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Diagnosis and investigation of suspected haemophagocytic lymphohistiocytosis in adults: 2023 Hyperinflammation and HLH Across Speciality Collaboration (HiHASC) consensus guideline.
Cox MF, Mackenzie S, Low R, Brown M, Sanchez E, Carr A, Carpenter B, Bishton M, Duncombe A, Akpabio A, Kulasekararaj A, Sin FE, Jones A, Kavirayani A, Sen ES, Quick V, Dulay GS, Clark S, Bauchmuller K, Tattersall RS, Manson JJ; HiHASC group. Cox MF, et al. Among authors: mackenzie s. Lancet Rheumatol. 2024 Jan;6(1):e51-e62. doi: 10.1016/S2665-9913(23)00273-4. Epub 2023 Nov 29. Lancet Rheumatol. 2024. PMID: 38258680 Review.
HLH should be considered in any acutely unwell patient not responding to treatment as expected, with prompt assessment to look for what we term the three Fs-fever, falling blood counts, and raised ferritin. ...
HLH should be considered in any acutely unwell patient not responding to treatment as expected, with prompt assessment to look for what we …
Circadian rhythm of preferred temperature in fish: Behavioural thermoregulation linked to daily photocycles in zebrafish and Nile tilapia.
Vera LM, de Alba G, Santos S, Szewczyk TM, Mackenzie SA, Sánchez-Vázquez FJ, Rey Planellas S. Vera LM, et al. Among authors: mackenzie sa. J Therm Biol. 2023 Apr;113:103544. doi: 10.1016/j.jtherbio.2023.103544. Epub 2023 Mar 21. J Therm Biol. 2023. PMID: 37055103 Free article.
Each species was allowed to freely choose their preferred temperature during the 24h cycle over a long-term period. Both species displayed strikingly consistent temporal daily rhythms of thermal preference with higher temperatures being selected during the second half of t …
Each species was allowed to freely choose their preferred temperature during the 24h cycle over a long-term period. Both species disp …
Intervention rates are low after direct discharge from the Edinburgh trauma triage clinic: Outcomes of 6,688 patients.
Mackenzie S, Riddoch F, Martin D, McCann C, Bayram J, Duckworth A, White T. Mackenzie S, et al. Injury. 2022 Oct;53(10):3269-3275. doi: 10.1016/j.injury.2022.07.039. Epub 2022 Jul 28. Injury. 2022. PMID: 35965131
AIM: The Edinburgh Trauma Triage clinic (TTC) is an established form of Virtual Fracture clinic (VFC) that permits the direct discharge of simple, isolated fractures from the Emergency Department (ED). Small, short-term cohort studies of similar systems have been published …
AIM: The Edinburgh Trauma Triage clinic (TTC) is an established form of Virtual Fracture clinic (VFC) that permits the direct discharge of s …
Investigating the Effect of an Oxytetracycline Treatment on the Gut Microbiome and Antimicrobial Resistance Gene Dynamics in Nile Tilapia (Oreochromis niloticus).
Payne CJ, Turnbull JF, MacKenzie S, Crumlish M. Payne CJ, et al. Among authors: mackenzie s. Antibiotics (Basel). 2021 Oct 6;10(10):1213. doi: 10.3390/antibiotics10101213. Antibiotics (Basel). 2021. PMID: 34680794 Free PMC article.
The findings from this study demonstrate that antibiotic treatment can exert selective pressures on the gut microbiome of fish in favour of resistant populations, which may have long-term impacts on fish health....
The findings from this study demonstrate that antibiotic treatment can exert selective pressures on the gut microbiome of fish in favour of …
Outcome following mini-open lower limb fasciotomy for chronic exertional compartment syndrome.
Oliver WM, Rhatigan D, Mackenzie SP, White TO, Duckworth AD, Molyneux SG. Oliver WM, et al. Among authors: mackenzie sp. Eur J Orthop Surg Traumatol. 2022 Jan;32(1):27-36. doi: 10.1007/s00590-021-02919-z. Epub 2021 Mar 6. Eur J Orthop Surg Traumatol. 2022. PMID: 33675406 Free PMC article.
Eight per cent (n = 3/37) required revision fasciotomy for recurrent leg pain. At longer-term follow-up, 30% (n = 8/27) were asymptomatic and another 56% (n = 15/27) reported improved symptoms. ...
Eight per cent (n = 3/37) required revision fasciotomy for recurrent leg pain. At longer-term follow-up, 30% (n = 8/27) were asymptom …
Massive open online course for type 2 diabetes self-management: adapting education in the COVID-19 era.
Mackenzie SC, Cumming KM, Garrell D, Brodie D, Wilson L, Mehar S, Cunningham SG, Bickerton A, Wake DJ. Mackenzie SC, et al. BMJ Innov. 2020 Dec 29;7(1):141-147. doi: 10.1136/bmjinnov-2020-000526. Epub 2020 Nov 16. BMJ Innov. 2020. PMID: 37556268
METHODS: We aimed to evaluate user uptake, dropout, acceptability, satisfaction, perceived short-term knowledge gain and health benefits/behaviour changes in relation to a free massive open online course (MOOC) in diabetes self-management education, created and delivered d …
METHODS: We aimed to evaluate user uptake, dropout, acceptability, satisfaction, perceived short-term knowledge gain and health benef …
Percutaneous reduction and fixation of low energy Lisfranc injuries results in better outcome compared to open reduction and internal fixation: Results from a matched case-control study with minimum 12 months follow up.
Chen P, Ng N, Snowden G, Mackenzie SP, Nicholson JA, Amin AK. Chen P, et al. Among authors: mackenzie sp. Injury. 2021 Apr;52(4):1042-1047. doi: 10.1016/j.injury.2020.10.081. Epub 2020 Oct 18. Injury. 2021. PMID: 33268080
CONCLUSIONS: PRIF of low energy Lisfranc injures is a safe, minimally invasive technique and is associated with better mid-term clinical outcomes compared to ORIF....
CONCLUSIONS: PRIF of low energy Lisfranc injures is a safe, minimally invasive technique and is associated with better mid-term clini …
Long-Term Outcomes of Fasciotomy for Acute Compartment Syndrome After a Fracture of the Tibial Diaphysis.
MacKenzie SA, Carter TH, MacDonald D, White TO, Duckworth AD. MacKenzie SA, et al. J Orthop Trauma. 2020 Oct;34(10):512-517. doi: 10.1097/BOT.0000000000001786. J Orthop Trauma. 2020. PMID: 32675711
The primary long-term outcome measure was the patient-reported EuroQol-5D-3L (EQ-5D). Secondary long-term outcomes included the Oxford Knee Score, the Manchester-Oxford Foot Questionnaire, and satisfaction. ...
The primary long-term outcome measure was the patient-reported EuroQol-5D-3L (EQ-5D). Secondary long-term outcomes included th …
42 results