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Comparison of weight loss induced by daily caloric restriction versus intermittent fasting (DRIFT) in individuals with obesity: study protocol for a 52-week randomized clinical trial.
Ostendorf DM, Caldwell AE, Zaman A, Pan Z, Bing K, Wayland LT, Creasy SA, Bessesen DH, MacLean P, Melanson EL, Catenacci VA. Ostendorf DM, et al. Among authors: melanson el. Trials. 2022 Aug 29;23(1):718. doi: 10.1186/s13063-022-06523-2. Trials. 2022. PMID: 36038881 Free PMC article.
DISCUSSION: Although DCR leads to modest weight loss success in the short-term, there is wide inter-individual variability in weight loss and poor long-term weight loss maintenance. Evidence-based dietary approaches to energy restriction that are effective long-t
DISCUSSION: Although DCR leads to modest weight loss success in the short-term, there is wide inter-individual variability in weight …
Multiomic Predictors of Short-Term Weight Loss and Clinical Outcomes During a Behavioral-Based Weight Loss Intervention.
Siebert JC, Stanislawski MA, Zaman A, Ostendorf DM, Konigsberg IR, Jambal P, Ir D, Bing K, Wayland L, Scorsone JJ, Lozupone CA, Görg C, Frank DN, Bessesen D, MacLean PS, Melanson EL, Catenacci VA, Borengasser SJ. Siebert JC, et al. Among authors: melanson el. Obesity (Silver Spring). 2021 May;29(5):859-869. doi: 10.1002/oby.23127. Epub 2021 Apr 3. Obesity (Silver Spring). 2021. PMID: 33811477 Free PMC article.
We hypothesized that baseline multiomic features, including DNA methylation (DNAme), metabolomics, and gut microbiome, would be predictive of short-term changes in body weight and other clinical outcomes within a comprehensive weight loss intervention. ...
We hypothesized that baseline multiomic features, including DNA methylation (DNAme), metabolomics, and gut microbiome, would be predictive o …
Compensation for cold-induced thermogenesis during weight loss maintenance and regain.
Presby DM, Jackman MR, Rudolph MC, Sherk VD, Foright RM, Houck JA, Johnson GC, Orlicky DJ, Melanson EL, Higgins JA, MacLean PS. Presby DM, et al. Among authors: melanson el. Am J Physiol Endocrinol Metab. 2019 May 1;316(5):E977-E986. doi: 10.1152/ajpendo.00543.2018. Epub 2019 Mar 26. Am J Physiol Endocrinol Metab. 2019. PMID: 30912962 Free PMC article.
Prevalence of obesity is exacerbated by low rates of successful long-term weight loss maintenance (WLM). In part, relapse from WLM to obesity is due to a reduction in energy expenditure (EE) that persists throughout WLM and relapse. ...
Prevalence of obesity is exacerbated by low rates of successful long-term weight loss maintenance (WLM). In part, relapse from WLM to …
Improving Physical Activity Through Adjunct Telerehabilitation Following Total Knee Arthroplasty: Randomized Controlled Trial Protocol.
Kline PW, Melanson EL, Sullivan WJ, Blatchford PJ, Miller MJ, Stevens-Lapsley JE, Christiansen CL. Kline PW, et al. Among authors: melanson el. Phys Ther. 2019 Jan 1;99(1):37-45. doi: 10.1093/ptj/pzy119. Phys Ther. 2019. PMID: 30329126 Free PMC article. Clinical Trial.
BACKGROUND: Physical activity remains low and nearly unchanged from preoperative levels following total knee arthroplasty (TKA), and this is thought to underlie long-term functional limitations, secondary health problems, and higher health care costs after TKA. ...Effectiv …
BACKGROUND: Physical activity remains low and nearly unchanged from preoperative levels following total knee arthroplasty (TKA), and this is …
No consistent evidence of a disproportionately low resting energy expenditure in long-term successful weight-loss maintainers.
Ostendorf DM, Melanson EL, Caldwell AE, Creasy SA, Pan Z, MacLean PS, Wyatt HR, Hill JO, Catenacci VA. Ostendorf DM, et al. Among authors: melanson el. Am J Clin Nutr. 2018 Oct 1;108(4):658-666. doi: 10.1093/ajcn/nqy179. Am J Clin Nutr. 2018. PMID: 30321282 Free PMC article.
CONCLUSIONS: We found no consistent evidence of a significantly lower REE than predicted in a sample of long-term WLMs based on predictive equations developed from NCs and OCs as well as 3 standard predictive equations. ...
CONCLUSIONS: We found no consistent evidence of a significantly lower REE than predicted in a sample of long-term WLMs based on predi …
The effects of exercise on the neuronal response to food cues.
Cornier MA, Melanson EL, Salzberg AK, Bechtell JL, Tregellas JR. Cornier MA, et al. Among authors: melanson el. Physiol Behav. 2012 Feb 28;105(4):1028-34. doi: 10.1016/j.physbeh.2011.11.023. Epub 2011 Dec 3. Physiol Behav. 2012. PMID: 22155218 Free PMC article. Clinical Trial.
Increased physical activity is associated with successful long-term weight loss maintenance due to mechanisms likely more complex than simply increased energy expenditure. ...
Increased physical activity is associated with successful long-term weight loss maintenance due to mechanisms likely more complex tha …
Nitrogen balance in older individuals in energy balance depends on timing of protein intake.
Jordan LY, Melanson EL, Melby CL, Hickey MS, Miller BF. Jordan LY, et al. Among authors: melanson el. J Gerontol A Biol Sci Med Sci. 2010 Oct;65(10):1068-76. doi: 10.1093/gerona/glq123. Epub 2010 Jul 9. J Gerontol A Biol Sci Med Sci. 2010. PMID: 20622139 Free PMC article. Clinical Trial.
To explore whether nitrogen retention can differ on an isonitrogenous diet by changing when protein is consumed, we performed a short-term study in older individuals (64.5 2.0 years) performing daily exercise while in energy balance. ...
To explore whether nitrogen retention can differ on an isonitrogenous diet by changing when protein is consumed, we performed a short-ter
Regular exercise attenuates the metabolic drive to regain weight after long-term weight loss.
MacLean PS, Higgins JA, Wyatt HR, Melanson EL, Johnson GC, Jackman MR, Giles ED, Brown IE, Hill JO. MacLean PS, et al. Among authors: melanson el. Am J Physiol Regul Integr Comp Physiol. 2009 Sep;297(3):R793-802. doi: 10.1152/ajpregu.00192.2009. Epub 2009 Jul 8. Am J Physiol Regul Integr Comp Physiol. 2009. PMID: 19587114 Free PMC article.
Effect of calcium from dairy and dietary supplements on faecal fat excretion: a meta-analysis of randomized controlled trials.
Christensen R, Lorenzen JK, Svith CR, Bartels EM, Melanson EL, Saris WH, Tremblay A, Astrup A. Christensen R, et al. Among authors: melanson el. Obes Rev. 2009 Jul;10(4):475-86. doi: 10.1111/j.1467-789X.2009.00599.x. Epub 2009 Jun 1. Obes Rev. 2009. PMID: 19493303 Review.
In conclusion, dietary calcium has the potential to increase faecal fat excretion to an extent that could be relevant for prevention of weight (re-)gain. Long-term studies are required to establish its potential contribution....
In conclusion, dietary calcium has the potential to increase faecal fat excretion to an extent that could be relevant for prevention of weig …
11 results