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A Randomized Controlled Trial of Long-Term (R)-alpha-Lipoic Acid Supplementation Promotes Weight Loss in Overweight or Obese Adults without Altering Baseline Elevated Plasma Triglyceride Concentrations.
Bobe G, Michels AJ, Zhang WJ, Purnell JQ, Woffendin C, Pereira C, Vita JA, Thomas NO, Traber MG, Frei B, Hagen TM. Bobe G, et al. Among authors: hagen tm. J Nutr. 2020 Sep 1;150(9):2336-2345. doi: 10.1093/jn/nxaa203. J Nutr. 2020. PMID: 32692358 Free PMC article. Clinical Trial.
Less urinary F2-isoprostanes (-25%; P = 0.005), blood leukocytes (-10.1%; P = 0.01), blood thrombocytes (-5.1%; P = 0.03), and ICAM-1 (-7.4%; P = 0.04) at 24 wk were also observed in the R-LA group than in placebo. CONCLUSIONS: Long-term LA supplementation results in BMI l …
Less urinary F2-isoprostanes (-25%; P = 0.005), blood leukocytes (-10.1%; P = 0.01), blood thrombocytes (-5.1%; P = 0.03), and ICAM-1 (-7.4% …
OLAM: A wearable, non-contact sensor for continuous heart-rate and activity monitoring.
Albright RK, Goska BJ, Hagen TM, Chi MY, Cauwenberghs G, Chiang PY. Albright RK, et al. Among authors: hagen tm. Annu Int Conf IEEE Eng Med Biol Soc. 2011;2011:5625-8. doi: 10.1109/IEMBS.2011.6091361. Annu Int Conf IEEE Eng Med Biol Soc. 2011. PMID: 22255615
Intended to be used in clinical trials for weeks at a time with no physician intervention, the OLAM allows continuous non-invasive monitoring of patients, providing the opportunity for long-term observation into a patient's physical activity and subtle longitudinal changes …
Intended to be used in clinical trials for weeks at a time with no physician intervention, the OLAM allows continuous non-invasive monitorin …
Acetyl-L-carnitine and alpha-lipoic acid supplementation of aged beagle dogs improves learning in two landmark discrimination tests.
Milgram NW, Araujo JA, Hagen TM, Treadwell BV, Ames BN. Milgram NW, et al. Among authors: hagen tm. FASEB J. 2007 Nov;21(13):3756-62. doi: 10.1096/fj.07-8531com. Epub 2007 Jul 10. FASEB J. 2007. PMID: 17622567
The improved performance on the landmark task of dogs supplemented with LA + ALC provides evidence of the effectiveness of this supplement in improving discrimination and allocentric spatial learning. We suggest that long-term maintenance on LA and ALC may be effective in …
The improved performance on the landmark task of dogs supplemented with LA + ALC provides evidence of the effectiveness of this supplement i …