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[Participation in children's hospitals: approaches to participatory formats for paediatric patients].
Bauer J, Clark H, Coenen M, Klein C, Rehfuess EA, Ruther C, Voss S, Voigt-Blaurock V, Jung-Sievers C. Bauer J, et al. Among authors: klein c. Gesundheitswesen. 2024 Apr 23. doi: 10.1055/a-2270-2840. Online ahead of print. Gesundheitswesen. 2024. PMID: 38653470 German.
These formats must be chosen in such a way that they can realistically be implemented in clinical settings as well as in pediatric research, and that they can be sustained in the long term. In order to strengthen the consideration of children's rights in the health system, …
These formats must be chosen in such a way that they can realistically be implemented in clinical settings as well as in pediatric research, …
CD19-CD28: An affinity-optimized CD28 agonist for combination with glofitamab (CD20-TCB) as off-the-shelf immunotherapy.
Sam J, Hofer T, Kuettel C, Claus C, Thom J, Herter S, Georges G, Korfi K, Lechmann M, Eigenmann MJ, Marbach D, Jamois C, Lechner K, Krishnan SM, Gaillard BC, Marinho J, Kronenberg S, Kunz L, Wilson S, Briner S, Gebhardt S, Varol A, Appelt B, Nicolini VG, Speziale D, Bez M, Bommer E, Eckmann J, Hage C, Limani F, Jenni S, Schoenle A, Le Clech M, Vallier JB, Colombetti S, Bacac M, Gasser S, Klein C, Umaña P. Sam J, et al. Among authors: klein c. Blood. 2024 Mar 4:blood.2023023381. doi: 10.1182/blood.2023023381. Online ahead of print. Blood. 2024. PMID: 38437725 Free article.
Notably, the triple combination of glofitamab with CD19-CD28 with the costimulatory 4-1BB agonist CD19-4-1BBL, offered substantially improved long-term tumor control over glofitamab monotherapy and respective duplet combinations. ...
Notably, the triple combination of glofitamab with CD19-CD28 with the costimulatory 4-1BB agonist CD19-4-1BBL, offered substantially improve …
Nitrogen loading resulting from major floods and sediment resuspension to a large coastal embayment.
Grinham A, Costantini T, Deering N, Jackson C, Klein C, Lovelock C, Pandolfi J, Eyal G, Linde M, Dunbabin M, Duncan B, Hutley N, Byrne I, Wilson C, Albert S. Grinham A, et al. Among authors: klein c. Sci Total Environ. 2024 Mar 25;918:170646. doi: 10.1016/j.scitotenv.2024.170646. Epub 2024 Feb 5. Sci Total Environ. 2024. PMID: 38325481 Free article.
Short-term impacts were assessed three days after the flood peak by sampling surface water at 47 sites in the direction of the predominant circulation pattern. Longer-term impacts were assessed by undertaking an intensive sediment survey of 223 sites and a nutrient …
Short-term impacts were assessed three days after the flood peak by sampling surface water at 47 sites in the direction of the predom …
Receptor-Independent Therapies for Forensic Detainees with Schizophrenia-Dementia Comorbidity.
Sfera A, Andronescu L, Britt WG, Himsl K, Klein C, Rahman L, Kozlakidis Z. Sfera A, et al. Among authors: klein c. Int J Mol Sci. 2023 Oct 31;24(21):15797. doi: 10.3390/ijms242115797. Int J Mol Sci. 2023. PMID: 37958780 Free PMC article.
Moreover, as antipsychotic drugs became available in 1950s and 1960s, we are observing the first generation of forensic detainees who have aged on dopamine-blocking agents. Although the consequences of long-term treatment with these agents are unclear, schizophrenia-associ …
Moreover, as antipsychotic drugs became available in 1950s and 1960s, we are observing the first generation of forensic detainees who have a …
[Oncological and functional results of focal treatment of localized prostate cancer with HIFU].
Debard C, Margue G, Klein C, Rompré-Brodeur A, Marcq G, Bensadoun H, Robert G, Anidjar M, Bladou F. Debard C, et al. Among authors: klein c. Prog Urol. 2023 Dec;33(15-16):966-973. doi: 10.1016/j.purol.2023.09.012. Epub 2023 Sep 26. Prog Urol. 2023. PMID: 37770359 French.
INTRODUCTION: In recent years, improved diagnosis of prostate cancer has allowed the development of focal therapy, in order to reduce the morbidity of treatments. Our study assesses the medium-term oncological and functional results of FocalOne HIFU treatment in localized …
INTRODUCTION: In recent years, improved diagnosis of prostate cancer has allowed the development of focal therapy, in order to reduce the mo …
THC-O-Acetate: Scarce Evidence for a Psychedelic Cannabinoid.
Kruger DJ, Bone CC, Meacham MC, Klein C, Kruger JS. Kruger DJ, et al. Among authors: klein c. J Psychoactive Drugs. 2023 Jun 29:1-5. doi: 10.1080/02791072.2023.2230573. Online ahead of print. J Psychoactive Drugs. 2023. PMID: 37381980
Participants reported a low to moderate level of cognitive distortions (altered sense of time, difficulties concentrating, difficulties with short-term memory) and few visuals or hallucinations. Participants' responses were significantly below the threshold for a complete …
Participants reported a low to moderate level of cognitive distortions (altered sense of time, difficulties concentrating, difficulties with …
Genetic Testing in Parkinson's Disease.
Pal G, Cook L, Schulze J, Verbrugge J, Alcalay RN, Merello M, Sue CM, Bardien S, Bonifati V, Chung SJ, Foroud T, Gatto E, Hall A, Hattori N, Lynch T, Marder K, Mascalzoni D, Novaković I, Thaler A, Raymond D, Salari M, Shalash A, Suchowersky O, Mencacci NE, Simuni T, Saunders-Pullman R, Klein C. Pal G, et al. Among authors: klein c. Mov Disord. 2023 Aug;38(8):1384-1396. doi: 10.1002/mds.29500. Epub 2023 Jun 27. Mov Disord. 2023. PMID: 37365908 Free PMC article.
(2) How, if at all, should testing vary based on ethnicity? (3) What are the long-term outcomes of consumer- and research-based genetic testing in presymptomatic PD? ...
(2) How, if at all, should testing vary based on ethnicity? (3) What are the long-term outcomes of consumer- and research-based genet …
Bispecific antibodies redirect synthetic agonistic receptor modified T cells against melanoma.
Märkl F, Benmebarek MR, Keyl J, Cadilha BL, Geiger M, Karches C, Obeck H, Schwerdtfeger M, Michaelides S, Briukhovetska D, Stock S, Jobst J, Müller PJ, Majed L, Seifert M, Klüver AK, Lorenzini T, Grünmeier R, Thomas M, Gottschlich A, Klaus R, Marr C, von Bergwelt-Baildon M, Rothenfusser S, Levesque MP, Heppt MV, Endres S, Klein C, Kobold S. Märkl F, et al. Among authors: klein c. J Immunother Cancer. 2023 May;11(5):e006436. doi: 10.1136/jitc-2022-006436. J Immunother Cancer. 2023. PMID: 37208128 Free PMC article.
The presence of target cells and anti-TYRP1 anti-SAR or anti-MCSP anti-SAR BiAb induced conditional antigen-dependent activation, proliferation of SAR T cells and targeted tumor cell lysis in all tested models. In vivo, antitumoral activity and long-term survival was media …
The presence of target cells and anti-TYRP1 anti-SAR or anti-MCSP anti-SAR BiAb induced conditional antigen-dependent activation, proliferat …
Influence of key factors on ammonia and nitrous oxide emission factors for excreta deposited by livestock and land-applied manure.
van der Weerden TJ, Noble AN, Beltran I, Hutchings NJ, Thorman RE, de Klein CAM, Amon B. van der Weerden TJ, et al. Among authors: de klein cam. Sci Total Environ. 2023 Sep 1;889:164066. doi: 10.1016/j.scitotenv.2023.164066. Epub 2023 May 17. Sci Total Environ. 2023. PMID: 37201844 Free article.
Total variability explained by terms in mixed effect model was on average 66 %, with the random effect 'experiment identification number' explaining, on average, 41 % of the total variability in the models. We suspect this term captured the effect of non-measured manure, s …
Total variability explained by terms in mixed effect model was on average 66 %, with the random effect 'experiment identification number' ex …
Knee laxity after anterior tibial eminence fracture in children: A 35-case series.
Arroume A, Pascual M, Mathieu F, Deroussen F, Gouron R, Klein C. Arroume A, et al. Among authors: klein c. Orthop Traumatol Surg Res. 2023 Dec;109(8):103533. doi: 10.1016/j.otsr.2022.103533. Epub 2022 Dec 23. Orthop Traumatol Surg Res. 2023. PMID: 36572379
INTRODUCTION: Anterior tibial eminence (ATE) fractures are characterized by avulsion of the anterior cruciate ligament insertion. The aim of our study was to evaluate the long-term incidence of laxity and instability in the aftermath of these fractures. ...DISCUSSION: Our …
INTRODUCTION: Anterior tibial eminence (ATE) fractures are characterized by avulsion of the anterior cruciate ligament insertion. The aim of …
197 results