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Gantenerumab: a novel human anti-Aβ antibody demonstrates sustained cerebral amyloid-β binding and elicits cell-mediated removal of human amyloid-β.
J Alzheimers Dis. 2012;28(1):49-69. doi: 10.3233/JAD-2011-110977.
J Alzheimers Dis. 2012.
PMID: 21955818
In functional assays gantenerumab induced cellular phagocytosis of human amyloid-beta deposits in AD brain slices when co-cultured with primary human macrophages and neutralized oligomeric Abeta42-mediated inhibitory effects on long-term potentiation in rat brain. In APP75 …
In functional assays gantenerumab induced cellular phagocytosis of human amyloid-beta deposits in AD brain slices when co-cultured with prim …
Evolution of collagen arthritis in mice is arrested by treatment with anti-tumour necrosis factor (TNF) antibody or a recombinant soluble TNF receptor.
Piguet PF, Grau GE, Vesin C, Loetscher H, Gentz R, Lesslauer W.
Piguet PF, et al. Among authors: loetscher h.
Immunology. 1992 Dec;77(4):510-4.
Immunology. 1992.
PMID: 1337334
Free PMC article.
A soluble form of the human recombinant TNF receptor type-beta (rsTNFR-beta), continuously infused at a rate of 20 micrograms/day during the second and third week after immunization, also had a long-term protective effect. Anti-TNF antibody had no effect upon the productio …
A soluble form of the human recombinant TNF receptor type-beta (rsTNFR-beta), continuously infused at a rate of 20 micrograms/day during the …
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