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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1963 1
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2004 1
2005 1
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2008 3
2009 3
2010 2
2011 2
2012 1
2013 1
2014 3
2015 1
2016 2
2019 1
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31 results

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Page 1
Evaluating the state of the science for adeno-associated virus integration: An integrated perspective.
Sabatino DE, Bushman FD, Chandler RJ, Crystal RG, Davidson BL, Dolmetsch R, Eggan KC, Gao G, Gil-Farina I, Kay MA, McCarty DM, Montini E, Ndu A, Yuan J; American Society of Gene and Cell Therapy (ASGCT) Working Group on AAV Integration. Sabatino DE, et al. Among authors: mccarty dm. Mol Ther. 2022 Aug 3;30(8):2646-2663. doi: 10.1016/j.ymthe.2022.06.004. Epub 2022 Jun 10. Mol Ther. 2022. PMID: 35690906 Free PMC article. Review.
Recombinant AAV (rAAV) vectors are used to develop therapies for many conditions given their ability to transduce multiple cell types, resulting in long-term expression of transgenes. Although most rAAV DNA typically remains episomal, some rAAV DNA becomes integrated into …
Recombinant AAV (rAAV) vectors are used to develop therapies for many conditions given their ability to transduce multiple cell types, resul …
Concomitant Tricuspid Repair in Patients with Degenerative Mitral Regurgitation.
Gammie JS, Chu MWA, Falk V, Overbey JR, Moskowitz AJ, Gillinov M, Mack MJ, Voisine P, Krane M, Yerokun B, Bowdish ME, Conradi L, Bolling SF, Miller MA, Taddei-Peters WC, Jeffries NO, Parides MK, Weisel R, Jessup M, Rose EA, Mullen JC, Raymond S, Moquete EG, O'Sullivan K, Marks ME, Iribarne A, Beyersdorf F, Borger MA, Geirsson A, Bagiella E, Hung J, Gelijns AC, O'Gara PT, Ailawadi G; CTSN Investigators. Gammie JS, et al. N Engl J Med. 2022 Jan 27;386(4):327-339. doi: 10.1056/NEJMoa2115961. Epub 2021 Nov 13. N Engl J Med. 2022. PMID: 34767705 Free PMC article. Clinical Trial.
Whether reduced progression of tricuspid regurgitation results in long-term clinical benefit can be determined only with longer follow-up. ...
Whether reduced progression of tricuspid regurgitation results in long-term clinical benefit can be determined only with longer follo …
Four-Year Visual Outcomes in the Protocol W Randomized Trial of Intravitreous Aflibercept for Prevention of Vision-Threatening Complications of Diabetic Retinopathy.
Maturi RK, Glassman AR, Josic K, Baker CW, Gerstenblith AT, Jampol LM, Meleth A, Martin DF, Melia M, Punjabi OS, Rofagha S, Salehi-Had H, Stockdale CR, Sun JK; DRCR Retina Network. Maturi RK, et al. JAMA. 2023 Feb 7;329(5):376-385. doi: 10.1001/jama.2022.25029. JAMA. 2023. PMID: 36749332 Free PMC article.
IMPORTANCE: Anti-vascular endothelial growth factor (VEGF) injections in eyes with nonproliferative diabetic retinopathy (NPDR) without center-involved diabetic macular edema (CI-DME) reduce development of vision-threatening complications from diabetes over at least 2 years, but …
IMPORTANCE: Anti-vascular endothelial growth factor (VEGF) injections in eyes with nonproliferative diabetic retinopathy (NPDR) without cent …
Durability of transgene expression after rAAV gene therapy.
Muhuri M, Levy DI, Schulz M, McCarty D, Gao G. Muhuri M, et al. Among authors: mccarty d. Mol Ther. 2022 Apr 6;30(4):1364-1380. doi: 10.1016/j.ymthe.2022.03.004. Epub 2022 Mar 10. Mol Ther. 2022. PMID: 35283274 Free PMC article. Review.
Following the initial establishment of transgene expression, it is unknown how long the therapeutic effect will last, although animal and emerging human data show that expression can be maintained for more than 10 years. The durability of therapeutic response is key to long-te …
Following the initial establishment of transgene expression, it is unknown how long the therapeutic effect will last, although animal and em …
Crossing the blood-brain-barrier with viral vectors.
Fu H, McCarty DM. Fu H, et al. Among authors: mccarty dm. Curr Opin Virol. 2016 Dec;21:87-92. doi: 10.1016/j.coviro.2016.08.006. Epub 2016 Sep 1. Curr Opin Virol. 2016. PMID: 27591676 Review.
Advances in BBB disruption have led to pre-clinical success for both global and localized gene delivery, while therapies based on receptor-mediated transcytosis have recently advanced to phase I clinical trials in humans. Both approaches show long term promise for treating …
Advances in BBB disruption have led to pre-clinical success for both global and localized gene delivery, while therapies based on receptor-m …
Efficacy of Therapist Supported Interventions from the Neonatal Intensive Care Unit to Home: A Meta-Review of Systematic Reviews.
McCarty DB, Letzkus L, Attridge E, Dusing SC. McCarty DB, et al. Clin Perinatol. 2023 Mar;50(1):157-178. doi: 10.1016/j.clp.2022.10.004. Clin Perinatol. 2023. PMID: 36868703 Review.
Infants born preterm or with complicated medical conditions requiring care in the neonatal intensive care unit (NICU) are at high risk for long-term developmental disabilities. The transition from NICU to early intervention/outpatient settings results in a disruptive gap i …
Infants born preterm or with complicated medical conditions requiring care in the neonatal intensive care unit (NICU) are at high risk for l …
Benefits of maternally-administered infant massage for mothers of hospitalized preterm infants: a scoping review.
McCarty DB, Willett S, Kimmel M, Dusing SC. McCarty DB, et al. Matern Health Neonatol Perinatol. 2023 May 3;9(1):6. doi: 10.1186/s40748-023-00151-7. Matern Health Neonatol Perinatol. 2023. PMID: 37131260 Free PMC article. Review.
Emerging evidence supports that infant massage, when administered by mothers, benefits mothers of preterm infants by reducing anxiety, stress, and depressive symptoms and improving maternal-infant interactions in the short-term, but there is limited evidence to support its …
Emerging evidence supports that infant massage, when administered by mothers, benefits mothers of preterm infants by reducing anxiety, stres …
Development and validation of health system performance measures for opioid use disorder in British Columbia, Canada.
Nosyk B, Min JE, Pearce LA, Zhou H, Homayra F, Wang L, Piske M, McCarty D, Gardner G, O'Briain W, Wood E, Daly P, Walsh T, Henry B. Nosyk B, et al. Among authors: mccarty d. Drug Alcohol Depend. 2022 Apr 1;233:109375. doi: 10.1016/j.drugalcdep.2022.109375. Epub 2022 Feb 24. Drug Alcohol Depend. 2022. PMID: 35231716
CONCLUSIONS: We identified a range of priorities to improve the quality of care for PWOUD, with critical gaps in linkage to care through acute care settings and long-term engagement in OAT. The proposed measures can be derived for geographic and clinical subgroups and upda …
CONCLUSIONS: We identified a range of priorities to improve the quality of care for PWOUD, with critical gaps in linkage to care through acu …
Immunogenicity and inflammatory properties of respiratory syncytial virus attachment G protein in cotton rats.
Martinez ME, Capella Gonzalez C, Huey D, Peeples ME, McCarty D, Niewiesk S. Martinez ME, et al. Among authors: mccarty d. PLoS One. 2021 Feb 18;16(2):e0246770. doi: 10.1371/journal.pone.0246770. eCollection 2021. PLoS One. 2021. PMID: 33600439 Free PMC article.
We found no increase in pulmonary inflammation as determined by histology and bronchoalveolar lavage after inoculation of AAVs expressing the membrane bound G protein, the secreted G protein or the complete G protein gene which expresses both forms. The long-term low-level …
We found no increase in pulmonary inflammation as determined by histology and bronchoalveolar lavage after inoculation of AAVs expressing th …
31 results