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Outcomes and Complications of Limbal Stem Cell Allograft Transplantation: A Report by the American Academy of Ophthalmology.
Li JY, Cortina MS, Greiner MA, Kuo AN, Miller DD, Shtein RM, Veldman PB, Yin J, Kim SJ, Shen JF. Li JY, et al. Among authors: kuo an. Ophthalmology. 2024 Apr 27:S0161-6420(24)00157-X. doi: 10.1016/j.ophtha.2024.02.018. Online ahead of print. Ophthalmology. 2024. PMID: 38678469
However, the level and duration of immunosuppression vary widely between the studies and may impact allograft rejections and long-term graft survival. Complications related to immunosuppression are minimal. Repeat surgery may be needed to maintain a viable ocular surface. …
However, the level and duration of immunosuppression vary widely between the studies and may impact allograft rejections and long-term …
Augmentation of Endothelial S1PR1 Attenuates Postviral Pulmonary Fibrosis.
Brazee PL, Cartier A, Kuo A, Haring AM, Nguyen T, Hariri LP, Griffith JW, Hla T, Medoff BD, Knipe RS. Brazee PL, et al. Among authors: kuo a. Am J Respir Cell Mol Biol. 2024 Feb;70(2):119-128. doi: 10.1165/rcmb.2023-0286OC. Am J Respir Cell Mol Biol. 2024. PMID: 37934676
Here, we used a clinically relevant influenza A virus infection model, endothelial cell-specific transgenic gain-of-function and loss-of-function mice as well as pharmacologic approaches and in vitro modeling, to define the mechanism by which S1PR1 expression is dampened during i …
Here, we used a clinically relevant influenza A virus infection model, endothelial cell-specific transgenic gain-of-function and loss-of-fun …
Comparative genomics of Mollicutes-related endobacteria supports a late invasion into Mucoromycota fungi.
Longley R, Robinson A, Liber JA, Bryson AE, Morales DP, LaButti K, Riley R, Mondo SJ, Kuo A, Yoshinaga Y, Daum C, Barry K, Grigoriev IV, Desirò A, Chain PSG, Bonito G. Longley R, et al. Among authors: kuo a. Commun Biol. 2023 Sep 18;6(1):948. doi: 10.1038/s42003-023-05299-8. Commun Biol. 2023. PMID: 37723238 Free PMC article.
We posit that reductions in genome size, GC content, pseudogene content, and repeat content in MRE-L may reflect a longer-term relationship with their fungal hosts. These data indicate Linnemannia and Benniella MRE were likely acquired independently after their fungal host …
We posit that reductions in genome size, GC content, pseudogene content, and repeat content in MRE-L may reflect a longer-term relati …
Eight-Year Outcomes of Bilateral Lateral Rectus Recessions versus Unilateral Recession-Resection in Childhood Basic-Type Intermittent Exotropia.
Donahue SP, Chandler DL, Wu R, Marsh JD, Law C, Areaux RG Jr, Ghasia FF, Li Z, Kraker RT, Cotter SA, Holmes JM; Pediatric Eye Disease Investigator Group. Donahue SP, et al. Ophthalmology. 2024 Jan;131(1):98-106. doi: 10.1016/j.ophtha.2023.09.004. Epub 2023 Sep 9. Ophthalmology. 2024. PMID: 37696452 Clinical Trial.
CONCLUSIONS: Despite no significant difference for the primary outcome, the 95% CI did not exclude a moderate benefit of R&R, which together with secondary outcomes suggests that unilateral R&R followed by usual care may yield better long-term outcomes than BLRc fo …
CONCLUSIONS: Despite no significant difference for the primary outcome, the 95% CI did not exclude a moderate benefit of R&R, which toge …
Management of immune-related cutaneous adverse events with dupilumab.
Kuo AM, Gu S, Stoll J, Moy AP, Dusza SW, Gordon A, Haliasos EC, Janjigian Y, Kraehenbuehl L, Quigley EA, Chapman P, Lacouture ME, Markova A. Kuo AM, et al. J Immunother Cancer. 2023 Jun;11(6):e007324. doi: 10.1136/jitc-2023-007324. J Immunother Cancer. 2023. PMID: 37270183 Free PMC article.
Nonetheless, prospective, randomized, controlled trials are warranted to confirm these observations and confirm its long-term safety....
Nonetheless, prospective, randomized, controlled trials are warranted to confirm these observations and confirm its long-term safety. …
Genomic determination of breeding systems and trans-specific evolution of HD MAT genes in suilloid fungi.
Ke YH, Branco S, Bazzicalupo AL, Nguyen NH, Liao HL, Kennedy P, Bruns TD, Kuo A, LaButti K, Barry K, Grigoriev I, Vilgalys R. Ke YH, et al. Among authors: kuo a. Genetics. 2023 May 26;224(2):iyad069. doi: 10.1093/genetics/iyad069. Genetics. 2023. PMID: 37070772 Free PMC article.
High sequence divergence, trans-specific polymorphism, and the deeply diverging genealogy confirm the long-term functionality and multiallelic status of HD MAT locus in suilloid fungi. ...
High sequence divergence, trans-specific polymorphism, and the deeply diverging genealogy confirm the long-term functionality and mul …
A Tool to Estimate Risk of 30-day Mortality and Complications After Hip Fracture Surgery: Accurate Enough for Some but Not All Purposes? A Study From the ACS-NSQIP Database.
Harris AHS, Trickey AW, Eddington HS, Seib CD, Kamal RN, Kuo AC, Ding Q, Giori NJ. Harris AHS, et al. Among authors: kuo ac. Clin Orthop Relat Res. 2022 Dec 1;480(12):2335-2346. doi: 10.1097/CORR.0000000000002294. Epub 2022 Jun 27. Clin Orthop Relat Res. 2022. PMID: 35901441 Free PMC article.
BACKGROUND: Surgical repair of hip fracture carries substantial short-term risks of mortality and complications. The risk-reward calculus for most patients with hip fractures favors surgical repair. ...
BACKGROUND: Surgical repair of hip fracture carries substantial short-term risks of mortality and complications. The risk-reward calc …
Salinity tolerance mechanisms of an Arctic Pelagophyte using comparative transcriptomic and gene expression analysis.
Freyria NJ, Kuo A, Chovatia M, Johnson J, Lipzen A, Barry KW, Grigoriev IV, Lovejoy C. Freyria NJ, et al. Among authors: kuo a. Commun Biol. 2022 May 25;5(1):500. doi: 10.1038/s42003-022-03461-2. Commun Biol. 2022. PMID: 35614207 Free PMC article.
Little is known at the transcriptional level about microbial eukaryotic adaptations to short-term salinity change. Arctic microalgae are exposed to low salinity due to sea-ice melt and higher salinity with brine channel formation during freeze-up. ...
Little is known at the transcriptional level about microbial eukaryotic adaptations to short-term salinity change. Arctic microalgae …
Maternal and Child Health Pipeline Training Programs: A Description of Training Across 6 Funded Programs.
Moerchen V, Taylor-DeOliveira L, Dietrich M, Armstrong A, Azeredo J, Belcher H, Copeland-Linder N, Fernandes P, Kuo A, Noble C, Olaleye O, Salihu H, Waters CR, Brown C, Reddy MM. Moerchen V, et al. Among authors: kuo a. Matern Child Health J. 2022 Aug;26(Suppl 1):137-146. doi: 10.1007/s10995-022-03375-9. Epub 2022 Mar 14. Matern Child Health J. 2022. PMID: 35286520 Free PMC article.
Finally, the link to Maternal and Child Health Bureau (MCHB) long-term training and other MCHB opportunities for professional development contributed significant nuance to the pipeline-to-workforce objectives of these programs. ...
Finally, the link to Maternal and Child Health Bureau (MCHB) long-term training and other MCHB opportunities for professional develop …
LEFTY1 Is a Dual-SMAD Inhibitor that Promotes Mammary Progenitor Growth and Tumorigenesis.
Zabala M, Lobo NA, Antony J, Heitink LS, Gulati GS, Lam J, Parashurama N, Sanchez K, Adorno M, Sikandar SS, Kuo AH, Qian D, Kalisky T, Sim S, Li L, Dirbas FM, Somlo G, Newman A, Quake SR, Clarke MF. Zabala M, et al. Among authors: kuo ah. Cell Stem Cell. 2020 Aug 6;27(2):284-299.e8. doi: 10.1016/j.stem.2020.06.017. Epub 2020 Jul 20. Cell Stem Cell. 2020. PMID: 32693087 Free article.
Here, we show that LEFTY1, a secreted inhibitor of NODAL/SMAD2 signaling, is produced by mammary progenitor cells and, concomitantly, suppresses SMAD2 and SMAD5 signaling to promote long-term proliferation of normal and malignant mammary epithelial cells. ...
Here, we show that LEFTY1, a secreted inhibitor of NODAL/SMAD2 signaling, is produced by mammary progenitor cells and, concomitantly, suppre …
29 results