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Serum β-synuclein, neurofilament light chain and glial fibrillary acidic protein as prognostic biomarkers in moderate-to-severe acute ischemic stroke.
Barba L, Vollmuth C, Abu-Rumeileh S, Halbgebauer S, Oeckl P, Steinacker P, Kollikowski AM, Schultz C, Wolf J, Pham M, Schuhmann MK, Heuschmann PU, Haeusler KG, Stoll G, Neugebauer H, Otto M. Barba L, et al. Among authors: neugebauer h. Sci Rep. 2023 Nov 28;13(1):20941. doi: 10.1038/s41598-023-47765-7. Sci Rep. 2023. PMID: 38017278 Free PMC article.
In patients with moderate-to-severe acute ischemic stroke, serum beta-syn, NfL and GFAP levels associated with clinical and radiological scores at different timepoints and were able to predict short- and middle-term clinical outcomes....
In patients with moderate-to-severe acute ischemic stroke, serum beta-syn, NfL and GFAP levels associated with clinical and radiological sco …
High-throughput screening of spin states for transition metal complexes with spin-polarized extended tight-binding methods.
Neugebauer H, Bädorf B, Ehlert S, Hansen A, Grimme S. Neugebauer H, et al. J Comput Chem. 2023 Oct 15;44(27):2120-2129. doi: 10.1002/jcc.27185. Epub 2023 Jul 4. J Comput Chem. 2023. PMID: 37401535
The semiempirical GFNn-xTB ( n = 1, 2 ) tight-binding methods are extended with a spin-dependent energy term (spin-polarization), enabling the fast and efficient screening of different spin states for transition metal complexes. ...
The semiempirical GFNn-xTB ( n = 1, 2 ) tight-binding methods are extended with a spin-dependent energy term (spin-polarization), ena …
Large diameter hemicraniectomy does not improve long-term outcome in malignant infarction.
Lehrieder D, Müller HP, Kassubek J, Hecht N, Thomalla G, Michalski D, Gattringer T, Wartenberg KE, Schultze-Amberger J, Huttner H, Kuramatsu JB, Wunderlich S, Steiner HH, Weissenborn K, Heck S, Günther A, Schneider H, Poli S, Dohmen C, Woitzik J, Jüttler E, Neugebauer H; DESTINY-R (DEcompressive Surgery for the Treatment of malignant INfarction of the middle cerebral arterY - Registry) Study Group and IGNITE (Initiative of German NeuroIntensive Trial Engagement) Study Group. Lehrieder D, et al. Among authors: neugebauer h. J Neurol. 2023 Aug;270(8):4080-4089. doi: 10.1007/s00415-023-11766-3. Epub 2023 May 10. J Neurol. 2023. PMID: 37162579 Free PMC article. Clinical Trial.
We investigated whether this approach is associated with reduced mortality and an improved long-term functional outcome compared to a standard hemicraniectomy with a diameter of less than 14 cm (HC 14). ...
We investigated whether this approach is associated with reduced mortality and an improved long-term functional outcome compared to a …
Long-term follow-up of patients undergoing decompressive hemicraniectomy for malignant stroke: Quality of life and caregiver's burden in a real-world setting.
Hamamoto Filho PT, Gonçalves LB, Koetz NF, Silvestrin AML, Alves Júnior AC, Rocha LA, Módolo GP, de Avila MAG, Martin LC, Neugebauer H, Zanini MA, Bazan R. Hamamoto Filho PT, et al. Among authors: neugebauer h. Clin Neurol Neurosurg. 2020 Oct;197:106168. doi: 10.1016/j.clineuro.2020.106168. Epub 2020 Aug 21. Clin Neurol Neurosurg. 2020. PMID: 32861040
BACKGROUND AND PURPOSE: Decompressive hemicraniectomy is a life-saving procedure for the treatment of space-occupying middle cerebral artery infarctions (malignant stroke); however, patients may survive severely disabled. Comprehensive data on long-term sequelae outside ra …
BACKGROUND AND PURPOSE: Decompressive hemicraniectomy is a life-saving procedure for the treatment of space-occupying middle cerebral artery …
MR-imaging pattern is not a predictor of occult atrial fibrillation in patients with cryptogenic stroke.
Vollmuth C, Stoesser S, Neugebauer H, Hansel A, Dreyhaupt J, Ludolph AC, Kassubek J, Althaus K. Vollmuth C, et al. Among authors: neugebauer h. J Neurol. 2019 Dec;266(12):3058-3064. doi: 10.1007/s00415-019-09524-5. Epub 2019 Sep 11. J Neurol. 2019. PMID: 31511980 Free PMC article.
., 166 patients with embolic stroke due to AF detected for the first time by long-term ECG. Lesion patterns were evaluated with regard to affected territories, distribution (cortical, lacunar, scattered), lesion volume, and lesion size (diameter of the lesion size > 20 …
., 166 patients with embolic stroke due to AF detected for the first time by long-term ECG. Lesion patterns were evaluated with regar …
A generally applicable atomic-charge dependent London dispersion correction.
Caldeweyher E, Ehlert S, Hansen A, Neugebauer H, Spicher S, Bannwarth C, Grimme S. Caldeweyher E, et al. Among authors: neugebauer h. J Chem Phys. 2019 Apr 21;150(15):154122. doi: 10.1063/1.5090222. J Chem Phys. 2019. PMID: 31005066
In addition to the two-body part, three-body effects are described by an Axilrod-Teller-Muto term. A common many-body dispersion expansion was extensively tested, and an energy correction based on D4 polarizabilities is found to be advantageous for larger systems. ...
In addition to the two-body part, three-body effects are described by an Axilrod-Teller-Muto term. A common many-body dispersion expa …
Bio-Electrocatalytic Application of Microorganisms for Carbon Dioxide Reduction to Methane.
Schlager S, Haberbauer M, Fuchsbauer A, Hemmelmair C, Dumitru LM, Hinterberger G, Neugebauer H, Sariciftci NS. Schlager S, et al. Among authors: neugebauer h. ChemSusChem. 2017 Jan 10;10(1):226-233. doi: 10.1002/cssc.201600963. Epub 2016 Oct 28. ChemSusChem. 2017. PMID: 27792284 Free PMC article.
This study shows the biofilm formation of those microorganisms on a carbon felt electrode and the long-term performance for CO(2) reduction to CH(4) using direct electrochemical reduction. ...
This study shows the biofilm formation of those microorganisms on a carbon felt electrode and the long-term performance for CO(2) red …
Anticoagulant reversal, blood pressure levels, and anticoagulant resumption in patients with anticoagulation-related intracerebral hemorrhage.
Kuramatsu JB, Gerner ST, Schellinger PD, Glahn J, Endres M, Sobesky J, Flechsenhar J, Neugebauer H, Jüttler E, Grau A, Palm F, Röther J, Michels P, Hamann GF, Hüwel J, Hagemann G, Barber B, Terborg C, Trostdorf F, Bäzner H, Roth A, Wöhrle J, Keller M, Schwarz M, Reimann G, Volkmann J, Müllges W, Kraft P, Classen J, Hobohm C, Horn M, Milewski A, Reichmann H, Schneider H, Schimmel E, Fink GR, Dohmen C, Stetefeld H, Witte O, Günther A, Neumann-Haefelin T, Racs AE, Nueckel M, Erbguth F, Kloska SP, Dörfler A, Köhrmann M, Schwab S, Huttner HB. Kuramatsu JB, et al. Among authors: neugebauer h. JAMA. 2015 Feb 24;313(8):824-36. doi: 10.1001/jama.2015.0846. JAMA. 2015. PMID: 25710659
EXPOSURES: Reversal of anticoagulation during acute phase, systolic BP at 4 hours, and reinitiation of OAC for long-term treatment. MAIN OUTCOMES AND MEASURES: Frequency of hematoma enlargement in relation to international normalized ratio (INR) and BP. ...Propensity-match …
EXPOSURES: Reversal of anticoagulation during acute phase, systolic BP at 4 hours, and reinitiation of OAC for long-term treatment. M …
DEcompressive surgery Plus hypoTHermia for Space-Occupying Stroke (DEPTH-SOS): a protocol of a multicenter randomized controlled clinical trial and a literature review.
Neugebauer H, Kollmar R, Niesen WD, Bösel J, Schneider H, Hobohm C, Zweckberger K, Heuschmann PU, Schellinger PD, Jüttler E; DEPTH-SOS Study Group; IGNITE Study Group. Neugebauer H, et al. Int J Stroke. 2013 Jul;8(5):383-7. doi: 10.1111/ijs.12086. Int J Stroke. 2013. PMID: 23782729 Review.
DISCUSSION: The results of this trial will provide data on safety and feasibility of moderate hypothermia in addition to decompressive hemicraniectomy in malignant middle cerebral artery infarction. Furthermore, efficacy data on early mortality and long-term functional out …
DISCUSSION: The results of this trial will provide data on safety and feasibility of moderate hypothermia in addition to decompressive hemic …
Space-occupying cerebellar infarction: complications, treatment, and outcome.
Neugebauer H, Witsch J, Zweckberger K, Jüttler E. Neugebauer H, et al. Neurosurg Focus. 2013 May;34(5):E8. doi: 10.3171/2013.2.FOCUS12363. Neurosurg Focus. 2013. PMID: 23634927 Review.
Contrary to the general belief that outcome in survivors of space-occupying cerebellar stroke is usually good, recent studies suggest that for many of these patients, the long-term outcome is not good. In particular, advanced age and additional brainstem infarction seem to …
Contrary to the general belief that outcome in survivors of space-occupying cerebellar stroke is usually good, recent studies suggest that f …
12 results