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Beta-Blockers after Myocardial Infarction and Preserved Ejection Fraction.
Yndigegn T, Lindahl B, Mars K, Alfredsson J, Benatar J, Brandin L, Erlinge D, Hallen O, Held C, Hjalmarsson P, Johansson P, Karlström P, Kellerth T, Marandi T, Ravn-Fischer A, Sundström J, Östlund O, Hofmann R, Jernberg T; REDUCE-AMI Investigators. Yndigegn T, et al. N Engl J Med. 2024 Apr 18;390(15):1372-1381. doi: 10.1056/NEJMoa2401479. Epub 2024 Apr 7. N Engl J Med. 2024. PMID: 38587241 Clinical Trial.
METHODS: In a parallel-group, open-label trial performed at 45 centers in Sweden, Estonia, and New Zealand, we randomly assigned patients with an acute myocardial infarction who had undergone coronary angiography and had a left ventricular ejection fraction of at least 50% to rec …
METHODS: In a parallel-group, open-label trial performed at 45 centers in Sweden, Estonia, and New Zealand, we randomly assigned patients wi …
Advances of liposomal mediated nanocarriers for the treatment of dermatophyte infections.
Ayatollahi Mousavi SA, Mokhtari A, Barani M, Izadi A, Amirbeigi A, Ajalli N, Amanizadeh A, Hadizadeh S. Ayatollahi Mousavi SA, et al. Among authors: mokhtari a. Heliyon. 2023 Aug 5;9(8):e18960. doi: 10.1016/j.heliyon.2023.e18960. eCollection 2023 Aug. Heliyon. 2023. PMID: 37583758 Free PMC article. Review.
Due to the adverse effects associated with long-term administration of antifungal drugs used for treating dermatophytic lesions like tinea unguium, there is a critical need for novel antifungal therapies that exhibit improved absorption and minimal adverse effects. ...
Due to the adverse effects associated with long-term administration of antifungal drugs used for treating dermatophytic lesions like …
Effects of Selenium and/or N-Acetyl-Cysteine Supplementation on Nonthyroidal Illness Syndrome in Hemodialysis Patients: A Factorial Randomized Controlled Trial.
Shahreki E, Kaykhaei MA, Mosallanezhad Z, Adineh Z, Mokhtari AM, Mohammadi M, Hosseini R, Bazi A. Shahreki E, et al. Among authors: mokhtari am. Pharmacology. 2022;107(9-10):480-485. doi: 10.1159/000525094. Epub 2022 Jun 10. Pharmacology. 2022. PMID: 35691282 Clinical Trial.
CONCLUSION: This trial showed that Se and/or NAC exert beneficial effects on rT3 levels in HPs. However, long-term clinical trials with a larger sample size using more appropriate biomarkers are recommended to evaluate the efficacy and safety of Se and/or NAC in HPs....
CONCLUSION: This trial showed that Se and/or NAC exert beneficial effects on rT3 levels in HPs. However, long-term clinical trials wi …
A comparative study of L4-L5-S1 and L5-S1 vertebral fusion in high-grade L5-S1 spondylolisthesis.
Rezvani M, Sabouri M, Mahmoodkhani M, Mokhtari A, Tehrani DS. Rezvani M, et al. Among authors: mokhtari a. J Craniovertebr Junction Spine. 2021 Apr-Jun;12(2):202-208. doi: 10.4103/jcvjs.jcvjs_41_21. Epub 2021 Jun 10. J Craniovertebr Junction Spine. 2021. PMID: 34194169 Free PMC article.
CONCLUSION: Both L4-L5-S1 and L5-S1 were equally beneficial in improving short-term functional outcomes for patients with high grade L5-S1 spondylolisthesis. ...
CONCLUSION: Both L4-L5-S1 and L5-S1 were equally beneficial in improving short-term functional outcomes for patients with high grade …
Application of High-Sensitivity Troponin in Suspected Myocardial Infarction.
Neumann JT, Twerenbold R, Ojeda F, Sörensen NA, Chapman AR, Shah ASV, Anand A, Boeddinghaus J, Nestelberger T, Badertscher P, Mokhtari A, Pickering JW, Troughton RW, Greenslade J, Parsonage W, Mueller-Hennessen M, Gori T, Jernberg T, Morris N, Liebetrau C, Hamm C, Katus HA, Münzel T, Landmesser U, Salomaa V, Iacoviello L, Ferrario MM, Giampaoli S, Kee F, Thorand B, Peters A, Borchini R, Jørgensen T, Söderberg S, Sans S, Tunstall-Pedoe H, Kuulasmaa K, Renné T, Lackner KJ, Worster A, Body R, Ekelund U, Kavsak PA, Keller T, Lindahl B, Wild P, Giannitsis E, Than M, Cullen LA, Mills NL, Mueller C, Zeller T, Westermann D, Blankenberg S; COMPASS-MI Study Group. Neumann JT, et al. Among authors: mokhtari a. N Engl J Med. 2019 Jun 27;380(26):2529-2540. doi: 10.1056/NEJMoa1803377. N Engl J Med. 2019. PMID: 31242362
Lower high-sensitivity troponin concentrations at presentation and smaller absolute changes during serial sampling were associated with a lower likelihood of myocardial infarction and a lower short-term risk of cardiovascular events. For example, high-sensitivity troponin …
Lower high-sensitivity troponin concentrations at presentation and smaller absolute changes during serial sampling were associated with a lo …
Controlled reoxygenation during cardiopulmonary bypass decreases markers of organ damage, inflammation, and oxidative stress in single-ventricle patients undergoing pediatric heart surgery.
Caputo M, Mokhtari A, Miceli A, Ghorbel MT, Angelini GD, Parry AJ, Suleiman SM. Caputo M, et al. Among authors: mokhtari a. J Thorac Cardiovasc Surg. 2014 Sep;148(3):792-801.e8; discussion 800-1. doi: 10.1016/j.jtcvs.2014.06.001. Epub 2014 Jun 6. J Thorac Cardiovasc Surg. 2014. PMID: 25052821 Free article. Clinical Trial.
The present study investigated the effects of controlled reoxygenation CPB on biomarkers of organ damage, inflammation, stress, and long-term functional outcomes in cyanotic patients with either a single or double ventricle during open heart surgery. ...
The present study investigated the effects of controlled reoxygenation CPB on biomarkers of organ damage, inflammation, stress, and long- …
Effects of voluntary exercise on anxiety-like behavior and voluntary morphine consumption in rat pups borne from morphine-dependent mothers during pregnancy.
Haydari S, Miladi-Gorji H, Mokhtari A, Safari M. Haydari S, et al. Among authors: mokhtari a. Neurosci Lett. 2014 Aug 22;578:50-4. doi: 10.1016/j.neulet.2014.06.026. Epub 2014 Jun 25. Neurosci Lett. 2014. PMID: 24973610
Exposure to morphine during pregnancy produced long-term effects in offspring behaviors. Recent studies have shown that voluntary exercise decreases the severity of anxiety behaviors in both morphine-dependent and withdrawn rats. ...
Exposure to morphine during pregnancy produced long-term effects in offspring behaviors. Recent studies have shown that voluntary exe …
Sternocutaneous fistulas after cardiac surgery: incidence and late outcome during a ten-year follow-up.
Steingrímsson S, Gustafsson R, Gudbjartsson T, Mokhtari A, Ingemansson R, Sjögren J. Steingrímsson S, et al. Among authors: mokhtari a. Ann Thorac Surg. 2009 Dec;88(6):1910-5. doi: 10.1016/j.athoracsur.2009.07.012. Ann Thorac Surg. 2009. PMID: 19932261
Our objective was to identify the incidence of and risk factors for SCF, and to evaluate long-term survival. METHODS: A total of 12,297 patients underwent sternotomy for cardiac surgery between January 1999 and December 2008, and 32 patients were diagnosed as having SCF du …
Our objective was to identify the incidence of and risk factors for SCF, and to evaluate long-term survival. METHODS: A total of 12,2 …
Determinants of increasing pulse pressure during 23 years' follow-up as a marker of arterial stiffness and vascular ageing.
Mokhtari A, Bellinetto-Ford L, Melander O, Nilsson PM. Mokhtari A, et al. Blood Press. 2008;17(5-6):291-7. doi: 10.1080/08037050802584313. Blood Press. 2008. PMID: 19048424
The aim was to investigate clinical characteristics of increased brachial pulse pressure (PP) during long-term follow-up (23 years) as a marker of arterial stiffness in 9704 healthy subjects. ...In conclusion, several well-known cardiovascular risk factors, such as glucose …
The aim was to investigate clinical characteristics of increased brachial pulse pressure (PP) during long-term follow-up (23 years) a …