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Long-term (180-Day) Outcomes in Critically Ill Patients With COVID-19 in the REMAP-CAP Randomized Clinical Trial.
Writing Committee for the REMAP-CAP Investigators; Higgins AM, Berry LR, Lorenzi E, Murthy S, McQuilten Z, Mouncey PR, Al-Beidh F, Annane D, Arabi YM, Beane A, van Bentum-Puijk W, Bhimani Z, Bonten MJM, Bradbury CA, Brunkhorst FM, Burrell A, Buzgau A, Buxton M, Charles WN, Cove M, Detry MA, Estcourt LJ, Fagbodun EO, Fitzgerald M, Girard TD, Goligher EC, Goossens H, Haniffa R, Hills T, Horvat CM, Huang DT, Ichihara N, Lamontagne F, Marshall JC, McAuley DF, McGlothlin A, McGuinness SP, McVerry BJ, Neal MD, Nichol AD, Parke RL, Parker JC, Parry-Billings K, Peters SEC, Reyes LF, Rowan KM, Saito H, Santos MS, Saunders CT, Serpa-Neto A, Seymour CW, Shankar-Hari M, Stronach LM, Turgeon AF, Turner AM, van de Veerdonk FL, Zarychanski R, Green C, Lewis RJ, Angus DC, McArthur CJ, Berry S, Derde LPG, Gordon AC, Webb SA, Lawler PR. Writing Committee for the REMAP-CAP Investigators, et al. Among authors: mouncey pr. JAMA. 2023 Jan 3;329(1):39-51. doi: 10.1001/jama.2022.23257. JAMA. 2023. PMID: 36525245 Free PMC article.
IMPORTANCE: The longer-term effects of therapies for the treatment of critically ill patients with COVID-19 are unknown. OBJECTIVE: To determine the effect of multiple interventions for critically ill adults with COVID-19 on longer-term outcomes. DESIGN, SETTING, AN …
IMPORTANCE: The longer-term effects of therapies for the treatment of critically ill patients with COVID-19 are unknown. OBJECTIVE: T …
Lower Versus Higher Exposure to Vasopressor Therapy in Vasodilatory Hypotension: A Systematic Review With Meta-Analysis.
Richards-Belle A, Hylands M, Muttalib F, Taran S, Rochwerg B, Day A, Mouncey PR, Radermacher P, Couban R, Asfar P, Adhikari NKJ, Lamontagne F. Richards-Belle A, et al. Among authors: mouncey pr. Crit Care Med. 2023 Feb 1;51(2):254-266. doi: 10.1097/CCM.0000000000005736. Epub 2022 Nov 18. Crit Care Med. 2023. PMID: 36398968 Free PMC article.
DATA EXTRACTION: The primary outcome was 90-day all-cause mortality, with seven prespecified subgroups. Secondary outcomes included shorter- and longer-term mortality, use of life-sustaining therapies, vasopressor-related complications, neurologic outcome, and quality of l …
DATA EXTRACTION: The primary outcome was 90-day all-cause mortality, with seven prespecified subgroups. Secondary outcomes included shorter- …
Renal replacement anticoagulant management: Protocol and analysis plan for an observational comparative effectiveness study of linked data sources.
Gould DW, Doidge J, Zia Sadique M, Borthwick M, Caskey FJ, Forni L, Lawrence RF, MacEwen C, Mouncey PR, Ostermann M, Harrison DA, Rowan KM, Duncan Young J, Watkinson PJ. Gould DW, et al. Among authors: mouncey pr. J Intensive Care Soc. 2022 Aug;23(3):311-317. doi: 10.1177/1751143720913417. Epub 2020 Apr 2. J Intensive Care Soc. 2022. PMID: 36033243 Free PMC article.
This shift towards regional citrate anticoagulation for CRRT is occurring with little evidence of safety or longer term effectiveness. Renal replacement anticoagulant management (RRAM) is an observational comparative effectiveness study, utilising existing data sources to …
This shift towards regional citrate anticoagulation for CRRT is occurring with little evidence of safety or longer term effectiveness …
Heparin versus citrate anticoagulation for continuous renal replacement therapy in intensive care: the RRAM observational study.
Gould DW, Doidge J, Sadique MZ, Borthwick M, Hatch R, Caskey FJ, Forni L, Lawrence RF, MacEwen C, Ostermann M, Mouncey PR, Harrison DA, Rowan KM, Young JD, Watkinson PJ. Gould DW, et al. Among authors: mouncey pr. Health Technol Assess. 2022 Feb;26(13):1-58. doi: 10.3310/ZXHI9396. Health Technol Assess. 2022. PMID: 35212260 Free PMC article.
We used routinely collected data from the Intensive Care National Audit & Research Centre Case Mix Programme national clinical audit to identify 69,001 patients who received continuous renal replacement therapy in an intensive care unit in England or Wales between 1 April 200 …
We used routinely collected data from the Intensive Care National Audit & Research Centre Case Mix Programme national clinical audit to …
Providing psychological support to people in intensive care: development and feasibility study of a nurse-led intervention to prevent acute stress and long-term morbidity.
Wade D, Als N, Bell V, Brewin C, D'Antoni D, Harrison DA, Harvey M, Harvey S, Howell D, Mouncey PR, Mythen M, Richards-Belle A, Smyth D, Weinman J, Welch J, Whitman C, Rowan KM; POPPI investigators. Wade D, et al. Among authors: mouncey pr. BMJ Open. 2018 Jul 23;8(7):e021083. doi: 10.1136/bmjopen-2017-021083. BMJ Open. 2018. PMID: 30037868 Free PMC article.
Psychological Outcomes following a nurse-led Preventative Psychological Intervention for critically ill patients (POPPI): protocol for a cluster-randomised clinical trial of a complex intervention.
Richards-Belle A, Mouncey PR, Wade D, Brewin CR, Emerson LM, Grieve R, Harrison DA, Harvey S, Howell D, Mythen M, Sadique Z, Smyth D, Weinman J, Welch J, Rowan KM; POPPI Trial Investigators. Richards-Belle A, et al. Among authors: mouncey pr. BMJ Open. 2018 Feb 8;8(2):e020908. doi: 10.1136/bmjopen-2017-020908. BMJ Open. 2018. PMID: 29439083 Free PMC article. Clinical Trial.
Little high-quality research has been conducted to evaluate psychological interventions that could alleviate longer-term psychological morbidity in the critical care unit setting. Our research team developed and piloted a nurse-led psychological intervention, aimed at redu …
Little high-quality research has been conducted to evaluate psychological interventions that could alleviate longer-term psychologica …