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Melanoma clonal heterogeneity leads to secondary resistance after adoptive cell therapy with tumor-infiltrating lymphocytes.
König D, Sandholzer M, Uzun S, Zingg A, Ritschard R, Thut H, Glatz K, Kappos EA, Schaefer DJ, Kettelhack C, Passweg JR, Holbro A, Baur K, Medinger M, Buser A, Lardinois D, Jeker LT, Khanna N, Stenner F, Kasenda B, Homicsko K, Matter M, Rodrigues Mantuano N, Zippelius A, Läubli H. König D, et al. Cancer Immunol Res. 2024 Apr 17. doi: 10.1158/2326-6066.CIR-23-0757. Online ahead of print. Cancer Immunol Res. 2024. PMID: 38631025
Adoptive cell therapy (ACT) with tumor-infiltrating lymphocytes (TIL) is effective in melanoma patients, although long-term responses seem restricted to patients who have complete remissions. ...
Adoptive cell therapy (ACT) with tumor-infiltrating lymphocytes (TIL) is effective in melanoma patients, although long-term responses …
Influence of specific collagen peptides and 12-week concurrent training on recovery-related biomechanical characteristics following exercise-induced muscle damage-A randomized controlled trial.
Bischof K, Stafilidis S, Bundschuh L, Oesser S, Baca A, König D. Bischof K, et al. Among authors: konig d. Front Nutr. 2023 Nov 16;10:1266056. doi: 10.3389/fnut.2023.1266056. eCollection 2023. Front Nutr. 2023. PMID: 38035363 Free PMC article.
INTRODUCTION: It has been shown that short-term ingestion of collagen peptides improves markers related to muscular recovery following exercise-induced muscle damage. The objective of the present study was to investigate whether and to what extent a longer-term spec …
INTRODUCTION: It has been shown that short-term ingestion of collagen peptides improves markers related to muscular recovery followin …
Longer-Term Effects of the Glycaemic Index on Substrate Metabolism and Performance in Endurance Athletes.
Moitzi AM, König D. Moitzi AM, et al. Among authors: konig d. Nutrients. 2023 Jul 4;15(13):3028. doi: 10.3390/nu15133028. Nutrients. 2023. PMID: 37447354 Free PMC article. Review.
Therefore, the aim of the following review is to elucidate the possible influence of the glycaemic index on substrate utilization during exercise and to clarify whether the consumption of a long-term high-carbohydrate diet with different glycaemic indices may have an influ …
Therefore, the aim of the following review is to elucidate the possible influence of the glycaemic index on substrate utilization during exe …
Effects of a Web-Based Lifestyle Intervention on Weight Loss and Cardiometabolic Risk Factors in Adults With Overweight and Obesity: Randomized Controlled Clinical Trial.
Kohl J, Brame J, Centner C, Wurst R, Fuchs R, Sehlbrede M, Tinsel I, Maiwald P, Fichtner UA, Armbruster C, Farin-Glattacker E, Gollhofer A, König D. Kohl J, et al. Among authors: konig d. J Med Internet Res. 2023 Jun 27;25:e43426. doi: 10.2196/43426. J Med Internet Res. 2023. PMID: 37368484 Free PMC article. Clinical Trial.
Web-based health programs are becoming increasingly interactive and can provide individuals with effective long-term weight management support. OBJECTIVE: The purpose of this randomized controlled clinical trial was to evaluate the effectiveness of an interactive web-based …
Web-based health programs are becoming increasingly interactive and can provide individuals with effective long-term weight managemen …
Parallels between oncogene-driven cardiac hyperplasia and heart regeneration in zebrafish.
Pfefferli C, Bonvin M, Grepper D, Robatel S, König D, Lischer HEL, Bruggmann R, Jaźwińska A. Pfefferli C, et al. Among authors: konig d. Development. 2023 Jun 15;150(12):dev201412. doi: 10.1242/dev.201412. Epub 2023 Jun 14. Development. 2023. PMID: 37314174
Among the differentially expressed genes, many proteasome and cell-cycle regulators were upregulated only in oncogene-expressing hearts. Preconditioning of the heart with short-term oncogene expression accelerated cardiac regeneration after cryoinjury, revealing a benefici …
Among the differentially expressed genes, many proteasome and cell-cycle regulators were upregulated only in oncogene-expressing hearts. Pre …
Evaluation of an Interactive Web-Based Health Program for Weight Loss-A Randomized Controlled Trial.
Fichtner UA, Armbruster C, Bischoff M, Maiwald P, Sehlbrede M, Tinsel I, Brame J, Kohl J, König D, Fuchs R, Wurst R, Farin-Glattacker E. Fichtner UA, et al. Among authors: konig d. Int J Environ Res Public Health. 2022 Nov 17;19(22):15157. doi: 10.3390/ijerph192215157. Int J Environ Res Public Health. 2022. PMID: 36429876 Free PMC article. Clinical Trial.
Personalized web-based interventions are promising in inducing behavioral change leading to effective reductions in body weight at relatively low costs. However, the long-term effects have not been thoroughly investigated. This work evaluates the effectiveness of web-based …
Personalized web-based interventions are promising in inducing behavioral change leading to effective reductions in body weight at relativel …
A new surgical approach to treatment of bilateral syngnathia in a patient with popliteal pterygium-syndrome.
Speth US, König D, Burg S, Köhnke R. Speth US, et al. Among authors: konig d. J Stomatol Oral Maxillofac Surg. 2022 Nov;123(6):e991-e994. doi: 10.1016/j.jormas.2022.06.012. Epub 2022 Jun 18. J Stomatol Oral Maxillofac Surg. 2022. PMID: 35728776
This case describes the treatment of syngnathia with a popliteal-pterygium syndrome. Although short-term successful surgical treatment has been described in literature, long-term follow up is essential, as the mouth opening limitations can be repetitively reoccurrin …
This case describes the treatment of syngnathia with a popliteal-pterygium syndrome. Although short-term successful surgical treatmen …
Supplementation of Specific Collagen Peptides Following High-Load Resistance Exercise Upregulates Gene Expression in Pathways Involved in Skeletal Muscle Signal Transduction.
Centner C, Jerger S, Mallard A, Herrmann A, Varfolomeeva E, Gollhofer S, Oesser S, Sticht C, Gretz N, Aagaard P, Nielsen JL, Frandsen U, Suetta C, Gollhofer A, König D. Centner C, et al. Among authors: konig d. Front Physiol. 2022 Apr 5;13:838004. doi: 10.3389/fphys.2022.838004. eCollection 2022. Front Physiol. 2022. PMID: 35480041 Free PMC article.
Further investigations should examine potential relationships between upregulated gene expression and changes in myofibrillar protein synthesis as well as potential long-term effects on anabolic pathways on the protein level....
Further investigations should examine potential relationships between upregulated gene expression and changes in myofibrillar protein synthe …
Corrigendum to 'Long-term outcomes of operable stage III NSCLC in the pre-immunotherapy era: results from a pooled analysis of the SAKK 16/96, SAKK 16/00, SAKK 16/01, and SAKK 16/08 trials': [ESMO Open Volume 7, Issue 2, (2022), 100455].
König D, Schär S, Vuong D, Guckenberger M, Furrer K, Opitz I, Weder W, Rothschild SI, Ochsenbein A, Zippelius A, Addeo A, Mark M, Eboulet EI, Hayoz S, Thierstein S, Betticher DC, Ris HB, Stupp R, Curioni-Fontecedro A, Peters S, Pless M, Früh M. König D, et al. ESMO Open. 2022 Jun;7(3):100494. doi: 10.1016/j.esmoop.2022.100494. Epub 2022 Apr 22. ESMO Open. 2022. PMID: 35468561 Free PMC article. No abstract available.
Long-term outcomes of operable stage III NSCLC in the pre-immunotherapy era: results from a pooled analysis of the SAKK 16/96, SAKK 16/00, SAKK 16/01, and SAKK 16/08 trials.
König D, Schär S, Vuong D, Guckenberger M, Furrer K, Opitz I, Weder W, Rothschild SI, Ochsenbein A, Zippelius A, Addeo A, Mark M, Eboulet EI, Hayoz S, Thierstein S, Betticher DC, Ris HB, Stupp R, Curioni-Fontecedro A, Peters S, Pless M, Früh M. König D, et al. ESMO Open. 2022 Apr;7(2):100455. doi: 10.1016/j.esmoop.2022.100455. Epub 2022 Apr 7. ESMO Open. 2022. PMID: 35398718 Free PMC article.
For patients with pCR, the 5- and 10-year event-free survival and OS rates were 45.7% [95% confidence interval (CI) 32.8% to 57.7%] and 28.1% (95% CI 15.2% to 42.6%), and 58.2% (95% CI 45.2% to 69.2%) and 45.0% (95% CI 31.5% to 57.6%), respectively. CONCLUSION: We report favorabl …
For patients with pCR, the 5- and 10-year event-free survival and OS rates were 45.7% [95% confidence interval (CI) 32.8% to 57.7%] and 28.1 …
32 results