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The risk of major bleeding in patients with factor V Leiden or prothrombin G20210A gene mutation while on extended anticoagulant treatment for venous thromboembolism.
Caiano L, Kovacs MJ, Lazo-Langner A, Anderson DR, Kahn SR, Shah V, Kaatz S, Zide RS, Schulman S, Chagnon I, Mallick R, Rodger MA, Wells PS. Caiano L, et al. Among authors: lazo langner a. J Thromb Haemost. 2023 Mar;21(3):553-558. doi: 10.1016/j.jtha.2022.12.021. Epub 2022 Dec 30. J Thromb Haemost. 2023. PMID: 36710196 Free article.
METHODS: This multicentre, multinational, prospective cohort study evaluated adults receiving long-term anticoagulants after a VTE event. We analyzed the incidence of major bleeding as the primary outcome, according to the genotype for FVL and PGM (wild-type and heterozygo …
METHODS: This multicentre, multinational, prospective cohort study evaluated adults receiving long-term anticoagulants after a VTE ev …
Clinical characteristics, multiorgan dysfunction and outcomes of patients with COVID-19: a prospective case series.
Honarmand K, Fiorini K, Chakraborty D, Gillett D, Desai K, Martin C, Bosma KJ, Slessarev M, Ball IM, Mele T, LeBlanc D, Elsayed S, Lazo-Langner A, Nicholson MJ, Arntfield R, Basmaji J. Honarmand K, et al. Among authors: lazo langner a. CMAJ Open. 2022 Jul 19;10(3):E675-E684. doi: 10.9778/cmajo.20210151. Print 2022 Jul-Sep. CMAJ Open. 2022. PMID: 35853662 Free PMC article.
BACKGROUND: Characterizing the multiorgan manifestations and outcomes of patients hospitalized with COVID-19 will inform resource requirements to address the long-term burden of this disease. We conducted a descriptive analysis using prospectively collected data to describ …
BACKGROUND: Characterizing the multiorgan manifestations and outcomes of patients hospitalized with COVID-19 will inform resource requiremen …
Large expert-curated database for benchmarking document similarity detection in biomedical literature search.
Brown P; RELISH Consortium; Zhou Y. Brown P, et al. Database (Oxford). 2019 Jan 1;2019:baz085. doi: 10.1093/database/baz085. Database (Oxford). 2019. PMID: 33326193 Free PMC article.
We further show that the three representative baseline methods used to generate recommended articles for evaluation (Okapi Best Matching 25, Term Frequency-Inverse Document Frequency and PubMed Related Articles) had similar overall performances. ...
We further show that the three representative baseline methods used to generate recommended articles for evaluation (Okapi Best Matching 25, …
Patient preferences for stopping tyrosine kinase inhibitors in chronic myeloid leukemia.
Sanford D, Kyle R, Lazo-Langner A, Xenocostas A, Chin-Yee I, Howson-Jan K, Hsia C. Sanford D, et al. Among authors: lazo langner a. Curr Oncol. 2014 Apr;21(2):e241-9. doi: 10.3747/co.21.1736. Curr Oncol. 2014. PMID: 24764709 Free PMC article.
Participant responses suggest that the idea of stopping tki use is appealing to many patients if there is a chance of long-term stable disease and a high probability of response upon restarting a tki. ...
Participant responses suggest that the idea of stopping tki use is appealing to many patients if there is a chance of long-term stabl …
Development of a clinical prediction rule for risk stratification of recurrent venous thromboembolism in patients with cancer-associated venous thromboembolism.
Louzada ML, Carrier M, Lazo-Langner A, Dao V, Kovacs MJ, Ramsay TO, Rodger MA, Zhang J, Lee AY, Meyer G, Wells PS. Louzada ML, et al. Among authors: lazo langner a. Circulation. 2012 Jul 24;126(4):448-54. doi: 10.1161/CIRCULATIONAHA.111.051920. Epub 2012 Jun 7. Circulation. 2012. PMID: 22679142 Clinical Trial.
BACKGROUND: Long-term low-molecular-weight heparin (LMWH) is the current standard for treatment of venous thromboembolism (VTE) in cancer patients. ...
BACKGROUND: Long-term low-molecular-weight heparin (LMWH) is the current standard for treatment of venous thromboembolism (VTE) in ca …
Oral rivaroxaban for the treatment of symptomatic pulmonary embolism.
EINSTEIN–PE Investigators; Büller HR, Prins MH, Lensin AW, Decousus H, Jacobson BF, Minar E, Chlumsky J, Verhamme P, Wells P, Agnelli G, Cohen A, Berkowitz SD, Bounameaux H, Davidson BL, Misselwitz F, Gallus AS, Raskob GE, Schellong S, Segers A. EINSTEIN–PE Investigators, et al. N Engl J Med. 2012 Apr 5;366(14):1287-97. doi: 10.1056/NEJMoa1113572. Epub 2012 Mar 26. N Engl J Med. 2012. PMID: 22449293 Free article. Clinical Trial.
CONCLUSIONS: A fixed-dose regimen of rivaroxaban alone was noninferior to standard therapy for the initial and long-term treatment of pulmonary embolism and had a potentially improved benefit-risk profile. ...
CONCLUSIONS: A fixed-dose regimen of rivaroxaban alone was noninferior to standard therapy for the initial and long-term treatment of …
Long-term dalteparin in pregnancy not associated with a decrease in bone mineral density: substudy of a randomized controlled trial.
Rodger MA, Kahn SR, Cranney A, Hodsman A, Kovacs MJ, Clement AM, Lazo-Langner A, Hague WM; TIPPS investigators. Rodger MA, et al. Among authors: lazo langner a. J Thromb Haemost. 2007 Aug;5(8):1600-6. doi: 10.1111/j.1538-7836.2007.02634.x. J Thromb Haemost. 2007. PMID: 17663731 Free article. Clinical Trial.
BACKGROUND: The risk of decreased bone mineral density (BMD) with prophylactic dose long-term low-molecular-weight heparin (LMWH) is unknown. OBJECTIVES: We sought to determine whether long-term prophylactic dalteparin in pregnancy leads to loss of BMD. ...Similarly …
BACKGROUND: The risk of decreased bone mineral density (BMD) with prophylactic dose long-term low-molecular-weight heparin (LMWH) is …
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