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Unraveling the dynamics of hepatitis C virus adaptive mutations and their impact on antiviral responses in primary human hepatocytes.
Frericks N, Brown RJP, Reinecke BM, Herrmann M, Brüggemann Y, Todt D, Miskey C, Vondran FWR, Steinmann E, Pietschmann T, Sheldon J. Frericks N, et al. Among authors: herrmann m. J Virol. 2024 Mar 19;98(3):e0192123. doi: 10.1128/jvi.01921-23. Epub 2024 Feb 6. J Virol. 2024. PMID: 38319104 Free PMC article.
In contrast, infection of primary human hepatocytes with p100pop led to a mild attenuation of virion production which correlated with a greater induction of cell-intrinsic antiviral defense responses. In summary, long-term passage experiments in cells where selective press …
In contrast, infection of primary human hepatocytes with p100pop led to a mild attenuation of virion production which correlated with a grea …
Hepatitis C virus cell culture adaptive mutations enhance cell culture propagation by multiple mechanisms but boost antiviral responses in primary human hepatocytes.
Frericks N, Brown RJP, Reinecke BM, Herrmann M, Brüggemann Y, Todt D, Miskey C, Vondran FWR, Steinmann E, Pietschmann T, Sheldon J. Frericks N, et al. Among authors: herrmann m. bioRxiv [Preprint]. 2023 Nov 22:2023.11.22.568224. doi: 10.1101/2023.11.22.568224. bioRxiv. 2023. PMID: 38045248 Free PMC article. Preprint.
In contrast, infection of primary human hepatocytes with p100pop led to a mild attenuation of virion production which correlated with a greater induction of cell-intrinsic antiviral defense responses. In summary, long-term passage experiments in cells where selective press …
In contrast, infection of primary human hepatocytes with p100pop led to a mild attenuation of virion production which correlated with a grea …
Vitamin D Status in Bipolar Disorder.
Späth Z, Tmava-Berisha A, Fellendorf FT, Stross T, Maget A, Platzer M, Bengesser SA, Häussl A, Zwigl I, Birner A, Queissner R, Stix K, Wels L, Lenger M, Dalkner N, Zelzer S, Herrmann M, Reininghaus EZ. Späth Z, et al. Among authors: herrmann m. Nutrients. 2023 Nov 11;15(22):4752. doi: 10.3390/nu15224752. Nutrients. 2023. PMID: 38004146 Free PMC article.
Based on the small effect size and the predominantly euthymic sample, further exploration in individuals with manic symptoms would be needed to confirm this association. In addition, long-term clinical markers and an assessment in different phases of the disease may provid …
Based on the small effect size and the predominantly euthymic sample, further exploration in individuals with manic symptoms would be needed …
Mechanisms of action underlying virtual reality exposure treatment in spider phobia: Pivotal role of within-session fear reduction.
Roesmann K, Leehr EJ, Böhnlein J, Gathmann B, Herrmann MJ, Junghöfer M, Schwarzmeier H, Seeger FR, Siminski N, Straube T, Dannlowski U, Lueken U. Roesmann K, et al. Among authors: herrmann mj. J Anxiety Disord. 2023 Dec;100:102790. doi: 10.1016/j.janxdis.2023.102790. Epub 2023 Oct 14. J Anxiety Disord. 2023. PMID: 37879242 Clinical Trial.
To predict long-term remission status at 6-month-follow-up, dimensional short-term changes in the SPQ and BAT were additionally included. Higher within-session fear reductions predicted better treatment outcomes (long-term SPQ; short- and long-term BAT …
To predict long-term remission status at 6-month-follow-up, dimensional short-term changes in the SPQ and BAT were additionall …
The Influence of Vitamin D Status on Cognitive Ability in Patients with Bipolar Disorder and Healthy Controls.
Leser B, Dalkner N, Tmava-Berisha A, Fellendorf FT, Unterrainer HF, Stross T, Maget A, Platzer M, Bengesser SA, Häussl A, Zwigl I, Birner A, Queissner R, Stix K, Wels L, Schönthaler EMD, Lenger M, Schwerdtfeger AR, Zelzer S, Herrmann M, Reininghaus EZ. Leser B, et al. Among authors: herrmann m. Nutrients. 2023 Sep 22;15(19):4111. doi: 10.3390/nu15194111. Nutrients. 2023. PMID: 37836395 Free PMC article.
Considering the current study's cross-sectional design, future research should expand these results in a longitudinal setting and include additional aspects of mental health, such as manic or depressive symptoms, long-term illness course and psychopharmacological treatment …
Considering the current study's cross-sectional design, future research should expand these results in a longitudinal setting and include ad …
Differential contribution of nitrifying prokaryotes to groundwater nitrification.
Krüger M, Chaudhari N, Thamdrup B, Overholt WA, Bristow LA, Taubert M, Küsel K, Jehmlich N, von Bergen M, Herrmann M. Krüger M, et al. Among authors: herrmann m. ISME J. 2023 Oct;17(10):1601-1611. doi: 10.1038/s41396-023-01471-4. Epub 2023 Jul 8. ISME J. 2023. PMID: 37422599 Free PMC article.
Nitrification rates were positively correlated to CMX clade A associated phylotypes and AOB affiliated with Nitrosomonas ureae. Short-term incubations amended with the nitrification inhibitors allylthiourea and chlorate suggested that AOB contributed a large fraction to ov …
Nitrification rates were positively correlated to CMX clade A associated phylotypes and AOB affiliated with Nitrosomonas ureae. Short-ter …
Additive efficacy of a bispecific anti-TNF/IL-6 nanobody compound in translational models of rheumatoid arthritis.
Biesemann N, Margerie D, Asbrand C, Rehberg M, Savova V, Agueusop I, Klemmer D, Ding-Pfennigdorff D, Schwahn U, Dudek M, Heyninck K, De Tavernier E, Cornelis S, Kohlmann M, Nestle FO, Herrmann M. Biesemann N, et al. Among authors: herrmann m. Sci Transl Med. 2023 Feb;15(681):eabq4419. doi: 10.1126/scitranslmed.abq4419. Epub 2023 Feb 1. Sci Transl Med. 2023. PMID: 36724239
Combining anti-TNF and anti-IL-6 antibodies in collagen-induced arthritis (CIA) mouse models resulted in sustained long-term remission, improved histology, and effects on bone remodeling pathways. ...
Combining anti-TNF and anti-IL-6 antibodies in collagen-induced arthritis (CIA) mouse models resulted in sustained long-term remissio …
The impact of moderate endurance exercise on cardiac telomeres and cardiovascular remodeling in obese rats.
Semeraro MD, Beltrami AP, Kharrat F, Almer G, Sedej S, Renner W, Gruber HJ, Curcio F, Herrmann M. Semeraro MD, et al. Among authors: herrmann m. Front Cardiovasc Med. 2023 Jan 6;9:1080077. doi: 10.3389/fcvm.2022.1080077. eCollection 2022. Front Cardiovasc Med. 2023. PMID: 36684585 Free PMC article.
CONCLUSION: HFD-induced obesity showed no effects on myocardial telomeres and induced only mild morphologic alterations. Summarized, long-term moderate endurance exercise partially reverses HFD-induced effects but may even trigger cardiac remodeling in the context of obesi …
CONCLUSION: HFD-induced obesity showed no effects on myocardial telomeres and induced only mild morphologic alterations. Summarized, long- …
Computational pathology in 2030: a Delphi study forecasting the role of AI in pathology within the next decade.
Berbís MA, McClintock DS, Bychkov A, Van der Laak J, Pantanowitz L, Lennerz JK, Cheng JY, Delahunt B, Egevad L, Eloy C, Farris AB 3rd, Fraggetta F, García Del Moral R, Hartman DJ, Herrmann MD, Hollemans E, Iczkowski KA, Karsan A, Kriegsmann M, Salama ME, Sinard JH, Tuthill JM, Williams B, Casado-Sánchez C, Sánchez-Turrión V, Luna A, Aneiros-Fernández J, Shen J. Berbís MA, et al. Among authors: herrmann md. EBioMedicine. 2023 Feb;88:104427. doi: 10.1016/j.ebiom.2022.104427. Epub 2023 Jan 4. EBioMedicine. 2023. PMID: 36603288 Free PMC article.
INTERPRETATION: This systematic consensus study details the expected short-to-mid-term impact of AI on pathology practice. These findings provide timely and relevant information regarding future care delivery in pathology and raise key practical, ethical, and legal challen …
INTERPRETATION: This systematic consensus study details the expected short-to-mid-term impact of AI on pathology practice. These find …
Hypothalamic integrity is necessary for sustained weight loss after bariatric surgery: A prospective, cross-sectional study.
Dischinger U, Kötzner L, Kovatcheva-Datchary P, Kleinschmidt H, Haas C, Perez J, Presek C, Koschker AC, Miras AD, Hankir MK, Vogel J, Germer CT, Fassnacht M, Herrmann MJ, Seyfried F. Dischinger U, et al. Among authors: herrmann mj. Metabolism. 2023 Jan;138:155341. doi: 10.1016/j.metabol.2022.155341. Epub 2022 Oct 27. Metabolism. 2023. PMID: 36341838 Free article.
Peripheral changes after bariatric surgery are not sufficient to induce satiety and long-term weight loss in patients with hypothalamic damage....
Peripheral changes after bariatric surgery are not sufficient to induce satiety and long-term weight loss in patients with hypothalam …
113 results