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Increased mitochondrial Ca2+ and decreased sarcoplasmic reticulum Ca2+ in mitochondrial myopathy.
Aydin J, Andersson DC, Hänninen SL, Wredenberg A, Tavi P, Park CB, Larsson NG, Bruton JD, Westerblad H. Aydin J, et al. Among authors: larsson ng. Hum Mol Genet. 2009 Jan 15;18(2):278-88. doi: 10.1093/hmg/ddn355. Epub 2008 Oct 22. Hum Mol Genet. 2009. PMID: 18945718
In conclusion, we suggest that the observed changes in Ca(2+) handling are adaptive responses with long-term detrimental effects. Reduced SR Ca(2+) release likely decreases ATP expenditure, but it also induces muscle weakness. ...
In conclusion, we suggest that the observed changes in Ca(2+) handling are adaptive responses with long-term detrimental effects. Red …
Lack of transmission of deleted mtDNA from a woman with Kearns-Sayre syndrome to her child.
Larsson NG, Eiken HG, Boman H, Holme E, Oldfors A, Tulinius MH. Larsson NG, et al. Am J Hum Genet. 1992 Feb;50(2):360-3. Am J Hum Genet. 1992. PMID: 1734716 Free PMC article.
No deleted mtDNA was detected in blood from the mother of the patient. The patient had an uneventful pregnancy and delivered at term. Deleted mtDNA could not be detected in placenta by Southern blot analysis. ...
No deleted mtDNA was detected in blood from the mother of the patient. The patient had an uneventful pregnancy and delivered at term. …