Anti-PD-1 and Extended Half-life IL2 Synergize for Treatment of Murine Glioblastoma Independent of Host MHC Class I Expression.
Tritz ZP, Ayasoufi K, Wolf DM, Owens CA, Malo CS, Himes BT, Fain CE, Goddery EN, Yokanovich LT, Jin F, Hansen MJ, Parney IF, Wang C, Moynihan KD, Irvine DJ, Wittrup KD, Diaz Marcano RM, Vile RG, Johnson AJ.
Tritz ZP, et al.
Cancer Immunol Res. 2023 Jun 2;11(6):763-776. doi: 10.1158/2326-6066.CIR-22-0570.
Cancer Immunol Res. 2023.
PMID: 36921098
Free PMC article.
ECB generates robust immunologic responses, features of which include secondary lymphoid organ enlargement and increased activation status of both CD4 and CD8 T cells. This immunity is durable, with long-term ECB survivors able to resist GL261 rechallenge. Through employme …
ECB generates robust immunologic responses, features of which include secondary lymphoid organ enlargement and increased activation status o …