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Ceftriaxone to prevent early ventilator-associated pneumonia in patients with acute brain injury: a multicentre, randomised, double-blind, placebo-controlled, assessor-masked superiority trial.
Dahyot-Fizelier C, Lasocki S, Kerforne T, Perrigault PF, Geeraerts T, Asehnoune K, Cinotti R, Launey Y, Cottenceau V, Laffon M, Gaillard T, Boisson M, Aleyrat C, Frasca D, Mimoz O; PROPHY-VAP Study Group and the ATLANREA Study Group. Dahyot-Fizelier C, et al. Among authors: lasocki s. Lancet Respir Med. 2024 May;12(5):375-385. doi: 10.1016/S2213-2600(23)00471-X. Epub 2024 Jan 20. Lancet Respir Med. 2024. PMID: 38262428 Clinical Trial.
BACKGROUND: Patients with acute brain injury are at high risk of ventilator-associated pneumonia (VAP). The benefit of short-term antibiotic prophylaxis remains debated. We aimed to establish the effect of an early, single dose of the antibiotic ceftriaxone on the incidenc …
BACKGROUND: Patients with acute brain injury are at high risk of ventilator-associated pneumonia (VAP). The benefit of short-term ant …
Skin antisepsis with chlorhexidine-alcohol versus povidone iodine-alcohol, with and without skin scrubbing, for prevention of intravascular-catheter-related infection (CLEAN): an open-label, multicentre, randomised, controlled, two-by-two factorial trial.
Mimoz O, Lucet JC, Kerforne T, Pascal J, Souweine B, Goudet V, Mercat A, Bouadma L, Lasocki S, Alfandari S, Friggeri A, Wallet F, Allou N, Ruckly S, Balayn D, Lepape A, Timsit JF; CLEAN trial investigators. Mimoz O, et al. Among authors: lasocki s. Lancet. 2015 Nov 21;386(10008):2069-2077. doi: 10.1016/S0140-6736(15)00244-5. Epub 2015 Sep 18. Lancet. 2015. PMID: 26388532 Clinical Trial.
Optimisation of skin antisepsis is essential to prevent short-term catheter-related infections. We hypothesised that chlorhexidine-alcohol would be more effective than povidone iodine-alcohol as a skin antiseptic to prevent intravascular-catheter-related infections. ...INT …
Optimisation of skin antisepsis is essential to prevent short-term catheter-related infections. We hypothesised that chlorhexidine-al …
EPIdemiology of Surgery-Associated Acute Kidney Injury (EPIS-AKI): study protocol for a multicentre, observational trial.
Weiss R, Saadat-Gilani K, Kerschke L, Wempe C, Meersch M, Zarbock A; EPIS-AKI Investigators. Weiss R, et al. BMJ Open. 2021 Dec 30;11(12):e055705. doi: 10.1136/bmjopen-2021-055705. BMJ Open. 2021. PMID: 35588372 Free PMC article.
Acute kidney injury (AKI) is a common complication after major surgery and is associated with adverse short-term and long-term outcomes. However, there is a large variation in the incidence of reported AKI rates. ...
Acute kidney injury (AKI) is a common complication after major surgery and is associated with adverse short-term and long-term …
Long-Term Outcome of Severe Metabolic Acidemia in ICU Patients, a BICAR-ICU Trial Post Hoc Analysis.
Bendiab E, Garnier F, Soler M, Fosset M, Jaber S, Molinari N, Jung B; BICAR-ICU Investigators. Bendiab E, et al. Crit Care Med. 2023 Jan 1;51(1):e1-e12. doi: 10.1097/CCM.0000000000005706. Epub 2022 Nov 8. Crit Care Med. 2023. PMID: 36351174 Clinical Trial.
OBJECTIVES: Long-term prognosis of ICU survivors is a major issue. Severe acidemia upon ICU admission is associated with very high short-term mortality. Since the long-term prognosis of these patients is unknown, we aimed to determine the long-term hea …
OBJECTIVES: Long-term prognosis of ICU survivors is a major issue. Severe acidemia upon ICU admission is associated with very high sh …
Anxiety and depression symptoms in relatives of moderate-to-severe traumatic brain injury survivors - A multicentre cohort.
Cinotti R, Chopin A, Moyer JD, Huet O, Lasocki S, Cohen B, Dahyot-Fizelier C, Chalard K, Seguin P, Martin FP, Lerebourg C, Guitteny M, Chenet A, Perrouin-Verbe B, Asehnoune K, Feuillet F, Sébille V, Roquilly A; Atlanréa Group and the Société Française d’Anesthésie-Réanimation–SFAR Research Network. Cinotti R, et al. Among authors: lasocki s. Anaesth Crit Care Pain Med. 2023 Oct;42(5):101232. doi: 10.1016/j.accpm.2023.101232. Epub 2023 Apr 11. Anaesth Crit Care Pain Med. 2023. PMID: 37054915 Clinical Trial.
Anxiety and depression were inversely correlated with the patient's mental health status at 6 months. CONCLUSIONS: Long-term follow-up must provide psychological care to relatives after TBI....
Anxiety and depression were inversely correlated with the patient's mental health status at 6 months. CONCLUSIONS: Long-term follow-u …
Dexmedetomidine after Cardiac Surgery for Prevention of Delirium (EXACTUM) trial protocol: a multicentre randomised, double-blind, placebo-controlled trial.
Gargadennec T, Oilleau JF, Rozec B, Nesseler N, Lasocki S, Futier E, Amour J, Durand M, Bougle A, Kerforne T, Consigny M, Eddi D, Huet O. Gargadennec T, et al. Among authors: lasocki s. BMJ Open. 2022 Apr 8;12(4):e058968. doi: 10.1136/bmjopen-2021-058968. BMJ Open. 2022. PMID: 35396310 Free PMC article.
INTRODUCTION: Incidence of delirium after cardiac surgery remains high and delirium has a significant burden on short-term and long-term outcomes. Multiple causes can trigger delirium occurence, and it has been hypothesised that sleep disturbances can be one of them …
INTRODUCTION: Incidence of delirium after cardiac surgery remains high and delirium has a significant burden on short-term and long- …
[The use of cardiac troponins (T or I) measurement in cardiology and various clinical settings].
Berroëta C, Provenchère S, Mongredien A, Lasocki S, Benessiano J, Dehoux M, Philip I. Berroëta C, et al. Among authors: lasocki s. Ann Fr Anesth Reanim. 2006 Oct;25(10):1053-63. doi: 10.1016/j.annfar.2005.05.017. Epub 2005 Jul 12. Ann Fr Anesth Reanim. 2006. PMID: 16019183 Review. French.
Recent studies suggest that any elevation of troponin in the postoperative period is indicative of increased risk of long-term cardiac complications. This prognostic value has been previously demonstrated in other clinical settings such as invasive coronary intervention (s …
Recent studies suggest that any elevation of troponin in the postoperative period is indicative of increased risk of long-term cardia …
Association between in-ICU red blood cells transfusion and 1-year mortality in ICU survivors.
Blet A, McNeil JB, Josse J, Cholley B, Cinotti R, Cotter G, Dauvergne A, Davison B, Duarte K, Duranteau J, Fournier MC, Gayat E, Jaber S, Lasocki S, Merkling T, Peoc'h K, Mayer I, Sadoune M, Laterre PF, Sonneville R, Ware L, Mebazaa A, Kimmoun A. Blet A, et al. Among authors: lasocki s. Crit Care. 2022 Oct 7;26(1):307. doi: 10.1186/s13054-022-04171-1. Crit Care. 2022. PMID: 36207737 Free PMC article.
BACKGROUND: Impact of in-ICU transfusion on long-term outcomes remains unknown. The purpose of this study was to assess in critical-care survivors the association between in-ICU red blood cells transfusion and 1-year mortality. ...Weighted analyses including 40 confounders …
BACKGROUND: Impact of in-ICU transfusion on long-term outcomes remains unknown. The purpose of this study was to assess in critical-c …
Validation of the postoperative Quality of Recovery-15 questionnaire after emergency surgery and association with quality of life at three months.
Le Bescond V, Petit-Phan J, Campfort M, Nicolleau C, Conté M, Bouhours G, Rony L, Lasocki S, Léger M. Le Bescond V, et al. Among authors: lasocki s. Can J Anaesth. 2024 May;71(5):590-599. doi: 10.1007/s12630-024-02722-4. Epub 2024 Mar 19. Can J Anaesth. 2024. PMID: 38504036 Free PMC article.
PURPOSE: The Quality of Recovery-15 (QoR-15) tool, validated for measuring postoperative recovery following scheduled surgeries, has not been psychometrically assessed in emergency contexts. Moreover, the QoR-15's associations with long-term outcomes remain underexplored. …
PURPOSE: The Quality of Recovery-15 (QoR-15) tool, validated for measuring postoperative recovery following scheduled surgeries, has not bee …
A long-term clinical evaluation of autoflow during assist-controlled ventilation: a randomized controlled trial.
Lasocki S, Labat F, Plantefeve G, Desmard M, Mentec H. Lasocki S, et al. Anesth Analg. 2010 Oct;111(4):915-21. doi: 10.1213/ANE.0b013e3181f00015. Epub 2010 Aug 12. Anesth Analg. 2010. PMID: 20705780 Clinical Trial.
"Dual-controlled" modes, such as AutoFlow, are supposed to improve patient- ventilator interfacing and could lead to fewer alarms. We performed a long-term clinical evaluation of the efficacy and safety of AutoFlow during assist-controlled ventilation, focusing on ventilat …
"Dual-controlled" modes, such as AutoFlow, are supposed to improve patient- ventilator interfacing and could lead to fewer alarms. We perfor …
16 results