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Long-term survival and functional outcomes of critically ill patients with hematologic malignancies: a Canadian multicenter prospective study.
Munshi L, Dumas G, Rochwerg B, Shoukat F, Detsky M, Fergusson DA, Ferreyro BL, Heffernan P, Herridge M, Magder S, Minden M, Patel R, Qureshi S, Schimmer A, Thyagu S, Wang HT, Mehta S. Munshi L, et al. Among authors: magder s. Intensive Care Med. 2024 Apr;50(4):561-572. doi: 10.1007/s00134-024-07349-z. Epub 2024 Mar 11. Intensive Care Med. 2024. PMID: 38466402
PURPOSE: Patients with hematologic malignancy (HM) commonly develop critical illness. Their long-term survival and functional outcomes have not been well described. ...
PURPOSE: Patients with hematologic malignancy (HM) commonly develop critical illness. Their long-term survival and functional outcome …
Right Ventricular Limitation: A Tale of Two Elastances.
Magder S, Slobod D, Assanangkornchai N. Magder S, et al. Am J Respir Crit Care Med. 2023 Mar 15;207(6):678-692. doi: 10.1164/rccm.202106-1564SO. Am J Respir Crit Care Med. 2023. PMID: 36257049
These two elastances limit RV filling and stroke volume and consequently limit left ventricular stroke volume. We emphasize the use of the term "RV limitation" and argue that limitation of RV filling is the primary pathophysiological process by which the RV causes hemodyna …
These two elastances limit RV filling and stroke volume and consequently limit left ventricular stroke volume. We emphasize the use of the …
Long-term general and cardiovascular safety of tiotropium/olodaterol in patients with moderate to very severe chronic obstructive pulmonary disease.
Buhl R, Magder S, Bothner U, Tetzlaff K, Voß F, Loaiza L, Vogelmeier CF, McGarvey L. Buhl R, et al. Among authors: magder s. Respir Med. 2017 Jan;122:58-66. doi: 10.1016/j.rmed.2016.11.011. Epub 2016 Nov 14. Respir Med. 2017. PMID: 27993292 Free article. Clinical Trial.
BACKGROUND: Long-term safety, particularly cardiovascular safety, is of special interest in maintenance treatment of chronic obstructive pulmonary disease (COPD) with long-acting beta(2)-agonists and long-acting muscarinic antagonists, given potential cardiovascular effect …
BACKGROUND: Long-term safety, particularly cardiovascular safety, is of special interest in maintenance treatment of chronic obstruct …
One-Year Safety of Olodaterol Once Daily via Respimat® in Patients with GOLD 2-4 Chronic Obstructive Pulmonary Disease: Results of a Pre-Specified Pooled Analysis.
McGarvey L, Niewoehner D, Magder S, Sachs P, Tetzlaff K, Hamilton A, Korducki L, Bothner U, Vogelmeier C, Koch A, Ferguson GT. McGarvey L, et al. Among authors: magder s. COPD. 2015;12(5):484-93. doi: 10.3109/15412555.2014.991864. Epub 2015 Feb 18. COPD. 2015. PMID: 25692310 Free PMC article. Clinical Trial.
The novel long-acting beta2-agonist olodaterol demonstrated an acceptable safety profile in short-term phase II clinical studies. This analysis of four randomized, double-blind, placebo-controlled, parallel-group, phase III studies (1222.11, NCT00782210; 1222.12, NCT007825 …
The novel long-acting beta2-agonist olodaterol demonstrated an acceptable safety profile in short-term phase II clinical studies. Thi …
Cause-specific mortality adjudication in the UPLIFT® COPD trial: findings and recommendations.
McGarvey LP, Magder S, Burkhart D, Kesten S, Liu D, Manuel RC, Niewoehner DE. McGarvey LP, et al. Among authors: magder s. Respir Med. 2012 Apr;106(4):515-21. doi: 10.1016/j.rmed.2011.10.009. Epub 2011 Nov 18. Respir Med. 2012. PMID: 22100536 Free article. Clinical Trial.
Mortality is an important endpoint in chronic obstructive pulmonary disease (COPD) trials, although accurately determining cause of death is difficult. In the Understanding the Potential Long-term Impacts on Function with Tiotropium (UPLIFT) trial, a mortality adjudication …
Mortality is an important endpoint in chronic obstructive pulmonary disease (COPD) trials, although accurately determining cause of death is …
The effects of changes in ventilation and cardiac output on expired nitric oxide.
Mehta S, Magder S, Levy RD. Mehta S, et al. Among authors: magder s. Chest. 1997 Apr;111(4):1045-9. doi: 10.1378/chest.111.4.1045. Chest. 1997. PMID: 9106587
Changes in VE over a physiologic range significantly affect the measurement of NO in expired gas, whereas short-term changes in cardiac output do not. To facilitate comparison between studies, we suggest that the measurement of expired NO should be reported in conjunction …
Changes in VE over a physiologic range significantly affect the measurement of NO in expired gas, whereas short-term changes in cardi …