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Sustained Pericarditis Recurrence Risk Reduction With Long-Term Rilonacept.
Imazio M, Klein AL, Brucato A, Abbate A, Arad M, Cremer PC, Insalaco A, LeWinter MM, Lewis BS, Lin D, Luis SA, Nicholls SJ, Sutej P, Wasserstrum Y, Clair J, Agarwal I, Wang S, Paolini JF; RHAPSODY Investigators. Imazio M, et al. J Am Heart Assoc. 2024 Mar 19;13(6):e032516. doi: 10.1161/JAHA.123.032516. Epub 2024 Mar 12. J Am Heart Assoc. 2024. PMID: 38471825 Free PMC article. Clinical Trial.
BACKGROUND: Rilonacept, a once-weekly interleukin-1 alpha and beta cytokine trap, reduced pericarditis recurrence in the phase 3 study, RHAPSODY (Rilonacept Inhibition of Interleukin-1 Alpha and Beta for Recurrent Pericarditis: A Pivotal Symptomatology and Outcomes Study). The RH …
BACKGROUND: Rilonacept, a once-weekly interleukin-1 alpha and beta cytokine trap, reduced pericarditis recurrence in the phase 3 study, RHAP …
Pediatric Recurrent Pericarditis: Appropriateness of the Standard of Care and Response to IL-1 Blockade.
Caorsi R, Insalaco A, Bovis F, Martini G, Cattalini M, Chinali M, Rimini A, Longo C, Federici S, Celani C, Filocamo G, Consolini R, Maggio MC, Fadanelli G, Licciardi F, Romano M, Teruzzi BL, Taddio A, Miniaci A, La Torre F, De Fanti A, Cavalli G, Bigucci B, Gallizzi R, Chinello M, Imazio M, Brucato A, Cimaz R, De Benedetti F, Gattorno M. Caorsi R, et al. Among authors: imazio m. J Pediatr. 2023 May;256:18-26.e8. doi: 10.1016/j.jpeds.2022.11.034. Epub 2022 Dec 5. J Pediatr. 2023. PMID: 36470465 Free article.
OBJECTIVE: To analyze, in a cohort of pediatric patients with recurrent pericarditis undergoing anti-interleukin (IL)-1 treatment: the agent and dosing used as first-line treatment, the long-term efficacy of IL-1 blockers, the percentage of patients achieving a drug-free r …
OBJECTIVE: To analyze, in a cohort of pediatric patients with recurrent pericarditis undergoing anti-interleukin (IL)-1 treatment: the agent …
Transition to rilonacept monotherapy from oral therapies in patients with recurrent pericarditis.
Brucato A, Wheeler A, Luis SA, Abbate A, Cremer PC, Zou L, Insalaco A, Lewinter M, Lewis BS, Lin D, Nicholls S, Pancrazi M, Klein AL, Imazio M, Paolini JF. Brucato A, et al. Among authors: imazio m. Heart. 2023 Jan 27;109(4):297-304. doi: 10.1136/heartjnl-2022-321328. Heart. 2023. PMID: 36316102 Free PMC article. Clinical Trial.
OBJECTIVE: Polypharmacy management of recurrent pericarditis (RP) often involves long-term therapies, often with negative effects. Slow tapering of oral therapies is often required to avoid recurrence. ...Median time to rilonacept monotherapy was similar regardless of gluc …
OBJECTIVE: Polypharmacy management of recurrent pericarditis (RP) often involves long-term therapies, often with negative effects. Sl …
[2022 Update on myocarditis and pericarditis following COVID-19 vaccination. Expert Opinion of the Italian Society of Cardiology].
Sinagra G, Porcari A, Merlo M, Fabris E, Imazio M, Barillà F, Basso C, Ciccone MM, Curcio A, Mancone M, Mercuro G, Muscoli S, Nodari S, Pedrinelli R, Spaccarotella C, Filardi PP, Indolfi C. Sinagra G, et al. Among authors: imazio m. G Ital Cardiol (Rome). 2022 Jun;23(6):408-413. doi: 10.1714/3810.37934. G Ital Cardiol (Rome). 2022. PMID: 35674028 Italian.
Recent epidemiological studies evaluated the incidence and risk of vaccine-associated myocarditis and pericarditis among men and women, in different ranges of age and specific types of vaccines. Long-term population analyses demonstrated that the cardiovascular risk confer …
Recent epidemiological studies evaluated the incidence and risk of vaccine-associated myocarditis and pericarditis among men and women, in d …
Consensus Statement Regarding the Efficacy and Safety of Long-Term Low-Dose Colchicine in Gout and Cardiovascular Disease.
Robinson PC, Terkeltaub R, Pillinger MH, Shah B, Karalis V, Karatza E, Liew D, Imazio M, Cornel JH, Thompson PL, Nidorf M. Robinson PC, et al. Among authors: imazio m. Am J Med. 2022 Jan;135(1):32-38. doi: 10.1016/j.amjmed.2021.07.025. Epub 2021 Aug 18. Am J Med. 2022. PMID: 34416165 Free PMC article. Review.
Over the last decade, evidence has demonstrated that long-term, low-dose colchicine (0.5 mg daily) is effective for preventing gout flare and cardiovascular (CV) events in a wide range of patients. ...Further, data accrued over the last 50 years strongly suggest that the b …
Over the last decade, evidence has demonstrated that long-term, low-dose colchicine (0.5 mg daily) is effective for preventing gout f …
Colchicine and the heart.
Imazio M, Nidorf M. Imazio M, et al. Eur Heart J. 2021 Jul 21;42(28):2745-2760. doi: 10.1093/eurheartj/ehab221. Eur Heart J. 2021. PMID: 33961006 Free PMC article. Review.
Early gastrointestinal intolerance limits its use in 10% of patients; however, 90% of patients tolerate it well over the long term. Despite isolated case reports, clinically relevant drug interactions with moderate to strong CYP3A4 inhibitors/competitors or P-glycoprotein …
Early gastrointestinal intolerance limits its use in 10% of patients; however, 90% of patients tolerate it well over the long term. D …
Pericarditis in patients with COVID-19: a systematic review.
Diaz-Arocutipa C, Saucedo-Chinchay J, Imazio M. Diaz-Arocutipa C, et al. Among authors: imazio m. J Cardiovasc Med (Hagerstown). 2021 Sep 1;22(9):693-700. doi: 10.2459/JCM.0000000000001202. J Cardiovasc Med (Hagerstown). 2021. PMID: 33927144
However, NSAIDs and colchicine were used in half or less of the cases. Overall, the short-term prognosis was good across groups....
However, NSAIDs and colchicine were used in half or less of the cases. Overall, the short-term prognosis was good across groups....
Management of nonischemic-dilated cardiomyopathies in clinical practice: a position paper of the working group on myocardial and pericardial diseases of Italian Society of Cardiology.
Merlo M, Masè M, Cannatà A, Zaffalon D, Lardieri G, Limongelli G, Imazio M, Canepa M, Castelletti S, Bauce B, Biagini E, Livi U, Severini GM, Dal Ferro M, Marra MP, Basso C, Autore C, Sinagra G. Merlo M, et al. Among authors: imazio m. J Cardiovasc Med (Hagerstown). 2020 Dec;21(12):927-943. doi: 10.2459/JCM.0000000000001050. J Cardiovasc Med (Hagerstown). 2020. PMID: 32740436
This position paper will summarize each step in NIDCM management, highlighting the multiple interactions between peripheral and referral centers, from first-line diagnostic workup and therapy to advanced heart failure management and long-term follow-up....
This position paper will summarize each step in NIDCM management, highlighting the multiple interactions between peripheral and referral cen …
ANMCO POSITION PAPER: The role of cardiology in the management of the health needs in the post-Covid-19 era.
Murrone A, Colivicchi F, Roncon L, Caldarola P, Amodeo V, Urbinati S, Di Lenarda A, Valente S, Aspromonte N, Cipriani M, Domenicucci S, Francese GM, Imazio M, Scotto di Uccio F, Scherillo M, Di Pasquale G, Gulizia MM, Gabrielli D. Murrone A, et al. Among authors: imazio m. Eur Heart J Suppl. 2020 Aug;22(Suppl G):G217-G222. doi: 10.1093/eurheartj/suaa110. Epub 2020 Aug 27. Eur Heart J Suppl. 2020. PMID: 38626256 Free PMC article.
In regards to the cardiac outpatient activities we need to identify short term goals, i.e. reschedule the suspended outpatient activities, revise the waiting lists, review the 'timings' of the bookings. ...The GP's collaboration could represent an important resource, a str …
In regards to the cardiac outpatient activities we need to identify short term goals, i.e. reschedule the suspended outpatient activi …
Cardiac tamponade: an educational review.
Imazio M, De Ferrari GM. Imazio M, et al. Eur Heart J Acute Cardiovasc Care. 2020 Jul 6:2048872620939341. doi: 10.1177/2048872620939341. Online ahead of print. Eur Heart J Acute Cardiovasc Care. 2020. PMID: 32628038
Cardiac tamponade in patients with cancer and metastatic involvement of the pericardium has a bad short-term prognosis because it is a sign of advanced cancer, on the contrary, patients with cardiac tamponade and a final diagnosis of idiopathic pericarditis generally have …
Cardiac tamponade in patients with cancer and metastatic involvement of the pericardium has a bad short-term prognosis because it is …
37 results