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Pharmacotherapy for obesity: recent evolution and implications for cardiovascular risk reduction.
Maki KC, Kirkpatrick CF, Allison DB, Gadde KM. Maki KC, et al. Among authors: kirkpatrick cf. Expert Rev Endocrinol Metab. 2023 Sep-Nov;18(4):307-319. doi: 10.1080/17446651.2023.2209176. Epub 2023 May 18. Expert Rev Endocrinol Metab. 2023. PMID: 37199542 Review.
The use of medications to treat obesity is relatively rare. In part, this reflects concerns about long-term safety and weight loss effectiveness, possible provider bias, as well as lack of clear evidence of MACE risk reduction. ...
The use of medications to treat obesity is relatively rare. In part, this reflects concerns about long-term safety and weight loss ef …
Rescue Everolimus Post Lung Transplantation is Not Associated With an Increased Incidence of CLAD or CLAD-Related Mortality.
Ivulich S, Paraskeva M, Paul E, Kirkpatrick C, Dooley M, Snell G. Ivulich S, et al. Among authors: kirkpatrick c. Transpl Int. 2023 Feb 7;36:10581. doi: 10.3389/ti.2023.10581. eCollection 2023. Transpl Int. 2023. PMID: 36824294 Free PMC article.
Everolimus (EVE) has been used as a calcineurin inhibitor (CNI) minimization/ elimination agent or to augment immunosuppression in lung transplant recipients (LTR) with CNI-induced nephrotoxicity or neurotoxicity. The long-term evidence for survival and progression to chro …
Everolimus (EVE) has been used as a calcineurin inhibitor (CNI) minimization/ elimination agent or to augment immunosuppression in lung tran …
Enhanced primary care after hospitalization: General practitioner, pharmacist and patient feedback from the REMAIN HOME trial.
Foot H, Kirkpatrick C, Russell G, Sturman N, Cossart A, Freeman C. Foot H, et al. Among authors: kirkpatrick c. Res Social Adm Pharm. 2023 Mar;19(3):510-516. doi: 10.1016/j.sapharm.2022.09.014. Epub 2022 Oct 1. Res Social Adm Pharm. 2023. PMID: 36261303
The REMAIN HOME study investigated whether a pharmacist integrated into 14 different primary care teams in general practice (the "practice pharmacist model") reduces readmission to hospital for patients prescribed five or more long term medicines or high risk comorbidities …
The REMAIN HOME study investigated whether a pharmacist integrated into 14 different primary care teams in general practice (the "practice p …
Keto is Trending: Implications for Body Weight and Lipid Management.
Kirkpatrick CF, Willard KE, Maki KC. Kirkpatrick CF, et al. Curr Cardiol Rep. 2022 Sep;24(9):1093-1100. doi: 10.1007/s11886-022-01731-3. Epub 2022 Jul 6. Curr Cardiol Rep. 2022. PMID: 35794438 Review.
RECENT FINDINGS: VLC/KDs contribute to greater weight loss in the short term (< 6 months) compared to higher carbohydrate diets, but there is typically no difference between the diets by 12 months. ...
RECENT FINDINGS: VLC/KDs contribute to greater weight loss in the short term (< 6 months) compared to higher carbohydrate diets, b …
Pediatric SARS-CoV-2 Seroprevalence in Arkansas Over the First Year of the COVID-19 Pandemic.
Boehme KW, Kennedy JL, Snowden J, Owens SM, Kouassi M, Mann RL, Paredes A, Putt C, James L, Jin J, Du R, Kirkpatrick C, Modi Z, Caid K, Young S, Zohoori N, Kothari A, Boyanton BL, Craig Forrest J. Boehme KW, et al. Among authors: kirkpatrick c. J Pediatric Infect Dis Soc. 2022 Jun 22;11(6):248-256. doi: 10.1093/jpids/piac010. J Pediatric Infect Dis Soc. 2022. PMID: 35294550 Free PMC article.
With the emergence of SARS-CoV-2 variants, recognition of long-term effects of COVID-19, and the lack of an authorized pediatric SARS-CoV-2 vaccine at the time, these results highlight the importance of including children in SARS-CoV-2 public health, clinical care, and res …
With the emergence of SARS-CoV-2 variants, recognition of long-term effects of COVID-19, and the lack of an authorized pediatric SARS …
Multinucleated Giant Cells Induced by a Silk Fibroin Construct Express Proinflammatory Agents: An Immunohistological Study.
Al-Maawi S, Wang X, Sader R, Götz W, Motta A, Migliaresi C, Kirkpatrick CJ, Ghanaati S. Al-Maawi S, et al. Among authors: kirkpatrick cj. Materials (Basel). 2021 Jul 19;14(14):4038. doi: 10.3390/ma14144038. Materials (Basel). 2021. PMID: 34300957 Free PMC article.
Multinucleated giant cells (MNGCs) are frequently observed in the implantation areas of different biomaterials. The main aim of the present study was to analyze the long-term polarization pattern of the pro- and anti-inflammatory phenotypes of macrophages and MNGCs for 180 …
Multinucleated giant cells (MNGCs) are frequently observed in the implantation areas of different biomaterials. The main aim of the present …
Reducing Medical Admissions and Presentations Into Hospital through Optimising Medicines (REMAIN HOME): a stepped wedge, cluster randomised controlled trial.
Freeman CR, Scott IA, Hemming K, Connelly LB, Kirkpatrick CM, Coombes I, Whitty J, Martin J, Cottrell N, Sturman N, Russell GM, Williams I, Nicholson C, Kirsa S, Foot H. Freeman CR, et al. Among authors: kirkpatrick cm. Med J Aust. 2021 Mar;214(5):212-217. doi: 10.5694/mja2.50942. Epub 2021 Feb 12. Med J Aust. 2021. PMID: 33580553 Clinical Trial.
PARTICIPANTS: Adults discharged from one of seven study hospitals during the seven days preceding recruitment (22 May 2017 - 14 March 2018) and prescribed five or more long term medicines, or having a primary discharge diagnosis of congestive heart failure or exacerbation …
PARTICIPANTS: Adults discharged from one of seven study hospitals during the seven days preceding recruitment (22 May 2017 - 14 March 2018) …
Co-culture Model for Cutaneous Wound Healing to Assess a Porous Fiber-Based Drug Delivery System.
Dohle E, Scherrieble A, Doser M, Al-Maawi S, Hoss M, Dauner M, Sader R, Kirkpatrick CJ, Ghanaati S. Dohle E, et al. Among authors: kirkpatrick cj. Tissue Eng Part C Methods. 2020 Sep;26(9):475-484. doi: 10.1089/ten.TEC.2020.0145. Tissue Eng Part C Methods. 2020. PMID: 32829670
Co-cultivation of HDMEC and HDF results in the formation of microvessel-like structures in long-term co-cultures. The proposed in vitro co-culture model can be easily modified by adding macrophages to simulate the process of inflammation, thus allowing in vitro investigati …
Co-cultivation of HDMEC and HDF results in the formation of microvessel-like structures in long-term co-cultures. The proposed in vit …
The Effects of Carbohydrate-Restricted Dietary Patterns and Physical Activity on Body Weight and Glycemic Control.
Kirkpatrick CF, Liday C, Maki KC. Kirkpatrick CF, et al. Curr Atheroscler Rep. 2020 May 28;22(6):20. doi: 10.1007/s11883-020-00838-8. Curr Atheroscler Rep. 2020. PMID: 32468247 Review.
RECENT FINDINGS: Evidence supports the view that CHO-restricted interventions may be more effective than high-CHO, low-fat (HCLF) interventions in the short term for weight loss and glycemic control, but both produced similar levels of weight loss and glycemic control by 1 …
RECENT FINDINGS: Evidence supports the view that CHO-restricted interventions may be more effective than high-CHO, low-fat (HCLF) interventi …
Review of current evidence and clinical recommendations on the effects of low-carbohydrate and very-low-carbohydrate (including ketogenic) diets for the management of body weight and other cardiometabolic risk factors: A scientific statement from the National Lipid Association Nutrition and Lifestyle Task Force.
Kirkpatrick CF, Bolick JP, Kris-Etherton PM, Sikand G, Aspry KE, Soffer DE, Willard KE, Maki KC. Kirkpatrick CF, et al. J Clin Lipidol. 2019 Sep-Oct;13(5):689-711.e1. doi: 10.1016/j.jacl.2019.08.003. Epub 2019 Sep 13. J Clin Lipidol. 2019. PMID: 31611148 Free article. Review.
There was no clear evidence for advantages regarding effects on other cardiometabolic risk markers. Minimal data are available regarding long-term (>2 years) efficacy and safety. Clinicians are encouraged to consider the evidence discussed in this scientific statement w …
There was no clear evidence for advantages regarding effects on other cardiometabolic risk markers. Minimal data are available regarding lon …
69 results