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Ageing is reversed, and metabolism is reset to young levels in recovering dauer larvae of C. elegans.
Houthoofd K, Braeckman BP, Lenaerts I, Brys K, De Vreese A, Van Eygen S, Vanfleteren JR. Houthoofd K, et al. Exp Gerontol. 2002 Aug-Sep;37(8-9):1015-21. doi: 10.1016/s0531-5565(02)00063-3. Exp Gerontol. 2002. PMID: 12213552
We have investigated physiological changes associated with long-term diapause survival, and found that dauer larvae slowly develop senescence-like symptoms, including decrease of metabolic capacity, aconitase enzyme activity, and ATP stores, and increase of lipofuscin- and …
We have investigated physiological changes associated with long-term diapause survival, and found that dauer larvae slowly develop se …