CH, Thuesen ACB, Tosur M, Wallace AS, Wang CC, Wong JJ, Yamamoto JM, Young K, Amouyal C, Andersen MK, Bonham MP, Chen M, Cheng F, Chikowore T, Chivers SC, Clemmensen C, Dabelea D, Dawed AY, Deutsch AJ, Dickens LT, DiMeglio LA, Dudenhöffer-Pfeifer M, Evans-Molina C, Fernández-Balsells MM, Fitipaldi H, Fitzpatrick SL, Gitelman SE, Goodarzi MO, Grieger JA, Guasch-Ferré M, Habibi N, Hansen T, Huang C, Harris-Kawano A, Ismail HM, Hoag B, Johnson RK, Jones AG, Koivula RW, Leong A, Leung GKW, Libman IM, Liu K, Long SA, Lowe WL Jr, Morton RW, Motala AA, Onengut-Gumuscu S, Pankow JS, Pathirana M, Pazmino S, Perez D, Petrie JR, Powe CE, Quinteros A, Jain R, Ray D, Ried-Larsen M, Saeed Z, Santhakumar V, Kanbour S, Sarkar … See abstract for full author list ➔ Tobias DK, et al. Nat Med. 2023 Oct;29(10):2438-2457. doi: 10.1038/s41591-023-02502-5. Epub 2023 Oct 5. Nat Med. 2023. PMID: 37794253 Free PMC article. Review.
Although not complete, owing to the vast literature on this topic, they revealed opportunities for the immediate or near-term clinical implementation of precision diabetes medicine; furthermore, we expose important gaps in knowledge, focusing on the need to obtain new clin …
Although not complete, owing to the vast literature on this topic, they revealed opportunities for the immediate or near-term clinica …
Ether lipid biosynthesis promotes lifespan extension and enables diverse pro-longevity paradigms in Caenorhabditis elegans.
Cedillo L, Ahsan FM, Li S, Stuhr NL, Zhou Y, Zhang Y, Adedoja A, Murphy LM, Yerevanian A, Emans S, Dao K, Li Z, Peterson ND, Watrous J, Jain M, Das S, Pukkila-Worley R, Curran SP, Soukas AA. Cedillo L, et al. Elife. 2023 Aug 22;12:e82210. doi: 10.7554/eLife.82210. Elife. 2023. PMID: 37606250 Free PMC article.
More recently, biguanides have been found to have other health benefits, including limiting the growth of various cancer cells and improving the lifespan and long-term health of several model organisms. Epidemiologic studies also suggest that metformin may increase the lif …
More recently, biguanides have been found to have other health benefits, including limiting the growth of various cancer cells and improving …
Trajectory of Gonadal Hormones in Adolescent Males up to 2 Years After Sleeve Gastrectomy.
Kaur S, Bredella MA, Misra M, Singhal V. Kaur S, et al. Obes Surg. 2023 Oct;33(10):3323-3326. doi: 10.1007/s11695-023-06759-0. Epub 2023 Aug 10. Obes Surg. 2023. PMID: 37561269
Sertoli cell function improved only slightly in SG group and did not change compared to the nonsurgical controls, and these changes were not associated with degree of weight loss. Thus, we conclude that larger and long-term follow-up studies are required to evaluate the ch …
Sertoli cell function improved only slightly in SG group and did not change compared to the nonsurgical controls, and these changes were not …
Automated body composition estimation from device-agnostic 3D optical scans in pediatric populations.
Tian IY, Wong MC, Nguyen WM, Kennedy S, McCarthy C, Kelly NN, Liu YE, Garber AK, Heymsfield SB, Curless B, Shepherd JA. Tian IY, et al. Clin Nutr. 2023 Sep;42(9):1619-1630. doi: 10.1016/j.clnu.2023.07.012. Epub 2023 Jul 18. Clin Nutr. 2023. PMID: 37481870
BACKGROUND: Excess adiposity in children is strongly correlated with obesity-related metabolic disease in adulthood, including diabetes, cardiovascular disease, and 13 types of cancer. Despite the many long-term health risks of childhood obesity, body mass index (BMI) Z-sc …
BACKGROUND: Excess adiposity in children is strongly correlated with obesity-related metabolic disease in adulthood, including diabetes, car …
Multi-omics characterization of partial chemical reprogramming reveals evidence of cell rejuvenation.
Mitchell W, Goeminne LJE, Tyshkovskiy A, Zhang S, Chen JY, Paulo JA, Pierce KA, Choy AH, Clish CB, Gygi SP, Gladyshev VN. Mitchell W, et al. bioRxiv [Preprint]. 2023 Nov 27:2023.06.30.546730. doi: 10.1101/2023.06.30.546730. bioRxiv. 2023. PMID: 37425825 Free PMC article. Updated. Preprint.
Partial reprogramming by cyclic short-term expression of Yamanaka factors holds promise for shifting cells to younger states and consequently delaying the onset of many diseases of aging. ...
Partial reprogramming by cyclic short-term expression of Yamanaka factors holds promise for shifting cells to younger states and cons …
159 results