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Involved-field radiotherapy in older patients with superficial thoracic esophageal squamous cell carcinoma: long-term outcomes and recurrence patterns.
Kono S, Hashimoto Y, Ohmatsu K, Tsujii M, Kuribayashi S, Karasawa K. Kono S, et al. Jpn J Radiol. 2024 Apr 22. doi: 10.1007/s11604-024-01564-w. Online ahead of print. Jpn J Radiol. 2024. PMID: 38647885
PURPOSE: An optimal radiotherapy field for superficial esophageal carcinoma is yet to be established. We evaluated the long-term outcomes and recurrence patterns of involved-field radiotherapy (IFRT) in older patients with superficial thoracic esophageal squamous cell carc …
PURPOSE: An optimal radiotherapy field for superficial esophageal carcinoma is yet to be established. We evaluated the long-term outc …
Factors associated with long-term efficacy of lubiprostone for chronic constipation.
Morise T, Fukuzawa M, Sugimoto M, Nagata N, Kono S, Yamauchi Y, Sugimoto A, Uchida K, Koyama Y, Madarame A, Yamaguchi H, Matsumoto T, Kagawa Y, Kawai T, Itoi T. Morise T, et al. Among authors: kono s. J Clin Biochem Nutr. 2023 Jul;73(1):91-96. doi: 10.3164/jcbn.22-24. Epub 2023 May 16. J Clin Biochem Nutr. 2023. PMID: 37534090 Free PMC article.
Although the chloride channel activator lubiprostone is candidate drug that may solve these problems, factors associated with the long-term efficacy of lubiprostone monotherapy for chronic constipation in treatment-naive patients remain unclear. We here retrospectively inv …
Although the chloride channel activator lubiprostone is candidate drug that may solve these problems, factors associated with the long-te
A long-term survival case of bladder cancer with distant metastases: abscopal effect of brain metastases after stereotactic radiotherapy with immune checkpoint blockade therapy to lung metastases.
Kono S, Hashimoto Y, Shirai Y, Kunihiro Y, Ohmatsu K, Kawanishi M, Kuribayashi S, Karasawa K. Kono S, et al. Int Cancer Conf J. 2023 Apr 3;12(3):205-209. doi: 10.1007/s13691-023-00606-w. eCollection 2023 Jul. Int Cancer Conf J. 2023. PMID: 37251008 Free PMC article.
We report a case of abscopal effect in a single brain metastasis from bladder cancer in a patient treated with focal stereotactic radiotherapy (total dose = 52 Gy, administered in eight fractions) with immune checkpoint blockade therapy for lung metastases, who achieved long-t
We report a case of abscopal effect in a single brain metastasis from bladder cancer in a patient treated with focal stereotactic radiothera …
Significance of Hypofractionated Radiotherapy in Postoperative Irradiation for Breast Cancer: An Asian Multi-institutional Prospective Study.
Okonogi N, Kono S, Karasawa K, Banu PA, Xu X, Erawati D, Adylkhanov T, Jang WI, E Y, Calaguas MJ, Thephamongkhol K, Dung TA, Ng WNP, Kato S; Forum for Nuclear Cooperation in Asia. Okonogi N, et al. Among authors: kono s. Clin Oncol (R Coll Radiol). 2023 Jul;35(7):463-471. doi: 10.1016/j.clon.2023.04.007. Epub 2023 May 3. Clin Oncol (R Coll Radiol). 2023. PMID: 37179216 Free article.
Hypofractionated WBI and hypofractionated PMRT are reasonable approaches that can contain cancer care costs in these countries. Long-term observation is required to validate our findings....
Hypofractionated WBI and hypofractionated PMRT are reasonable approaches that can contain cancer care costs in these countries. Long-term
Abscopal complete regression of hepatocellular carcinoma with multiple pleural metastases.
Ohmatsu K, Hashimoto Y, Kawanishi M, Ishii Y, Kono S, Kuribayashi S, Ariizumi S, Karasawa K. Ohmatsu K, et al. Among authors: kono s. Int Cancer Conf J. 2020 Sep 25;10(1):54-58. doi: 10.1007/s13691-020-00446-y. eCollection 2021 Jan. Int Cancer Conf J. 2020. PMID: 33489702 Free PMC article.
We report a case of abscopal effect in HCC with multiple pleural metastases in a patient who was treated with focal radiotherapy to extrahepatic metastasis, and achieved long-term survival. We performed radiotherapy only to the tumor in inferior vena cava and the proximal …
We report a case of abscopal effect in HCC with multiple pleural metastases in a patient who was treated with focal radiotherapy to extrahep …
Peroral endoscopic myotomy and fundoplication: a novel NOTES procedure.
Inoue H, Ueno A, Shimamura Y, Manolakis A, Sharma A, Kono S, Nishimoto M, Sumi K, Ikeda H, Goda K, Onimaru M, Yamaguchi N, Itoh H. Inoue H, et al. Among authors: kono s. Endoscopy. 2019 Feb;51(2):161-164. doi: 10.1055/a-0820-2731. Epub 2019 Jan 17. Endoscopy. 2019. PMID: 30654395
A pilot study was conducted in which an endoscopic fundoplication was added to the standard POEM (POEM + F) procedure to overcome this issue. We report the technical details of POEM + F and short-term safety results. METHODS: POEM + F was performed in 21 patients. ...
A pilot study was conducted in which an endoscopic fundoplication was added to the standard POEM (POEM + F) procedure to overcome this issue …
The 5-year outcomes of moderately hypofractionated radiotherapy (66 Gy in 22 fractions, 3 fractions per week) for localized prostate cancer: a retrospective study.
Hashimoto Y, Motegi A, Akimoto T, Mitsuhashi N, Iizuka J, Tanabe K, Ishii Y, Kono S, Izumi S, Karasawa K. Hashimoto Y, et al. Among authors: kono s. Int J Clin Oncol. 2018 Feb;23(1):165-172. doi: 10.1007/s10147-017-1175-1. Epub 2017 Jul 31. Int J Clin Oncol. 2018. PMID: 28758177 Clinical Trial.
CONCLUSIONS: The moderately hypofractionated radiotherapy protocol yielded short-term satisfactory clinical outcomes with acceptable toxicity....
CONCLUSIONS: The moderately hypofractionated radiotherapy protocol yielded short-term satisfactory clinical outcomes with acceptable …
Efficacy and Safety of Long-term Coadministration of Fenofibrate and Ezetimibe in Patients with Combined Hyperlipidemia: Results of the EFECTL Study.
Oikawa S, Yamashita S, Nakaya N, Sasaki J, Kono S; Effect of Fenofibrate and Ezetimibe Combination Treatment on Lipid (EFECTL) Study Investigators. Oikawa S, et al. Among authors: kono s. J Atheroscler Thromb. 2017 Jan 1;24(1):77-94. doi: 10.5551/jat.35626. Epub 2016 Jul 8. J Atheroscler Thromb. 2017. PMID: 27397061 Free PMC article. Clinical Trial.
AIM: We investigated the safety and efficacy of a long-term combination therapy with fenofibrate and ezetimibe in Japanese patients with combined hyperlipidemia, in comparison with fenofibrate or ezetimibe alone. ...CONCLUSION: The combination therapy with fenofibrate and …
AIM: We investigated the safety and efficacy of a long-term combination therapy with fenofibrate and ezetimibe in Japanese patients w …
Morphologic and Histologic Changes in Gastric Adenomas After Helicobacter pylori Eradication: A Long-Term Prospective Analysis.
Suzuki S, Gotoda T, Suzuki H, Kono S, Iwatsuka K, Kusano C, Oda I, Sekine S, Moriyasu F. Suzuki S, et al. Among authors: kono s. Helicobacter. 2015 Dec;20(6):431-7. doi: 10.1111/hel.12218. Epub 2015 Feb 23. Helicobacter. 2015. PMID: 25704290
The effect of H. pylori eradication on pre-existing gastric neoplasias is still controversial. The aim of this study was to use long-term observation to clarify morphologic and histologic changes in gastric adenomas following H. pylori eradication. ...
The effect of H. pylori eradication on pre-existing gastric neoplasias is still controversial. The aim of this study was to use long-term
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