HDAC6-dependent deacetylation of NGF dictates its ubiquitination and maintains primordial follicle dormancy.
Zhang T, Tong Y, Zhu R, Liang Y, Zhang J, Hu C, He M, Hu Z, Shen Z, Niu J, Zhang J, Yu Y, Jin B, Lei S, Zeng Z, Wu Y, Cheng Z, Xiao Z, Guo B, Zhao S, Xu G, Pan W, Chen T.
Zhang T, et al. Among authors: liang y.
Theranostics. 2024 Mar 25;14(6):2345-2366. doi: 10.7150/thno.95164. eCollection 2024.
Theranostics. 2024.
PMID: 38646645
Free PMC article.
Overexpression of Hdac6 delayed the rate of primordial follicle activation, thereby prolonging the mouse reproductive lifespan. Short-term inhibition of HDAC6 promoted primordial follicle activation and follicular development in humans and mice. ...
Overexpression of Hdac6 delayed the rate of primordial follicle activation, thereby prolonging the mouse reproductive lifespan. Short-ter …