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Year Number of Results
2006 1
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22 results

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Page 1
Low dose dexamethasone as treatment for women with heavy menstrual bleeding: A response-adaptive randomised placebo-controlled dose-finding parallel group trial (DexFEM).
Warner P, Whitaker LHR, Parker RA, Weir CJ, Douglas A, Hansen CH, Madhra M, Hillier SG, Saunders PTK, Iredale JP, Semple S, Slayden OD, Walker BR, Critchley HOD. Warner P, et al. EBioMedicine. 2021 Jul;69:103434. doi: 10.1016/j.ebiom.2021.103434. Epub 2021 Jul 2. EBioMedicine. 2021. PMID: 34218053 Free PMC article. Clinical Trial.
We investigated our hypothesis that HMB reflects impaired endometrial vasoconstriction due to endometrial glucocorticoid deficiency. Does reversing this deficiency, by short-term luteal-phase treatment with exogenous glucocorticoid (dexamethasone), ameliorate HMB? ...
We investigated our hypothesis that HMB reflects impaired endometrial vasoconstriction due to endometrial glucocorticoid deficiency. Does re …
Perinatal exposure to a high-fat diet is associated with reduced hepatic sympathetic innervation in one-year old male Japanese macaques.
Grant WF, Nicol LE, Thorn SR, Grove KL, Friedman JE, Marks DL. Grant WF, et al. PLoS One. 2012;7(10):e48119. doi: 10.1371/journal.pone.0048119. Epub 2012 Oct 30. PLoS One. 2012. PMID: 23118937 Free PMC article.
Our group recently demonstrated that maternal high-fat diet (HFD) consumption is associated with non-alcoholic fatty liver disease, increased apoptosis, and changes in gluconeogenic gene expression and chromatin structure in fetal nonhuman primate (NHP) liver. However, little is …
Our group recently demonstrated that maternal high-fat diet (HFD) consumption is associated with non-alcoholic fatty liver disease, increase …
Maternal azithromycin therapy for Ureaplasma intraamniotic infection delays preterm delivery and reduces fetal lung injury in a primate model.
Grigsby PL, Novy MJ, Sadowsky DW, Morgan TK, Long M, Acosta E, Duffy LB, Waites KB. Grigsby PL, et al. Am J Obstet Gynecol. 2012 Dec;207(6):475.e1-475.e14. doi: 10.1016/j.ajog.2012.10.871. Epub 2012 Oct 23. Am J Obstet Gynecol. 2012. PMID: 23111115 Free PMC article.
OBJECTIVE: We assessed the efficacy of a maternal multidose azithromycin (AZI) regimen, with and without antiinflammatory agents to delay preterm birth and to mitigate fetal lung injury associated with Ureaplasma parvum intraamniotic infection. STUDY DESIGN: Long-term …
OBJECTIVE: We assessed the efficacy of a maternal multidose azithromycin (AZI) regimen, with and without antiinflammatory agents to delay pr …
Isoflurane-induced apoptosis of oligodendrocytes in the neonatal primate brain.
Brambrink AM, Back SA, Riddle A, Gong X, Moravec MD, Dissen GA, Creeley CE, Dikranian KT, Olney JW. Brambrink AM, et al. Ann Neurol. 2012 Oct;72(4):525-35. doi: 10.1002/ana.23652. Ann Neurol. 2012. PMID: 23109147 Free PMC article.
Deletion of OLs at a stage when they are just beginning to myelinate axons could potentially have adverse long-term neurobehavioral consequences that might be additive to the potential consequences of isoflurane-induced neuroapoptosis....
Deletion of OLs at a stage when they are just beginning to myelinate axons could potentially have adverse long-term neurobehavioral c …
Ketamine-induced neuroapoptosis in the fetal and neonatal rhesus macaque brain.
Brambrink AM, Evers AS, Avidan MS, Farber NB, Smith DJ, Martin LD, Dissen GA, Creeley CE, Olney JW. Brambrink AM, et al. Anesthesiology. 2012 Feb;116(2):372-84. doi: 10.1097/ALN.0b013e318242b2cd. Anesthesiology. 2012. PMID: 22222480 Free PMC article.
METHOD: Ketamine was administered by IV infusion for 5 h to postnatal day 6 rhesus neonates or to pregnant rhesus females at 120 days' gestation (full term = 165 days). Three hours later, fetuses were delivered by cesarean section, and the fetal and neonatal brains were st …
METHOD: Ketamine was administered by IV infusion for 5 h to postnatal day 6 rhesus neonates or to pregnant rhesus females at 120 days' gesta …
Improving immunity in the elderly: current and future lessons from nonhuman primate models.
Meyer C, Kerns A, Haberthur K, Messaoudi I. Meyer C, et al. Age (Dordr). 2012 Oct;34(5):1157-68. doi: 10.1007/s11357-011-9353-y. Epub 2011 Dec 20. Age (Dordr). 2012. PMID: 22180097 Free PMC article. Review.
Aging results in several structural and functional changes in the immune system, often described under the umbrella term "immune senescence". Age-related changes affect both the innate and adaptive arms of the immune system and are believed to result in increased susceptib …
Aging results in several structural and functional changes in the immune system, often described under the umbrella term "immune sene …
Perimenopausal regulation of steroidogenesis in the nonhuman primate.
Sorwell KG, Kohama SG, Urbanski HF. Sorwell KG, et al. Neurobiol Aging. 2012 Jul;33(7):1487.e1-13. doi: 10.1016/j.neurobiolaging.2011.05.004. Epub 2011 Jun 17. Neurobiol Aging. 2012. PMID: 21683476 Free PMC article.
Furthermore, real-time PCR reveals an age-related attenuation of hippocampal expression level of the genes CYP17A1, STS, and 3BHSD1/2. Additionally, short-term administration of estradiol is associated with decreased expression of CYP17A1, STS, SULT2B1, and AROMATASE, cons …
Furthermore, real-time PCR reveals an age-related attenuation of hippocampal expression level of the genes CYP17A1, STS, and 3BHSD1/2. Addit …
In vivo delivery of FTY720 prevents radiation-induced ovarian failure and infertility in adult female nonhuman primates.
Zelinski MB, Murphy MK, Lawson MS, Jurisicova A, Pau KY, Toscano NP, Jacob DS, Fanton JK, Casper RF, Dertinger SD, Tilly JL. Zelinski MB, et al. Fertil Steril. 2011 Mar 15;95(4):1440-5.e1-7. doi: 10.1016/j.fertnstert.2011.01.012. Fertil Steril. 2011. PMID: 21316047 Free PMC article.
OBJECTIVE: To determine whether sphingosine-1-phosphate (S1P), or the S1P mimetic FTY720 shields ovaries of adult female rhesus monkeys from damage caused by 15 Gy of targeted radiotherapy, allowing for the retention of long-term fertility, and to evaluate whether S1P prot …
OBJECTIVE: To determine whether sphingosine-1-phosphate (S1P), or the S1P mimetic FTY720 shields ovaries of adult female rhesus monkeys from …
22 results