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Long-Term Outcome of Severe Metabolic Acidemia in ICU Patients, a BICAR-ICU Trial Post Hoc Analysis.
Bendiab E, Garnier F, Soler M, Fosset M, Jaber S, Molinari N, Jung B; BICAR-ICU Investigators. Bendiab E, et al. Crit Care Med. 2023 Jan 1;51(1):e1-e12. doi: 10.1097/CCM.0000000000005706. Epub 2022 Nov 8. Crit Care Med. 2023. PMID: 36351174 Clinical Trial.
OBJECTIVES: Long-term prognosis of ICU survivors is a major issue. Severe acidemia upon ICU admission is associated with very high short-term mortality. Since the long-term prognosis of these patients is unknown, we aimed to determine the long-term hea …
OBJECTIVES: Long-term prognosis of ICU survivors is a major issue. Severe acidemia upon ICU admission is associated with very high sh …
Determinants of long-term outcome in ICU survivors: results from the FROG-ICU study.
Gayat E, Cariou A, Deye N, Vieillard-Baron A, Jaber S, Damoisel C, Lu Q, Monnet X, Rennuit I, Azoulay E, Léone M, Oueslati H, Guidet B, Friedman D, Tesnière A, Sonneville R, Montravers P, Pili-Floury S, Lefrant JY, Duranteau J, Laterre PF, Brechot N, Chevreul K, Michel M, Cholley B, Legrand M, Launay JM, Vicaut E, Singer M, Resche-Rigon M, Mebazaa A. Gayat E, et al. Among authors: lefrant jy. Crit Care. 2018 Jan 18;22(1):8. doi: 10.1186/s13054-017-1922-8. Crit Care. 2018. PMID: 29347987 Free PMC article. Clinical Trial.
BACKGROUND: Intensive care unit (ICU) survivors have reduced long-term survival compared to the general population. Identifying parameters at ICU discharge that are associated with poor long-term outcomes may prove useful in targeting an at-risk population. ...CONCL …
BACKGROUND: Intensive care unit (ICU) survivors have reduced long-term survival compared to the general population. Identifying param …
Long-term mortality and quality of life after trauma: an ancillary study from the prospective multicenter trial FROG-ICU.
Pastene B, Cinotti R, Gayat E, Duranteau J, Lu Q, Montravers P, Pili-Floury S, Rennuit I, Mebazaa A, Leone M; FROG-ICU investigators. Pastene B, et al. Eur J Trauma Emerg Surg. 2021 Apr;47(2):461-466. doi: 10.1007/s00068-019-01176-4. Epub 2019 Jun 18. Eur J Trauma Emerg Surg. 2021. PMID: 31214722
INTRODUCTION: The long-term outcomes of intensive care unit (ICU) patients are known to be worse than those of the general population, but they are poorly known in severe trauma patients. We conducted an ancillary examination of the FROG-ICU study to identify risk factors …
INTRODUCTION: The long-term outcomes of intensive care unit (ICU) patients are known to be worse than those of the general population …
Analgesic efficacy of erector spinae plane blocks for lumbar spine surgery: a randomized double-blind controlled clinical trial.
Avis G, Gricourt Y, Vialatte PB, Meunier V, Perin M, Simon N, Claret PG, El Fertit H, Lefrant JY, Bertrand M, Cuvillon P. Avis G, et al. Among authors: lefrant jy. Reg Anesth Pain Med. 2022 Jul 21:rapm-2022-103737. doi: 10.1136/rapm-2022-103737. Online ahead of print. Reg Anesth Pain Med. 2022. PMID: 35863786
DISCUSSION: Erector spinae plane block used in conjunction with 'Enhance Recovery After Surgery' and multimodal analgesia protocols provides limited reduction in opioid consumption and no long-term benefits. TRIAL REGISTRATION NUMBER: EudraCT 2019-001678-26....
DISCUSSION: Erector spinae plane block used in conjunction with 'Enhance Recovery After Surgery' and multimodal analgesia protocols provides …
Gender and survival of critically ill patients: results from the FROG-ICU study.
Hollinger A, Gayat E, Féliot E, Paugam-Burtz C, Fournier MC, Duranteau J, Lefrant JY, Leone M, Jaber S, Mebazaa A, Arrigo M; FROG ICU study investigators. Hollinger A, et al. Among authors: lefrant jy. Ann Intensive Care. 2019 Mar 29;9(1):43. doi: 10.1186/s13613-019-0514-y. Ann Intensive Care. 2019. PMID: 30927096 Free PMC article.
This study aimed to test the independent association of gender and long-term survival of ICU patients. MATERIALS AND METHODS: FROG-ICU was a prospective, observational, multi-center cohort designed to investigate the long-term mortality of critically ill adult patie …
This study aimed to test the independent association of gender and long-term survival of ICU patients. MATERIALS AND METHODS: FROG-IC …
Effect of Human Recombinant Alkaline Phosphatase on 7-Day Creatinine Clearance in Patients With Sepsis-Associated Acute Kidney Injury: A Randomized Clinical Trial.
Pickkers P, Mehta RL, Murray PT, Joannidis M, Molitoris BA, Kellum JA, Bachler M, Hoste EAJ, Hoiting O, Krell K, Ostermann M, Rozendaal W, Valkonen M, Brealey D, Beishuizen A, Meziani F, Murugan R, de Geus H, Payen D, van den Berg E, Arend J; STOP-AKI Investigators. Pickkers P, et al. JAMA. 2018 Nov 20;320(19):1998-2009. doi: 10.1001/jama.2018.14283. JAMA. 2018. PMID: 30357272 Free PMC article. Clinical Trial.
IMPORTANCE: Sepsis-associated acute kidney injury (AKI) adversely affects long-term kidney outcomes and survival. Administration of the detoxifying enzyme alkaline phosphatase may improve kidney function and survival. ...CONCLUSIONS AND RELEVANCE: Among patients who were c …
IMPORTANCE: Sepsis-associated acute kidney injury (AKI) adversely affects long-term kidney outcomes and survival. Administration of t …
Corticotherapy for traumatic brain-injured patients--the Corti-TC trial: study protocol for a randomized controlled trial.
Asehnoune K, Roquilly A, Sebille V; Corti-TC trial group. Asehnoune K, et al. Trials. 2011 Oct 14;12:228. doi: 10.1186/1745-6215-12-228. Trials. 2011. PMID: 21999663 Free PMC article. Clinical Trial.
DISCUSSION: The CORTI-TC trial is the first randomized controlled trial powered to investigate whether hydrocortisone with fludrocortisone in TBI patients with CI prevent HAP and improve long term recovery. TRIAL REGISTRATION: NCT01093261....
DISCUSSION: The CORTI-TC trial is the first randomized controlled trial powered to investigate whether hydrocortisone with fludrocortisone i …
Assessment of neutrophil gelatinase-associated lipocalin in the brain-dead organ donor to predict immediate graft function in kidney recipients: a prospective, multicenter study.
Muller L, Nicolas-Robin A, Bastide S, Martinez O, Louart G, Colavolpe JC, Vachiery F, Alonso S, Lefrant JY, Riou B; AzuRea Group. Muller L, et al. Among authors: lefrant jy. Anesthesiology. 2015 Jan;122(1):96-105. doi: 10.1097/ALN.0000000000000497. Anesthesiology. 2015. PMID: 25611655 Free article.
BACKGROUND: Delayed graft function is a major determinant of long-term renal allograft survival. Despite considerable efforts to improve donor selection and matching, incidence of delayed graft function remains close to 25%. ...
BACKGROUND: Delayed graft function is a major determinant of long-term renal allograft survival. Despite considerable efforts to impr …