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Evaluating the effectiveness of a multifaceted intervention to reduce low-value care in adults hospitalized following trauma: a protocol for a pragmatic cluster randomized controlled trial.
Moore L, Bérubé M, Belcaid A, Turgeon AF, Taljaard M, Fowler R, Yanchar N, Mercier É, Paquet J, Stelfox HT, Archambault P, Berthelot S, Guertin JR, Haas B, Ivers N, Grimshaw J, Lapierre A, Ouyang Y, Sykes M, Witteman H, Lessard-Bonaventure P, Gabbe B, Lauzier F; Canadian Traumatic Brain Injury Research Consortium (CTRC). Moore L, et al. Among authors: lauzier f. Implement Sci. 2023 Jul 7;18(1):27. doi: 10.1186/s13012-023-01279-y. Implement Sci. 2023. PMID: 37420284 Free PMC article.
DISCUSSION: On completion of the cRCT, if the intervention is effective and cost-effective, the multifaceted intervention will be integrated into trauma systems across Canada. Medium and long-term benefits may include a reduction in adverse events for patients and an incre …
DISCUSSION: On completion of the cRCT, if the intervention is effective and cost-effective, the multifaceted intervention will be integrated …
Sex differences in thromboprophylaxis of the critically ill: a secondary analysis of a randomized trial.
Burns KEA, Heels-Ansdell D, Thabane L, Kahn SR, Lauzier F, Mehta S, Ostermann M, Bhuptani P, Crowther MA, Finfer S, Cook DJ; PROTECT Investigators, the Canadian Critical Care Trials Group, and the Australian and New Zealand Intensive Care Society Clinical Trials Group. Burns KEA, et al. Among authors: lauzier f. Can J Anaesth. 2023 Jun;70(6):1008-1018. doi: 10.1007/s12630-023-02457-8. Epub 2023 Jun 13. Can J Anaesth. 2023. PMID: 37310606 Clinical Trial. English.
METHODS: We conducted unadjusted analyses using Cox proportional hazards analysis, stratified by centre and admission diagnostic category, including sex, treatment, and an interaction term. Additionally, we performed adjusted analyses and assessed the credibility of our fi …
METHODS: We conducted unadjusted analyses using Cox proportional hazards analysis, stratified by centre and admission diagnostic category, i …
Interdisciplinary strategies to prevent long-term and detrimental opioid use following trauma: a stakeholder consensus study.
Bérubé M, Côté C, Gagnon MA, Moore L, Tremblay L, Turgeon AF, Evans D, Berry G, Turcotte V, Belzile ÉL, Dale C, Orrantia E, Verret M, Dercksen J, Martel MO, Dupuis S, Chatillon CE, Lauzier F. Bérubé M, et al. Among authors: lauzier f. Pain Med. 2023 Aug 1;24(8):933-940. doi: 10.1093/pm/pnad037. Pain Med. 2023. PMID: 36944264 Free PMC article.
The objectives of this study were to select interdisciplinary strategies to prevent long-term, detrimental opioid use in trauma patients for further evaluation and to identify implementation considerations. ...These strategies could ultimately decrease the burden associate …
The objectives of this study were to select interdisciplinary strategies to prevent long-term, detrimental opioid use in trauma patie …
Long-term (180-Day) Outcomes in Critically Ill Patients With COVID-19 in the REMAP-CAP Randomized Clinical Trial.
Writing Committee for the REMAP-CAP Investigators; Higgins AM, Berry LR, Lorenzi E, Murthy S, McQuilten Z, Mouncey PR, Al-Beidh F, Annane D, Arabi YM, Beane A, van Bentum-Puijk W, Bhimani Z, Bonten MJM, Bradbury CA, Brunkhorst FM, Burrell A, Buzgau A, Buxton M, Charles WN, Cove M, Detry MA, Estcourt LJ, Fagbodun EO, Fitzgerald M, Girard TD, Goligher EC, Goossens H, Haniffa R, Hills T, Horvat CM, Huang DT, Ichihara N, Lamontagne F, Marshall JC, McAuley DF, McGlothlin A, McGuinness SP, McVerry BJ, Neal MD, Nichol AD, Parke RL, Parker JC, Parry-Billings K, Peters SEC, Reyes LF, Rowan KM, Saito H, Santos MS, Saunders CT, Serpa-Neto A, Seymour CW, Shankar-Hari M, Stronach LM, Turgeon AF, Turner AM, van de Veerdonk FL, Zarychanski R, Green C, Lewis RJ, Angus DC, McArthur CJ, Berry S, Derde LPG, Gordon AC, Webb SA, Lawler PR. Writing Committee for the REMAP-CAP Investigators, et al. JAMA. 2023 Jan 3;329(1):39-51. doi: 10.1001/jama.2022.23257. JAMA. 2023. PMID: 36525245 Free PMC article.
IMPORTANCE: The longer-term effects of therapies for the treatment of critically ill patients with COVID-19 are unknown. OBJECTIVE: To determine the effect of multiple interventions for critically ill adults with COVID-19 on longer-term outcomes. DESIGN, SETTING, AN …
IMPORTANCE: The longer-term effects of therapies for the treatment of critically ill patients with COVID-19 are unknown. OBJECTIVE: T …
Haemoglobin transfusion threshold in traumatic brain injury optimisation (HEMOTION): a multicentre, randomised, clinical trial protocol.
Turgeon AF, Fergusson DA, Clayton L, Patton MP, Zarychanski R, English S, Docherty A, Walsh T, Griesdale D, Kramer AH, Scales D, Burns KEA, Boyd JG, Marshall JC, Kutsogiannis DJ, Ball I, Hébert PC, Lamontagne F, Costerousse O, St-Onge M, Lessard Bonaventure P, Moore L, Neveu X, Rigamonti A, Khwaja K, Green RS, Laroche V, Fox-Robichaud A, Lauzier F; HEMOTION Trial Team, the Canadian Critical Care Trials Group, the Canadian Perioperative Anesthesia Clinical Trials Group and the Canadian Traumatic Brain Injury Research Consortium. Turgeon AF, et al. Among authors: lauzier f. BMJ Open. 2022 Oct 10;12(10):e067117. doi: 10.1136/bmjopen-2022-067117. BMJ Open. 2022. PMID: 36216432 Free PMC article.
INTRODUCTION: Traumatic brain injury (TBI) is the leading cause of mortality and long-term disability in young adults. Despite the high prevalence of anaemia and red blood cell transfusion in patients with TBI, the optimal haemoglobin (Hb) transfusion threshold is unknown. …
INTRODUCTION: Traumatic brain injury (TBI) is the leading cause of mortality and long-term disability in young adults. Despite the hi …
Strategies to prevent long-term opioid use following trauma: a Canadian practice survey.
Bérubé M, Côté C, Moore L, Turgeon AF, Belzile ÉL, Richard-Denis A, Dale CM, Berry G, Choinière M, Pagé GM, Guénette L, Dupuis S, Tremblay L, Turcotte V, Martel MO, Chatillon CÉ, Perreault K, Lauzier F. Bérubé M, et al. Among authors: lauzier f. Can J Anaesth. 2023 Jan;70(1):87-99. doi: 10.1007/s12630-022-02328-8. Epub 2022 Sep 26. Can J Anaesth. 2023. PMID: 36163458 Free PMC article.
PURPOSE: To evaluate how Canadian clinicians involved in trauma patient care and prescribing opioids perceive the use and effectiveness of strategies to prevent long-term opioid therapy following trauma. Barriers and facilitators to the implementation of these strategies w …
PURPOSE: To evaluate how Canadian clinicians involved in trauma patient care and prescribing opioids perceive the use and effectiveness of s …
Near Infrared Spectroscopy for Poor Grade Aneurysmal Subarachnoid Hemorrhage-A Concise Review.
Francoeur CL, Lauzier F, Brassard P, Turgeon AF. Francoeur CL, et al. Among authors: lauzier f. Front Neurol. 2022 Apr 18;13:874393. doi: 10.3389/fneur.2022.874393. eCollection 2022. Front Neurol. 2022. PMID: 35518206 Free PMC article. Review.
An unreliable neurological exam and the lack of appropriate monitoring leads to unrecognized DCI, which in turn is associated with severe long-term deficits and higher mortality. Near Infrared Spectroscopy (NIRS) offers simple, continuous, real time, non-invasive cerebral …
An unreliable neurological exam and the lack of appropriate monitoring leads to unrecognized DCI, which in turn is associated with severe lo …
Strategies aimed at preventing long-term opioid use in trauma and orthopaedic surgery: a scoping review.
Côté C, Bérubé M, Moore L, Lauzier F, Tremblay L, Belzile E, Martel MO, Pagé G, Beaulieu Y, Pinard AM, Perreault K, Sirois C, Grzelak S, Turgeon AF. Côté C, et al. Among authors: lauzier f. BMC Musculoskelet Disord. 2022 Mar 11;23(1):238. doi: 10.1186/s12891-022-05044-y. BMC Musculoskelet Disord. 2022. PMID: 35277150 Free PMC article. Review.
BACKGROUND: Long-term opioid use, which may have significant individual and societal impacts, has been documented in up to 20% of patients after trauma or orthopaedic surgery. ...CONCLUSIONS: This scoping review advances knowledge on existing strategies to prevent long- …
BACKGROUND: Long-term opioid use, which may have significant individual and societal impacts, has been documented in up to 20% of pat …
Intensity of hospital resource use following traumatic brain injury: a multicentre cohort study, 2013-2016.
Assy C, Moore L, Porgo TV, Farhat I, Tardif PA, Truchon C, Stelfox HT, Gabbe BJ, Lauzier F, Turgeon AF, Clément J. Assy C, et al. Among authors: lauzier f. Can J Surg. 2022 Mar 2;65(2):E143-E153. doi: 10.1503/cjs.007819. Print 2022 Mar-Apr. Can J Surg. 2022. PMID: 35236668 Free PMC article.
We observed significant interhospital variation in resource use for patients discharged alive, which was not explained by patient case mix (ICC 0.052, 95% CI 0.043 to 0.061). Adjusted mean resource use for patients discharged to long-term care was more than twice that of p …
We observed significant interhospital variation in resource use for patients discharged alive, which was not explained by patient case mix ( …
Tapering Opioid Prescription Program for High-Risk Trauma Patients: A Pilot Randomized Controlled Trial.
Bérubé M, Dupuis S, Leduc S, Roy I, Turcotte V, Côté C, Grzelak S, Clairoux S, Panic S, Lauzier F. Bérubé M, et al. Among authors: lauzier f. Pain Manag Nurs. 2022 Apr;23(2):142-150. doi: 10.1016/j.pmn.2021.08.001. Epub 2021 Aug 31. Pain Manag Nurs. 2022. PMID: 34479822 Clinical Trial.
AIMS: To assess the feasibility and acceptability of TOPP-Trauma, examine the feasibility of the research methods, and describe its potential efficacy in reducing long-term opioid use. DESIGN: A two-arm pilot randomized controlled trial. ...
AIMS: To assess the feasibility and acceptability of TOPP-Trauma, examine the feasibility of the research methods, and describe its potentia …
23 results